tBID

BH3 interacting domain death agonist ; Homo sapiens







114 Article(s)
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51 20392206 The ubiquitin ligase Itch mediates the antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the truncated C-terminal portion of Bid. 2010 Mar 2
52 20404718 HIV-1 viral protein r induces ERK and caspase-8-dependent apoptosis in renal tubular epithelial cells. 2010 May 15 2
53 20655869 BAX insertion, oligomerization, and outer membrane permeabilization in brain mitochondria: role of permeability transition and SH-redox regulation. 2010 Nov 1
54 20978129 Activation of caspase-9, but not caspase-2 or caspase-8, is essential for heat-induced apoptosis in Jurkat cells. 2010 Dec 24 1
55 21368876 Giant unilamellar vesicles (GUVs) as a new tool for analysis of caspase-8/Bid-FL complex binding to cardiolipin and its functional activity. 2010 Dec 2 1
56 21666767 Activation of Multiple Molecular Mechanisms for Increasing Apoptosis in Human Glioblastoma T98G Xenograft. 2010 Jun 26 1
57 18368485 Molecular mechanisms of the combination of retinoid and interferon-gamma for inducing differentiation and increasing apoptosis in human glioblastoma T98G and U87MG cells. 2009 Jan 2
58 19233849 Cleavage of Bid by executioner caspases mediates feed forward amplification of mitochondrial outer membrane permeabilization during genotoxic stress-induced apoptosis in Jurkat cells. 2009 Apr 24 4
59 19381674 Galectin-1 induced activation of the mitochondrial apoptotic pathway: evidence for a connection between death-receptor and mitochondrial pathways in human Jurkat T lymphocytes. 2009 Aug 1
60 19454696 Granulysin induces cathepsin B release from lysosomes of target tumor cells to attack mitochondria through processing of bid leading to Necroptosis. 2009 Jun 1 1
61 19695221 Bcl-2 inhibitor and apigenin worked synergistically in human malignant neuroblastoma cell lines and increased apoptosis with activation of extrinsic and intrinsic pathways. 2009 Oct 30 1
62 19758996 Caspase-9 activation by the apoptosome is not required for fas-mediated apoptosis in type II Jurkat cells. 2009 Nov 27 2
63 19796174 Interaction of the alpha-helical H6 peptide from the pro-apoptotic protein tBid with cardiolipin. 2009 Nov 1
64 19820711 Membrane promotes tBID interaction with BCL(XL). 2009 Nov 2
65 17765974 Granzyme H induces apoptosis of target tumor cells characterized by DNA fragmentation and Bid-dependent mitochondrial damage. 2008 Feb 1
66 18098270 Combination of all-trans retinoic acid and paclitaxel-induced differentiation and apoptosis in human glioblastoma U87MG xenografts in nude mice. 2008 Feb 1 1
67 18173728 Bid is required in NPe6-PDT-induced apoptosis. 2008 Jan-Feb 1
68 18191430 Bax-mediated mitochondrial outer membrane permeabilization (MOMP), distinct from the mitochondrial permeability transition, is a key mechanism in diclofenac-induced hepatocyte injury: Multiple protective roles of cyclosporin A. 2008 Mar 15 1
69 18246124 Targeting human 8-oxoguanine DNA glycosylase to mitochondria protects cells from 2-methoxyestradiol-induced-mitochondria-dependent apoptosis. 2008 Jun 12 1
70 18252800 Evaluating cytochrome c diffusion in the intermembrane spaces of mitochondria during cytochrome c release. 2008 Mar 1 1
71 18602901 N-(4-Hydroxyphenyl) retinamide induced both differentiation and apoptosis in human glioblastoma T98G and U87MG cells. 2008 Aug 28 1
72 18667818 Sanguinarine, a benzophenanthridine alkaloid, induces apoptosis in MDA-MB-231 human breast carcinoma cells through a reactive oxygen species-mediated mitochondrial pathway. 2008 1
73 16888643 Cardiolipin deficiency releases cytochrome c from the inner mitochondrial membrane and accelerates stimuli-elicited apoptosis. 2007 Mar 1
74 17154276 tBid mediated activation of the mitochondrial death pathway leads to genetic ablation of the lens in Xenopus laevis. 2007 Jan 1
75 17308307 Granzyme K directly processes bid to release cytochrome c and endonuclease G leading to mitochondria-dependent cell death. 2007 Apr 20 1
76 17375293 Monte Carlo simulations of tBid association with the mitochondrial outer membrane. 2007 Dec 1
77 17440103 Sanguinarine-dependent induction of apoptosis in primary effusion lymphoma cells. 2007 Apr 15 1
78 17520191 Real-time monitoring full length bid interacting with Bax during TNF-alpha-induced apoptosis. 2007 Sep 1
79 17762183 Spatio-temporal dynamic analysis of bid activation and apoptosis induced by alkaline condition in human lung adenocarcinoma cell. 2007 1
80 18166654 Apoptosis induction by Bid requires unconventional ubiquitination and degradation of its N-terminal fragment. 2007 Dec 31 2
81 16380381 Mcl-1 interacts with truncated Bid and inhibits its induction of cytochrome c release and its role in receptor-mediated apoptosis. 2006 Mar 3 2
82 16407197 Real time single cell analysis of Bid cleavage and Bid translocation during caspase-dependent and neuronal caspase-independent apoptosis. 2006 Mar 3 3
83 16681997 HCV E2 may induce apoptosis of Huh-7 cells via a mitochondrial-related caspase pathway. 2006 Jun 23 1
84 16708390 Adenovirus-mediated tBid overexpression results in therapeutic effects on p53-resistant hepatocellular carcinoma. 2006 Oct 15 1
85 16741989 Re-evaluation of the distinction between type I and type II cells: the necessary role of the mitochondria in both the extrinsic and intrinsic signaling pathways upon Fas receptor activation. 2006 Sep 1
86 16826547 NMR determination that an extended BH3 motif of pro-apoptotic BID is specifically bound to BCL-XL. 2006 Jul 4
87 16987815 A membrane-targeted BID BCL-2 homology 3 peptide is sufficient for high potency activation of BAX in vitro. 2006 Dec 1 4
88 16988947 Mechanism of apoptosis with the involvement of calpain and caspase cascades in human malignant neuroblastoma SH-SY5Y cells exposed to flavonoids. 2006 Dec 1 2
89 15500442 Pro-apoptotic Bid induces membrane perturbation by inserting selected lysolipids into the bilayer. 2005 Apr 1 1
90 15637055 Specific cleavage of Mcl-1 by caspase-3 in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in Jurkat leukemia T cells. 2005 Mar 18 1
91 15661737 Humanin binds and nullifies Bid activity by blocking its activation of Bax and Bak. 2005 Apr 22 1
92 15846373 tBid induces alterations of mitochondrial fatty acid oxidation flux by malonyl-CoA-independent inhibition of carnitine palmitoyltransferase-1. 2005 Jun 1
93 16167168 Mitochondrial carrier homolog 2: a clue to cracking the BCL-2 family riddle? 2005 Jun 1
94 14701745 Akt inhibits apoptosis downstream of BID cleavage via a glucose-dependent mechanism involving mitochondrial hexokinases. 2004 Jan 2
95 14761678 A ginseng saponin metabolite-induced apoptosis in HepG2 cells involves a mitochondria-mediated pathway and its downstream caspase-8 activation and Bid cleavage. 2004 Feb 1 1
96 15123718 Conformation of membrane-associated proapoptotic tBid. 2004 Jul 9 1
97 15148322 Translocation of full-length Bid to mitochondria during anoikis. 2004 Jul 30 1
98 15262979 Sequential caspase-2 and caspase-8 activation upstream of mitochondria during ceramideand etoposide-induced apoptosis. 2004 Sep 24 1
99 15314281 The cardiolipin-binding domain of Bid affects mitochondrial respiration and enhances cytochrome c release. 2004 Sep 1
100 12519725 BID-D59A is a potent inducer of apoptosis in primary embryonic fibroblasts. 2003 Mar 21 1