Hyaluronic Acid

hyaluronan synthase 1 ; Homo sapiens







45 Article(s)
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1 35106474 Glycocalyx mechanotransduction mechanisms are involved in renal cancer metastasis. 2022 Feb 1
2 32551924 Effect of Prostaglandin D2 on mRNA Expression of Three Isoforms of Hyaluronic Acid Synthase in Nasal Polyp Fibroblasts. 2021 Jan 1
3 31276783 Intracellular hyaluronan: Importance for cellular functions. 2020 May 2
4 29709595 Activated hyaluronan metabolism in the tumor matrix - Causes and consequences. 2019 May 1
5 30507579 Increased Hyaluronan and TSG-6 in Association with Neuropathologic Changes of Alzheimer's Disease. 2019 1
6 31075987 α-Ionone Protects Against UVB-Induced Photoaging in Human Dermal Fibroblasts. 2019 May 9 1
7 29063508 Age-related changes in cyclic phosphatidic acid-induced hyaluronic acid synthesis in human fibroblasts. 2018 Jan 1
8 28604766 The deubiquitinating enzymes USP4 and USP17 target hyaluronan synthase 2 and differentially affect its function. 2017 Jun 12 1
9 29137675 Human hyaluronic acid synthase-1 promotes malignant transformation via epithelial-to-mesenchymal transition, micronucleation and centrosome abnormalities. 2017 Nov 14 2
10 26627828 Hyaluronan Does Not Regulate Human Epidermal Keratinocyte Proliferation and Differentiation. 2016 Mar 18 2
11 26883802 UDP-sugar substrates of HAS3 regulate its O-GlcNAcylation, intracellular traffic, extracellular shedding and correlate with melanoma progression. 2016 Aug 1
12 24590928 The decreased secretion of hyaluronan by older human fibroblasts under physiological conditions is mainly associated with the down-regulated expression of hyaluronan synthases but not with the expression levels of hyaluronidases. 2015 Aug 1
13 25699059 Hyaluronan synthase 1: a mysterious enzyme with unexpected functions. 2015 3
14 25795779 Fluorescence resonance energy transfer (FRET) and proximity ligation assays reveal functionally relevant homo- and heteromeric complexes among hyaluronan synthases HAS1, HAS2, and HAS3. 2015 May 1 3
15 25843802 Identification and analysis of the promoter region of the human HAS3 gene. 2015 May 15 2
16 26448759 Correlative Light and Electron Microscopy Reveals the HAS3-Induced Dorsal Plasma Membrane Ruffles. 2015 1
17 24099991 Hyaluronan synthase 1 (HAS1) produces a cytokine-and glucose-inducible, CD44-dependent cell surface coat. 2014 Jan 1 3
18 24406795 Extensive CD44-dependent hyaluronan coats on human bone marrow-derived mesenchymal stem cells produced by hyaluronan synthases HAS1, HAS2 and HAS3. 2014 Mar 1
19 24509846 Rab10-mediated endocytosis of the hyaluronan synthase HAS3 regulates hyaluronan synthesis and cell adhesion to collagen. 2014 Mar 21 1
20 24658508 Hyaluronan metabolism in human keratinocytes and atopic dermatitis skin is driven by a balance of hyaluronan synthases 1 and 3. 2014 Aug 3
21 24668563 Elevated hyaluronan and hyaluronan-mediated motility receptor are associated with biochemical failure in patients with intermediate-grade prostate tumors. 2014 Jun 15 1
22 23303191 Hyaluronan synthase 1 (HAS1) requires higher cellular UDP-GlcNAc concentration than HAS2 and HAS3. 2013 Feb 22 2
23 21887686 Molecular characterization of kidney cancer: association of hyaluronic acid family with histological subtypes and metastasis. 2012 May 1 1
24 22184056 Hyaluronan is required for cranial neural crest cells migration and craniofacial development. 2012 Feb 2
25 22270036 Pycnogenol® effects on skin elasticity and hydration coincide with increased gene expressions of collagen type I and hyaluronic acid synthase in women. 2012 1
26 20960509 Association of hyaluronic acid family members (HAS1, HAS2, and HYAL-1) with bladder cancer diagnosis and prognosis. 2011 Mar 15 1
27 21576248 Divergent Sp1 protein levels may underlie differential expression of UDP-glucose dehydrogenase by fibroblasts: role in susceptibility to orbital Graves disease. 2011 Jul 8 1
28 21743962 Fragmented hyaluronan is an autocrine chemokinetic motility factor supported by the HAS2-HYAL2/CD44 system on the plasma membrane. 2011 Nov 2
29 20384487 Effects of thyrotropin and thyrotropin-receptor-stimulating Graves' disease immunoglobulin G on cyclic adenosine monophosphate and hyaluronan production in nondifferentiated orbital fibroblasts of Graves' ophthalmopathy patients. 2010 May 2
30 20501660 Methyl-beta-cyclodextrin suppresses hyaluronan synthesis by down-regulation of hyaluronan synthase 2 through inhibition of Akt. 2010 Jul 23 1
31 20875124 Hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in the accumulation of hyaluronan in endometrioid endometrial carcinoma. 2010 Sep 27 1
32 19435493 Expression of hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in serous ovarian carcinomas: inverse correlation between HYAL1 and hyaluronan content. 2009 May 12 1
33 21977277 HAS-1 genetic polymorphism in sporadic abdominal aortic aneurysm. 2009 Jun 30 1
34 18400745 Hyaluronan production in synoviocytes as a consequence of viral infections: HAS1 activation by Epstein-Barr virus and synthetic double- and single-stranded viral RNA analogs. 2008 Jun 13 1
35 18768572 Increased hyaluronic acid content in idiopathic pulmonary arterial hypertension. 2008 Dec 3
36 16522194 Recombinant human hyaluronan synthase 3 is phosphorylated in mammalian cells. 2006 Jun 1 1
37 16603733 Sp1 and Sp3 mediate constitutive transcription of the human hyaluronan synthase 2 gene. 2006 Jun 30 1
38 15731173 Intronic splicing of hyaluronan synthase 1 (HAS1): a biologically relevant indicator of poor outcome in multiple myeloma. 2005 Jun 15 1
39 15794859 Potential impact of a single nucleotide polymorphism in the hyaluronan synthase 1 gene in Waldenstrom's macroglobulinemia. 2005 Mar 1
40 15870928 Role of hyaluronan and hyaluronan synthase in endometrial cancer. 2005 Jun 1
41 14988410 Identification and analysis of the promoter region of the human hyaluronan synthase 2 gene. 2004 May 14 2
42 15231668 Hyaluronan facilitates invasion of colon carcinoma cells in vitro via interaction with CD44. 2004 Jul 1 2
43 12757764 The human hyaluronan synthase genes: genomic structures, proximal promoters and polymorphic microsatellite markers. 2003 Aug 1
44 11453924 Reticular erythematous mucinosis syndrome with an infiltration of factor XIIIa+ and hyaluronan synthase 2+ dermal dendrocytes. 2001 Jul 4
45 10455188 Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties. 1999 Aug 27 3