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fatty acid amide hydrolase ; Homo sapiens







34 Article(s)
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1 34756920 Concentration-dependent effects of chlorpyrifos oxon on peroxisome proliferator-activated receptor signaling in MCF-7 cells. 2022 Feb 1
2 34983657 Assessment of NSAIDs as potential inhibitors of the fatty acid amide hydrolase I (FAAH-1) using three different primary fatty acid amide substrates in vitro. 2022 Jan 4 1
3 34995983 1-, 2- and 3-AG as substrates of the endocannabinoid enzymes and endogenous ligands of the cannabinoid receptor 1. 2022 Feb 5 1
4 33070154 The effects of inhibition of fatty acid amide hydrolase (FAAH) by JNJ-42165279 in social anxiety disorder: a double-blind, randomized, placebo-controlled proof-of-concept study. 2021 Apr 2
5 33607363 Design and synthesis of new carbamates as inhibitors for fatty acid amide hydrolase and cholinesterases: Molecular dynamic, in vitro and in vivo studies. 2021 Apr 4
6 33723207 Fear extinction learning and anandamide: an fMRI study in healthy humans. 2021 Mar 15 3
7 33834617 Anticancer Potential of Small-Molecule Inhibitors of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase. 2021 Jul 20 2
8 34217798 The role of endocannabinoid pathway in the neuropathology of Alzheimer's disease: Can the inhibitors of MAGL and FAAH prove to be potential therapeutic targets against the cognitive impairment associated with Alzheimer's disease? 2021 Sep 2
9 34893921 FAAH polymorphism (rs324420) modulates extinction recall in healthy humans: an fMRI study. 2021 Dec 10 3
10 32041998 The endocannabinoid hydrolase FAAH is an allosteric enzyme. 2020 Feb 10 3
11 32292082 Advances in the discovery of fatty acid amide hydrolase inhibitors: what does the future hold? 2020 Jul 4
12 32681461 The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASP3652 in First-in-Human and Ascending Multiple Oral Dose Studies in Healthy Subjects. 2020 Sep 1
13 33374180 In Silico and In Vitro Analysis of Major Cannabis-Derived Compounds as Fatty Acid Amide Hydrolase Inhibitors. 2020 Dec 24 2
14 30532004 Impaired anandamide/palmitoylethanolamide signaling in hippocampal glutamatergic neurons alters synaptic plasticity, learning, and emotional responses. 2019 Jul 2
15 30739035 Brain permeant and impermeant inhibitors of fatty-acid amide hydrolase suppress the development and maintenance of paclitaxel-induced neuropathic pain without producing tolerance or physical dependence in vivo and synergize with paclitaxel to reduce tumor cell line viability in vitro. 2019 Apr 2
16 30822695 Posttreatment With the Fatty Acid Amide Hydrolase Inhibitor URB937 Ameliorates One-Lung Ventilation-Induced Lung Injury in a Rabbit Model. 2019 Jul 1
17 30842391 New Insights of Uterine Leiomyoma Pathogenesis: Endocannabinoid System. 2019 Mar 7 2
18 31117309 Three-Dimensional Quantitative Structure-Activity Relationships (3D-QSAR) on a Series of Piperazine-Carboxamides Fatty Acid Amide Hydrolase (FAAH) Inhibitors as a Useful Tool for the Design of New Cannabinoid Ligands. 2019 May 21 1
19 30114402 Neuroprotective effects of fatty acid amide hydrolase catabolic enzyme inhibition in a HIV-1 Tat model of neuroAIDS. 2018 Oct 1
20 30126012 FAAH variant Pro129Thr modulates subjective effects produced by cocaine administration. 2018 Oct 1
21 27000802 Metabolism of Anandamide by Human Cytochrome P450 2J2 in the Reconstituted System and Human Intestinal Microsomes. 2016 Jun 2
22 27516570 Metabolism of endocannabinoids. 2016 Aug 11 1
23 27790143 A Personal Retrospective: Elevating Anandamide (AEA) by Targeting Fatty Acid Amide Hydrolase (FAAH) and the Fatty Acid Binding Proteins (FABPs). 2016 1
24 25519724 A simple method for simultaneous determination of N-arachidonoylethanolamine, N-oleoylethanolamine, N-palmitoylethanolamine and 2-arachidonoylglycerol in human cells. 2015 Feb 1
25 25975960 Endocannabinoid and ceramide levels are altered in patients with colorectal cancer. 2015 Jul 1
26 23347118 Inhibition of fatty acid amide hydrolase activates Nrf2 signalling and induces heme oxygenase 1 transcription in breast cancer cells. 2013 Oct 4
27 23488865 Latest advances in the discovery of fatty acid amide hydrolase inhibitors. 2013 May 2
28 21924613 Discovery of novel spirocyclic inhibitors of fatty acid amide hydrolase (FAAH). Part 2. Discovery of 7-azaspiro[3.5]nonane urea PF-04862853, an orally efficacious inhibitor of fatty acid amide hydrolase (FAAH) for pain. 2011 Nov 1 2
29 20096328 Methylation and acetylation of 15-hydroxyanandamide modulate its interaction with the endocannabinoid system. 2010 Apr 2
30 17553686 Severe deficiency of the fatty acid amide hydrolase (FAAH) activity segregates with the Huntington's disease mutation in peripheral lymphocytes. 2007 Jul 2
31 17901541 Studies of anandamide accumulation inhibitors in cerebellar granule neurons: comparison to inhibition of fatty acid amide hydrolase. 2007 Sep 3
32 16375688 Partial QSAR analysis of some selected natural inhibitors of FAAH suggests a working hypothesis for the development of endocannabinoid-based drugs. 2005 Dec 2
33 11585048 Fatty acid amide hydrolase: biochemistry, pharmacology, and therapeutic possibilities for an enzyme hydrolyzing anandamide, 2-arachidonoylglycerol, palmitoylethanolamide, and oleamide. 2001 Sep 1 1
34 10820223 Structure-activity relationships among N-arachidonylethanolamine (Anandamide) head group analogues for the anandamide transporter. 2000 Jun 1