alectinib

anaplastic lymphoma kinase ; Mus musculus







13 Article(s)
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1 34520436 Sensitivity of eight types of ALK fusion variant to alectinib in ALK-transformed cells. 2022 Feb 1 6
2 33728771 The ALK inhibitors, alectinib and ceritinib, induce ALK-independent and STAT3-dependent glioblastoma cell death. 2021 Jun 1
3 33758275 Efficacy of combination treatment using YHO-1701, an orally active STAT3 inhibitor, with molecular-targeted agents on cancer cell lines. 2021 Mar 23 1
4 34176264 Development of Alectinib-Based PROTACs as Novel Potent Degraders of Anaplastic Lymphoma Kinase (ALK). 2021 Jul 8 6
5 31972351 Osimertinib Overcomes Alectinib Resistance Caused by Amphiregulin in a Leptomeningeal Carcinomatosis Model of ALK-Rearranged Lung Cancer. 2020 May 1
6 31334113 Alectinib, an Anaplastic Lymphoma Kinase Inhibitor, Abolishes ALK Activity and Growth in ALK-Positive Neuroblastoma Cells. 2019 1
7 30149189 Bioanalytical liquid chromatography-tandem mass spectrometric assay for the quantification of the ALK inhibitors alectinib, brigatinib and lorlatinib in plasma and mouse tissue homogenates. 2018 Nov 30 1
8 28455243 The second-generation ALK inhibitor alectinib effectively induces apoptosis in human neuroblastoma cells and inhibits tumor growth in a TH-MYCN transgenic neuroblastoma mouse model. 2017 Aug 1 4
9 29048652 Activation of Src signaling mediates acquired resistance to ALK inhibition in lung cancer. 2017 Nov 3
10 26682573 Activation of EGFR Bypass Signaling by TGFα Overexpression Induces Acquired Resistance to Alectinib in ALK-Translocated Lung Cancer Cells. 2016 Jan 1
11 26849637 Antitumor activity of alectinib, a selective ALK inhibitor, in an ALK-positive NSCLC cell line harboring G1269A mutation: Efficacy of alectinib against ALK G1269A mutated cells. 2016 Mar 1
12 25556163 Rapid response of brain metastases to alectinib in a patient with non-small-cell lung cancer resistant to crizotinib. 2015 Feb 1
13 26019170 Induction of PD-L1 Expression by the EML4-ALK Oncoprotein and Downstream Signaling Pathways in Non-Small Cell Lung Cancer. 2015 Sep 1 1