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dihydropyrimidine dehydrogenase ; Homo sapiens







8 Article(s)
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1 34780066 DPYD polymorphisms c.496A>G, c.2194G>A and c.85T>C and risk of severe adverse drug reactions in patients treated with fluoropyrimidine-based protocols. 2022 May 2
2 35239419 Survey of US Medical Oncologists' Practices and Beliefs Regarding DPYD Testing Before Fluoropyrimidine Chemotherapy. 2022 Jun 1
3 32423482 DPD status and fluoropyrimidines-based treatment: high activity matters too. 2020 May 18 2
4 32619063 Impact of DPYD, DPYS, and UPB1 gene variations on severe drug-related toxicity in patients with cancer. 2020 Sep 1
5 32899374 A Genotyping/Phenotyping Approach with Careful Clinical Monitoring to Manage the Fluoropyrimidines-Based Therapy: Clinical Cases and Systematic Review of the Literature. 2020 Sep 3 3
6 30361102 Standard fluoropyrimidine dosages in chemoradiation therapy result in an increased risk of severe toxicity in DPYD variant allele carriers. 2018 Nov 2
7 21344302 Final results of a prematurely discontinued Phase 1/2 study of eniluracil with escalating doses of 5-fluorouracil administered orally in patients with advanced hepatocellular carcinoma. 2011 Oct 1
8 19288105 Lack of large intragenic rearrangements in dihydropyrimidine dehydrogenase (DPYD) gene in fluoropyrimidine-treated patients with high-grade toxicity. 2009 Aug 1