| 1 |
30944635 | 5-Fluorouracil-based adjuvant chemotherapy improves the clinical outcomes of patients with lymphovascular invasion of upper urinary tract cancer and low expression of dihydropyrimidine dehydrogenase. | 2019 May |
2 |
| 2 |
28835573 | Higher Tissue Levels of Thymidylate Synthase Determined by ELISA Are Associated with Poor Prognosis of Patients with Lung Cancer. | 2017 Aug |
1 |
| 3 |
26651493 | Uncommon dihydropyrimidine dehydrogenase mutations and toxicity by fluoropyrimidines: a lethal case with a new variant. | 2016 |
1 |
| 4 |
23585145 | Fluoropyrimidine toxicity in patients with dihydropyrimidine dehydrogenase splice site variant: the need for further revision of dose and schedule. | 2013 Aug |
2 |
| 5 |
28520376 | Fluorouracil Therapy and DPYD Genotype | 2012 |
1 |
| 6 |
21378348 | A phase I study evaluating the effect of CDHP as a component of S-1 on the pharmacokinetics of 5-fluorouracil. | 2011 Feb |
1 |
| 7 |
20146975 | [Dihydropyrimidine dehydrogenase deficiency and toxicity to fluoropyrimidine]. | 2010 Jan-Feb |
4 |
| 8 |
19015148 | Comparison of 5-fluorouracil-related gene expression levels between adenocarcinomas and squamous cell carcinomas of the lung. | 2009 Jan |
2 |
| 9 |
17143493 | Cyclophosphamide augments the anti-tumor efficacy of uracil and tegafur by inhibiting dihydropyrimidine dehydrogenase. | 2007 Jan |
2 |
| 10 |
17603216 | Development of a pharmacokinetic model to optimize the dosage regimen of TS-1, a combination preparation of tegafur, gimeracil and oteracil potassium. | 2007 Jun |
4 |
| 11 |
17695427 | Predictive value of thymidylate synthase and dihydropyrimidine dehydrogenase expression in tumor tissue, regarding the efficacy of postoperatively administered UFT (tegafur+uracil) in patients with non-small cell lung cancer. | 2007 Jul-Aug |
1 |
| 12 |
17952005 | Dihydropyrimidine dehydrogenase activity during long-term adjuvant treatment with oral uracil and tegafur for colorectal cancer. | 2007 |
1 |
| 13 |
16897969 | [Pharmacokinetics of S-1]. | 2006 Jun |
4 |
| 14 |
16897985 | Rapid development of S-1 in the west for therapy of advanced gastric carcinoma. | 2006 Jun |
2 |
| 15 |
15598584 | Dihydropyrimidine dehydrogenase expression predicts survival outcome and chemosensitivity to 5-fluorouracil in patients with oral squamous cell carcinoma. | 2005 Jan |
2 |
| 16 |
15363468 | The role of uracil-tegafur (UFT) in elderly patients with colorectal cancer. | 2004 Oct |
2 |
| 17 |
12775012 | S-1 in gastric cancer: a comprehensive review. | 2003 |
1 |
| 18 |
12851836 | Clinical implications of dihydropyrimidine dehydrogenase (DPD) activity in 5-FU-based chemotherapy: mutations in the DPD gene, and DPD inhibitory fluoropyrimidines. | 2003 Jun |
2 |
| 19 |
14551502 | Dihydropyrimidine dehydrogenase inhibition as a strategy for the oral administration of 5-fluorouracil: utility in the treatment of advanced colorectal cancer. | 2003 Oct |
1 |
| 20 |
12111108 | Pharmacokinetic study of S-1, a novel oral fluorouracil antitumor agent in animal model and in patients with impaired renal function. | 2002 Jul |
2 |
| 21 |
12355409 | Predictive value of dihydropyrimidine dehydrogenase expression in tumor tissue, regarding the efficacy of postoperatively administered UFT (Tegafur + Uracil) in patients with p-stage I nonsmall-cell lung cancer. | 2002 Oct |
2 |
| 22 |
12464897 | Thymidylate synthase and dihydropyrimidine dehydrogenase expression in oral squamous cell carcinoma: an immunohistochemical and clinicopathologic study. | 2002 Dec |
1 |
| 23 |
11219978 | UFT in the treatment of colorectal and breast cancer. | 2001 Jan |
2 |
| 24 |
11679189 | The role of UFT and the combination of UFT/leucovorin in non-small cell lung cancer. | 2001 Nov |
1 |
| 25 |
11729480 | [Dihydropyrimidine dehydrogenase activity in urothelial cancer--influence of UFT administration on DPD activity]. | 2001 Nov |
1 |
| 26 |
10473078 | Pharmacokinetic study of S-1, a novel oral fluorouracil antitumor drug. | 1999 Aug |
4 |
| 27 |
10595802 | Novel oral fluoropyrimidines in the treatment of metastatic colorectal cancer. | 1999 Dec 1 |
2 |