Uracil

dihydropyrimidine dehydrogenase ; Homo sapiens







84 Article(s)
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51 16151913 Dihydropyrimidine dehydrogenase deficiency presenting at birth. 2005 1
52 14705962 New insights in dihydropyrimidine dehydrogenase deficiency: a pivotal role for beta-aminoisobutyric acid? 2004 Apr 1 1
53 14744810 Circadian rhythm of dihydrouracil/uracil ratios in biological fluids: a potential biomarker for dihydropyrimidine dehydrogenase levels. 2004 Feb 7
54 15271097 A simple and rapid high-performance liquid chromatographic (HPLC) method for 5-fluorouracil (5-FU) assay in plasma and possible detection of patients with impaired dihydropyrimidine dehydrogenase (DPD) activity. 2004 Aug 1
55 12557710 [Combined determination of urine uracil levels and plasma 5-FU clearance for a simple order-made treatment with anticancer agents of FU derivative]. 2003 Jan 1
56 12739060 Pharmacokinetics of S-1, an oral formulation of ftorafur, oxonic acid and 5-chloro-2,4-dihydroxypyridine (molar ratio 1:0.4:1) in patients with solid tumors. 2003 Jul 1
57 12751387 Significance of dihydropyrimidine dehydrogenase activity in renal cell carcinoma. 2003 Mar 2
58 14551502 Dihydropyrimidine dehydrogenase inhibition as a strategy for the oral administration of 5-fluorouracil: utility in the treatment of advanced colorectal cancer. 2003 Oct 1
59 14712769 [Support of TS-1, 5-FU preparation containing potent DPD inhibitor by determination of urinary uracil/serum 5-FU clearance]. 2003 Dec 3
60 11896120 Comparative pharmacokinetic study of continuous venous infusion fluorouracil and oral fluorouracil with eniluracil in patients with advanced solid tumors. 2002 Mar 15 2
61 11984087 Dihydropyrimidine dehydrogenase-related enzymes predict efficacy and adverse reactions of UFT1+cisplatin neoadjuvant chemotherapy for gastric cancer. 2002 Apr 1
62 12006517 Impact of two weekly schedules of oral eniluracil given with fluorouracil and leucovorin on the duration of dihydropyrimidine dehydrogenase inhibition. 2002 May 2
63 12074825 Porous graphitic carbon shows promise for the rapid screening partial DPD deficiency in lymphocyte dihydropyrimidine dehydrogenase in Chinese, Indian and Malay in Singapore by using semi-automated HPLC-radioassay. 2002 May 1
64 12076692 Simple liquid chromatographic method for the determination of uracil and dihydrouracil plasma levels: a potential pretreatment predictor of 5-fluorouracil toxicity. 2002 Jul 15 2
65 12355409 Predictive value of dihydropyrimidine dehydrogenase expression in tumor tissue, regarding the efficacy of postoperatively administered UFT (Tegafur + Uracil) in patients with p-stage I nonsmall-cell lung cancer. 2002 Oct 1
66 11241325 UFT plus oral leucovorin calcium (Orzel) and radiation in combined modality therapy: a comprehensive review. 2001 Feb 20 1
67 11290431 The significance of dihydropyrimidine dehydrogenase (DPD) activity in bladder cancer. 2001 Mar 2
68 11668512 Thymidine phosphorylase and dihydropyrimidine dehydrogenase protein expression in colorectal cancer. 2001 Oct 15 2
69 10620566 Pitfalls in the diagnosis of patients with a partial dihydropyrimidine dehydrogenase deficiency. 2000 Jan 2
70 11060767 Eniluracil: an irreversible inhibitor of dihydropyrimidine dehydrogenase. 2000 Jul 1
71 10071185 Genotype and phenotype in patients with dihydropyrimidine dehydrogenase deficiency. 1999 Jan 1
72 10499634 Regulation of dihydropyrimidine dehydrogenase in colorectal cancer. 1999 Sep 2
73 10595802 Novel oral fluoropyrimidines in the treatment of metastatic colorectal cancer. 1999 Dec 1 1
74 9636062 Secondary tritium and solvent deuterium isotope effects as a probe of the reaction catalyzed by porcine recombinant dihydropyrimidine dehydrogenase. 1998 Jun 23 1
75 9679586 [A case of gastric cancer with decreased dihydropyrimidine dehydrogenase activity]. 1998 Jul 1
76 9704742 Uracil-tegafur in gastric carcinoma: a comprehensive review. 1998 Aug 2
77 9164418 The effect of sorivudine on dihydropyrimidine dehydrogenase activity in patients with acute herpes zoster. 1997 May 1
78 9254861 Identification of a four-base deletion (delTCAT296-299) in the dihydropyrimidine dehydrogenase gene with variable clinical expression. 1997 Aug 1
79 9323539 Semi-automated radioassay for determination of dihydropyrimidine dehydrogenase (DPD) activity. Screening cancer patients for DPD deficiency, a condition associated with 5-fluorouracil toxicity. 1997 Aug 29 2
80 21528302 Enhancing 5-fluorouracil cytotoxicity by inhibiting dihydropyrimidine dehydrogenase activity with uracil in human tumor cells. 1997 Nov 7
81 7929074 Dehalogenating and NADPH-modifying activities of dihydropyrimidine dehydrogenase. 1994 Sep 30 3
82 8083224 cDNA cloning and chromosome mapping of human dihydropyrimidine dehydrogenase, an enzyme associated with 5-fluorouracil toxicity and congenital thymine uraciluria. 1994 Sep 16 1
83 1544906 Mechanism-based inactivation of dihydropyrimidine dehydrogenase by 5-ethynyluracil. 1992 Mar 15 2
84 2528450 Dihydropyrimidine dehydrogenase activity in human blood mononuclear cells. 1989 2