| 1 |
34672113 | Clinical and Preclinical Evidence for Roles of Soluble Epoxide Hydrolase in Osteoarthritis Knee Pain. | 2022 Apr |
4 |
| 2 |
34922004 | The soluble epoxide hydrolase inhibitor GSK2256294 decreases the proportion of adipose pro-inflammatory T cells. | 2022 Feb |
3 |
| 3 |
35183688 | A hypothesis-driven study to comprehensively investigate the association between genetic polymorphisms in EPHX2 gene and cardiovascular diseases: Findings from the UK Biobank. | 2022 May 15 |
3 |
| 4 |
35229747 | Epoxyeicosatrienoic acids and soluble epoxide hydrolase in physiology and diseases of the central nervous system. | 2022 Jan-Feb |
5 |
| 5 |
33369424 | Discovery of Soluble Epoxide Hydrolase Inhibitors from Chemical Synthesis and Natural Products. | 2021 Jan 14 |
1 |
| 6 |
33788190 | Roles of Genetic Predisposition in the Sex Bias of Pulmonary Pathophysiology, as a Function of Estrogens : Sex Matters in the Prevalence of Lung Diseases. | 2021 |
3 |
| 7 |
33990688 | The arachidonic acid metabolite 11,12-epoxyeicosatrienoic acid alleviates pulmonary fibrosis. | 2021 May |
2 |
| 8 |
34038767 | Genetic deficiency or pharmacological inhibition of soluble epoxide hydrolase ameliorates high fat diet-induced pancreatic β-cell dysfunction and loss. | 2021 Aug 20 |
1 |
| 9 |
34455816 | GSK2256294 Decreases sEH (Soluble Epoxide Hydrolase) Activity in Plasma, Muscle, and Adipose and Reduces F2-Isoprostanes but Does Not Alter Insulin Sensitivity in Humans. | 2021 Sep |
1 |
| 10 |
34639055 | Epoxyeicosatrienoic Acids and Fibrosis: Recent Insights for the Novel Therapeutic Strategies. | 2021 Oct 3 |
2 |
| 11 |
34817988 | New Alkoxy- Analogues of Epoxyeicosatrienoic Acids Attenuate Cisplatin Nephrotoxicity In Vitro via Reduction of Mitochondrial Dysfunction, Oxidative Stress, Mitogen-Activated Protein Kinase Signaling, and Caspase Activation. | 2021 Dec 20 |
1 |
| 12 |
32903307 | The Anti-inflammatory Effect of Soluble Epoxide Hydrolase Inhibitor and 14, 15-EET in Kawasaki Disease Through PPARγ/STAT1 Signaling Pathway. | 2020 |
2 |
| 13 |
33239900 | The Human Genetic Variants CYP2J2 rs2280275 and EPHX2 rs751141 and Risk of Diabetic Nephropathy in Egyptian Type 2 Diabetic Patients. | 2020 |
1 |
| 14 |
33255197 | Small Molecule Soluble Epoxide Hydrolase Inhibitors in Multitarget and Combination Therapies for Inflammation and Cancer. | 2020 Nov 24 |
1 |
| 15 |
33312058 | Association of the sEH gene promoter polymorphisms and haplotypes with preeclampsia. | 2020 Oct 2 |
2 |
| 16 |
33588415 | Soluble Epoxide Hydrolase as an Important Player in Intestinal Cell Differentiation. | 2020 |
1 |
| 17 |
33994786 | Missense Genetic Polymorphisms of Microsomal (EPHX1) and Soluble Epoxide Hydrolase (EPHX2) and Their Relation to the Risk of Large Artery Atherosclerotic Ischemic Stroke in a Turkish Population. | 2020 |
2 |
| 18 |
30447256 | Humble beginnings with big goals: Small molecule soluble epoxide hydrolase inhibitors for treating CNS disorders. | 2019 Jan |
2 |
| 19 |
30716359 | Role of epoxy-fatty acids and epoxide hydrolases in the pathology of neuro-inflammation. | 2019 Apr |
2 |
| 20 |
30885203 | Altered bioavailability of epoxyeicosatrienoic acids is associated with conduit artery endothelial dysfunction in type 2 diabetic patients. | 2019 Mar 18 |
2 |
| 21 |
31002701 | Preclinical evaluation of EPHX2 inhibition as a novel treatment for inflammatory bowel disease. | 2019 |
3 |
| 22 |
31306370 | Role of Cytochrome p450 and Soluble Epoxide Hydrolase Enzymes and Their Associated Metabolites in the Pathogenesis of Diabetic Cardiomyopathy. | 2019 Sep |
3 |
| 23 |
31622444 | Polymorphisms in vasoactive eicosanoid genes of kidney donors affect biopsy scores and clinical outcomes in renal transplantation. | 2019 |
1 |
| 24 |
29588470 | Soluble epoxide hydrolase inhibition decreases reperfusion injury after focal cerebral ischemia. | 2018 Mar 27 |
2 |
| 25 |
29717935 | Expression of soluble epoxide hydrolase in renal tubular epithelial cells regulates macrophage infiltration and polarization in IgA nephropathy. | 2018 Oct 1 |
2 |
| 26 |
29908721 | Time-dependent expression pattern of cytochrome P450 epoxygenases and soluble epoxide hydrolase in normal human placenta. | 2018 Aug |
2 |
| 27 |
29960002 | Expression of cytochrome P450 epoxygenases and soluble epoxide hydrolase is regulated by hypolipidemic drugs in dose-dependent manner. | 2018 Sep 15 |
2 |
| 28 |
28218273 | Discovery of the first dual inhibitor of the 5-lipoxygenase-activating protein and soluble epoxide hydrolase using pharmacophore-based virtual screening. | 2017 Feb 20 |
2 |
| 29 |
28839250 | Pharmacological profile and efficiency in vivo of diflapolin, the first dual inhibitor of 5-lipoxygenase-activating protein and soluble epoxide hydrolase. | 2017 Aug 24 |
2 |
| 30 |
28958841 | Effects of dronedarone, amiodarone and their active metabolites on sequential metabolism of arachidonic acid to epoxyeicosatrienoic and dihydroxyeicosatrienoic acids. | 2017 Dec 15 |
2 |
| 31 |
29138698 | Soluble Epoxide Hydrolase Inhibitor and 14,15-Epoxyeicosatrienoic Acid-Facilitated Long-Term Potentiation through cAMP and CaMKII in the Hippocampus. | 2017 |
2 |
| 32 |
29285425 | Active maintenance of endothelial cells prevents kidney fibrosis. | 2017 Dec |
2 |
| 33 |
26747234 | Cyclooxygenase- and cytochrome P450-derived eicosanoids in stroke. | 2016 Jan |
1 |
| 34 |
27079253 | 11,12-Epoxyecosatrienoic acids mitigate endothelial dysfunction associated with estrogen loss and aging: Role of membrane depolarization. | 2016 May |
2 |
| 35 |
27092411 | Discovery of enantioselectivity of urea inhibitors of soluble epoxide hydrolase. | 2016 Jul 19 |
2 |
| 36 |
27144772 | Soluble Epoxide Hydrolase as a Potential Key Factor for Human Prenatal Development. | 2016 |
2 |
| 37 |
27184755 | EETs/sEH in diabetes and obesity-induced cardiovascular diseases. | 2016 Sep |
2 |
| 38 |
27372879 | Possible role of Epoxyeicosatrienoic acid in prevention of oxidative stress mediated neuroinflammation in Parkinson disorders. | 2016 Aug |
1 |
| 39 |
27924507 | TPPU protects tau from H2O2-induced hyperphosphorylation in HEK293/tau cells by regulating PI3K/AKT/GSK-3β pathway. | 2016 Dec |
2 |
| 40 |
24040964 | Influence of inflammation on cardiovascular protective effects of cytochrome P450 epoxygenase-derived epoxyeicosatrienoic acids. | 2014 Feb |
2 |
| 41 |
24691274 | An omega-3 epoxide of docosahexaenoic acid lowers blood pressure in angiotensin-II-dependent hypertension. | 2014 Jul |
2 |
| 42 |
25024195 | Dual inhibition of cyclooxygenase-2 and soluble epoxide hydrolase synergistically suppresses primary tumor growth and metastasis. | 2014 Jul 29 |
1 |
| 43 |
25406731 | Elevated 14,15- epoxyeicosatrienoic acid by increasing of cytochrome P450 2C8, 2C9 and 2J2 and decreasing of soluble epoxide hydrolase associated with aggressiveness of human breast cancer. | 2014 Nov 18 |
2 |
| 44 |
22525341 | A potent soluble epoxide hydrolase inhibitor, t-AUCB, acts through PPARγ to modulate the function of endothelial progenitor cells from patients with acute myocardial infarction. | 2013 Aug 20 |
1 |
| 45 |
23020295 | Impact of soluble epoxide hydrolase and epoxyeicosanoids on human health. | 2013 |
2 |
| 46 |
23237835 | Synthesis and structure-activity relationship of piperidine-derived non-urea soluble epoxide hydrolase inhibitors. | 2013 Jan 15 |
2 |
| 47 |
23701967 | Soluble epoxide hydrolase: gene structure, expression and deletion. | 2013 Sep 10 |
1 |
| 48 |
23853671 | Mechanism of the sex difference in endothelial dysfunction after stroke. | 2013 Aug |
2 |
| 49 |
22641086 | Mechanism of the sex difference in neuronal ischemic cell death. | 2012 Sep 6 |
1 |
| 50 |
22848834 | Anti-inflammatory effects of epoxyeicosatrienoic acids. | 2012 |
2 |