Androstenedione

cytochrome P450 family 19 subfamily A member 1 ; Homo sapiens







92 Article(s)
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1 34095690 19-hydroxy Steroids in the Aromatase Reaction: Review on Expression and Potential Functions. 2021 Jul 1 1
2 32464592 Conformational selection is present in ligand binding to cytochrome P450 19A1 lipoprotein nanodiscs. 2020 Aug 1
3 32698066 Effector role of cytochrome P450 reductase for androstenedione binding to human aromatase. 2020 Dec 1 1
4 32761874 Quantification of aromatase binding in the female human brain using [11 C]cetrozole positron emission tomography. 2020 Nov 1
5 32786398 Dynamics and Mechanism of Binding of Androstenedione to Membrane-Associated Aromatase. 2020 Aug 25 1
6 30118172 Synthetic isoflavones and doping: A novel class of aromatase inhibitors? 2019 Feb 1
7 31734656 Effect of letrozole on spermogram parameters and hormonal profile in infertile men: A clinical trial study. 2019 Oct 1 1
8 29476820 Testosterone complex and non-steroidal ligands of human aromatase. 2018 Jul 2
9 28423275 Single or Multiple Access Channels to the CYP450s Active Site? An Answer from Free Energy Simulations of the Human Aromatase Enzyme. 2017 May 4 1
10 28429243 SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway. 2017 Jul 1
11 28970799 Altered CYP19A1 and CYP3A4 Activities Due to Mutations A115V, T142A, Q153R and P284L in the Human P450 Oxidoreductase. 2017 1
12 26526982 Modulation of expression of 17-Hydroxylase/17,20 lyase (CYP17) and P450 aromatase (CYP19) by inhibition of MEK1 in a human ovarian granulosa-like tumor cell line. 2016 1
13 26096372 QM/MM modeling of the hydroxylation of the androstenedione substrate catalyzed by cytochrome P450 aromatase (CYP19A1). 2015 Sep 5 1
14 26361012 Evolutionary comparisons predict that dimerization of human cytochrome P450 aromatase increases its enzymatic activity and efficiency. 2015 Nov 2
15 26535448 Modelling inhibition of avian aromatase by azole pesticides. 2015 1
16 24630560 Inhibitory effect of Rhus verniciflua Stokes extract on human aromatase activity; butin is its major bioactive component. 2014 Apr 1 1
17 24705958 Development of an LC-MS/MS method for aromatase inhibitor screening. 2014 May 1
18 24725461 Articular cartilage chondrocytes express aromatase and use enzymes involved in estrogen metabolism. 2014 Apr 11 1
19 24782009 The endocrinology of the menstrual cycle. 2014 1
20 25226294 Use of aromatase inhibitors in large cell calcifying sertoli cell tumors: effects on gynecomastia, growth velocity, and bone age. 2014 Dec 1
21 25243857 Mechanism of inhibition of estrogen biosynthesis by azole fungicides. 2014 Dec 2
22 23450050 Interleukin-4 and prostaglandin E2 synergistically up-regulate 3β-hydroxysteroid dehydrogenase type 2 in endometrioma stromal cells. 2013 Apr 1
23 22350385 Steroidal metabolites transformed by Marchantia polymorpha cultures block breast cancer estrogen biosynthesis. 2012 May 1
24 21047944 Aromatase is increased in astrocytes in the presence of elevated pressure. 2011 Jan 1
25 21514383 Evolutionary origins of the estrogen signaling system: insights from amphioxus. 2011 Nov 2
26 21615185 Temperature derivative spectroscopy to monitor the autoxidation decay of cytochromes P450. 2011 Jul 1 1
27 22001251 Halowax 1051 affects steroidogenesis, 17β-hydroxysteroid dehydrogenase (17β-HSD) and cytochrome P450arom (CYP19) activity, and protein expression in porcine ovarian follicles. 2011 Dec 1
28 19808095 X-ray structure of human aromatase reveals an androgen-specific active site. 2010 Feb 28 1
29 20205115 Aromatase research and its clinical significance. 2010 Jan-Feb 1
30 21054398 Molecular docking and QSAR studies of aromatase inhibitor androstenedione derivatives. 2010 Dec 1
31 18817841 Estrogen formation in endometrial and cervix cancer cell lines: involvement of aromatase, steroid sulfatase and 17beta-hydroxysteroid dehydrogenases (types 1, 5, 7 and 12). 2009 Mar 25 1
32 19500885 An efficient steroid pharmacophore-based strategy to identify new aromatase inhibitors. 2009 Oct 1
33 19591804 The critical iron-oxygen intermediate in human aromatase. 2009 Sep 11 2
34 19745796 Endometriosis and the role of reproductive medicine. 2009 Aug 1
35 18482580 The ferrous-oxy complex of human aromatase. 2008 Jul 25 1
36 17066438 5Alpha-reductase type 1 and aromatase in breast carcinoma as regulators of in situ androgen production. 2007 Jan 15 2
37 17404019 Aromatase expression was not detected by immunohistochemistry in endometrial cancer. 2007 Jan 1
38 17482958 CYP19 TCT tri-nucleotide Del/Del genotype is a susceptibility marker for prostate cancer in a Taiwanese population. 2007 May 1
39 17507620 Polymorphisms in the CYP19A1 (aromatase) gene and endometrial cancer risk in Chinese women. 2007 May 2
40 17583493 A three-dimensional model of CYP19 aromatase for structure-based drug design. 2007 Jun-Jul 2
41 17595315 Modulation of human CYP19A1 activity by mutant NADPH P450 oxidoreductase. 2007 Oct 1
42 17904790 Aromatase inhibitor and bone. 2007 Oct 1
43 16386416 Aromatase-independent testosterone conversion into estrogenic steroids is inhibited by a 5 alpha-reductase inhibitor. 2006 Feb 1
44 16634644 Raman evidence for specific substrate-induced structural changes in the heme pocket of human cytochrome P450 aromatase during the three consecutive oxygen activation steps. 2006 May 2 3
45 16641167 Aromatase expression in endometriotic tissues and cell cultures of patients with endometriosis. 2006 Jun 1
46 16755025 Gas chromatography-mass spectrometric study of 19-oxygenation of the aromatase inhibitor 19-methylandrostenedione with human placental microsomes. 2006 Jun 2
47 15800924 CYP19 (aromatase) haplotypes and endometrial cancer risk. 2005 Aug 20 2
48 16002112 Gas chromatography-mass spectrometric analysis of oxidative reactions of [19,19-(2)H(2)]19-hydroxy-3-deoxy androgens by placental aromatase. bsence of a deuterium-isotope effect. 2005 Nov 1
49 16033851 Dual inhibition of mTOR and estrogen receptor signaling in vitro induces cell death in models of breast cancer. 2005 Jul 15 3
50 16086586 Aromatase reaction of 3-deoxyandrogens: steric mode of the C-19 oxygenation and cleavage of the C10-C19 bond by human placental aromatase. 2005 Aug 16 1