candesartan

angiotensin II receptor, type 1a ; Rattus norvegicus







89 Article(s)
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1 33084079 Development of a novel [18 F]fluorobenzyl derivative of the AT1 receptor antagonist Candesartan. 2021 Mar 1
2 33798796 Evaluation of the high affinity [18F]fluoropyridine-candesartan in rats for PET imaging of renal AT1 receptors. 2021 May-Jun 2
3 34012397 Amphetamine Induces Oxidative Stress, Glial Activation and Transient Angiogenesis in Prefrontal Cortex via AT1-R. 2021 1
4 32807174 Angiotensin AT1 and AT2 receptor heteromer expression in the hemilesioned rat model of Parkinson's disease that increases with levodopa-induced dyskinesia. 2020 Aug 17 2
5 32898417 TLR4/MyD88/NF-κB Signaling in the Rostral Ventrolateral Medulla Is Involved in the Depressor Effect of Candesartan in Stress-Induced Hypertensive Rats. 2020 Oct 7 1
6 30842613 Central blockade of the AT1 receptor attenuates pressor effects via reduction of glutamate release and downregulation of NMDA/AMPA receptors in the rostral ventrolateral medulla of rats with stress-induced hypertension. 2019 Aug 1
7 28215000 Angiotensin II Receptor Blockers Attenuate Lipopolysaccharide-Induced Memory Impairment by Modulation of NF-κB-Mediated BDNF/CREB Expression and Apoptosis in Spontaneously Hypertensive Rats. 2018 Feb 5
8 28884281 Angiotensin Receptor Blockade by Inhibiting Glial Activation Promotes Hippocampal Neurogenesis Via Activation of Wnt/β-Catenin Signaling in Hypertension. 2018 Jun 1
9 29902505 Short-term Heat Exposure Promotes Hippocampal Neurogenesis via Activation of Angiotensin II Type 1 Receptor in Adult Rats. 2018 Aug 10 2
10 30103772 RAS modulation prevents progressive cognitive impairment after experimental stroke: a randomized, blinded preclinical trial. 2018 Aug 13 2
11 30547063 Dataset on significant role of Candesartan on cognitive functions in rats having memory impairment induced by electromagnetic waves. 2018 Dec 1
12 27856342 Angiotensin II AT1 receptors mediate neuronal sensitization and sustained blood pressure response induced by a single injection of amphetamine. 2017 Jan 6 1
13 28468966 Protein disulfide isomerase regulates renal AT1 receptor function and blood pressure in rats. 2017 Aug 1 2
14 27199659 Surgery-Induced Hippocampal Angiotensin II Elevation Causes Blood-Brain Barrier Disruption via MMP/TIMP in Aged Rats. 2016 1
15 27531064 Mechanical activation of angiotensin II type 1 receptors causes actin remodelling and myogenic responsiveness in skeletal muscle arterioles. 2016 Dec 1 1
16 27889505 Candesartan ameliorates arsenic-induced hypertensive vascular remodeling by regularizing angiotensin II and TGF-beta signaling in rats. 2016 Dec 30 2
17 24464858 Beneficial effect of candesartan and lisinopril against haloperidol-induced tardive dyskinesia in rat. 2015 Dec 1
18 25084762 Low-dose candesartan enhances molecular mediators of neuroplasticity and subsequent functional recovery after ischemic stroke in rats. 2015 2
19 25687731 Oxidative stress causes imbalance of renal renin angiotensin system (RAS) components and hypertension in obese Zucker rats. 2015 Feb 16 1
20 25707593 Prorenin stimulates a pro-angiogenic and pro-inflammatory response in retinal endothelial cells and an M1 phenotype in retinal microglia. 2015 May 1
21 25986885 Dopamine D2 and angiotensin II type 1 receptors form functional heteromers in rat striatum. 2015 Jul 15 1
22 23973568 Effect of chronic treatment with angiotensin type 1 receptor antagonists on striatal dopamine levels in normal rats and in a rat model of Parkinson's disease treated with L-DOPA. 2014 Jan 1
23 24814703 Prophylactic angiotensin type 1 receptor antagonism confers neuroprotection in an aged rat model of postoperative cognitive dysfunction. 2014 Jun 20 1
24 24847907 Mitochondrial KATP channel involvement in angiotensin II-induced autophagy in vascular smooth muscle cells. 2014 Jul 2
25 25326022 Candesartan attenuates ischemic brain edema and protects the blood-brain barrier integrity from ischemia/reperfusion injury in rats. 2014 1
26 25429176 Blockade of Central Angiotensin II AT1 Receptor Protects the Brain from Ischemia/Reperfusion Injury in Normotensive Rats. 2014 Nov 2
27 23816375 Role of angiotensin II type 1 receptors in the subfornical organ in the pressor responses to central sodium in rats. 2013 Aug 21 1
28 23823602 Chronic AT2 receptor activation increases renal ACE2 activity, attenuates AT1 receptor function and blood pressure in obese Zucker rats. 2013 Nov 1
29 21900450 Defective nitric oxide production impairs angiotensin II-induced Na-K-ATPase regulation in spontaneously hypertensive rats. 2012 Jan 1 1
30 22411927 Altered functioning of both renal dopamine D1 and angiotensin II type 1 receptors causes hypertension in old rats. 2012 May 1
31 20936684 The AT₁ angiotensin II receptor blockade attenuates the development of amphetamine-induced behavioral sensitization in a two-injection protocol. 2011 Jun 1
32 21303953 Angiotensin III stimulates aldosterone secretion from adrenal gland partially via angiotensin II type 2 receptor but not angiotensin II type 1 receptor. 2011 Apr 2
33 21846363 Renin angiotensin system and gender differences in dopaminergic degeneration. 2011 Aug 16 1
34 19907343 Renal vasoconstrictor and pressor responses to angiotensin IV in mice are AT1a-receptor mediated. 2010 Mar 1
35 20001455 The mechanism of distinct diurnal variations of renin-angiotensin system in aorta and heart of spontaneously hypertensive rats. 2009 Nov 2
36 17962624 The mechanistic basis for the disparate effects of angiotensin II on coronary collateral growth. 2008 Jan 1
37 18498681 Angiotensin II type 1 receptors may not influence response of spinal autonomic neurons to axonal damage. 2008 Sep 1
38 18650791 Candesartan suppresses chronic renal inflammation by a novel antioxidant action independent of AT1R blockade. 2008 Nov 1
39 18955661 Loss of biphasic effect on Na/K-ATPase activity by angiotensin II involves defective angiotensin type 1 receptor-nitric oxide signaling. 2008 Dec 1
40 16838106 Transient receptor potential (TRP) protein 7 acts as a G protein-activated Ca2+ channel mediating angiotensin II-induced myocardial apoptosis. 2007 Jan 1
41 17032940 Candesartan prevents long-term impairment of renal function in response to neonatal partial unilateral ureteral obstruction. 2007 Feb 1
42 17185407 AT(1) and glutamatergic receptors in paraventricular nucleus support blood pressure during water deprivation. 2007 Apr 1
43 17284329 AT1 receptor blocker-insensitive mutant AT1A angiotensin receptors reveal the presence of G protein-independent signaling in C9 cells. 2007 May 15 1
44 17855497 Baroreceptor reflex modulation by circulating angiotensin II is mediated by AT1 receptors in the nucleus tractus solitarius. 2007 Dec 2
45 16210417 Blockade of AT1 receptors in the rostral ventrolateral medulla increases sympathetic activity under hypoxic conditions. 2006 Mar 1
46 16601219 AT1 receptor blockade regulates the local angiotensin II system in cerebral microvessels from spontaneously hypertensive rats. 2006 May 1
47 16601566 Angiotensin II: multitasking in the brain. 2006 Mar 2
48 16807546 Long-term regulation of proximal tubule acid-base transporter abundance by angiotensin II. 2006 Aug 1
49 15685215 Evidence for a functional cardiac interaction between losartan and angiotensin-(1-7) receptors revealed by orthostatic tilting test in rats. 2005 Mar 1
50 16298685 Activation of AP-1 through reactive oxygen species by angiotensin II in rat cardiomyocytes. 2005 Dec 15 1