Fatty Acids, Unsaturated

fatty acid desaturase 1 ; Homo sapiens







36 Article(s)
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1 34997498 The dysregulation of unsaturated fatty acid-based metabolomics in the MNNG-induced malignant transformation of Het-1A cells. 2022 Apr 2
2 35548952 FADS1 overexpression promotes fatty acid synthesis and triacylglycerol accumulation via inhibiting the AMPK/SREBP1 pathway in goat mammary epithelial cells. 2022 May 23 8
3 35631303 Investigation of Maternal Diet and FADS1 Polymorphism Associated with Long-Chain Polyunsaturated Fatty Acid Compositions in Human Milk. 2022 May 23 1
4 33310680 Differences in erythrocyte phospholipid membrane long-chain polyunsaturated fatty acids and the prevalence of fatty acid desaturase genotype among African Americans and European Americans. 2021 Jan 1
5 33331250 Association between FADS1 rs174547 and levels of long-chain PUFA: a meta-analysis. 2021 Oct 28 3
6 33530084 Genetic Variation, Diet, Inflammation, and the Risk for COVID-19. 2021 1
7 34059134 Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches. 2021 May 31 1
8 34143495 Relaxin has beneficial effects on liver lipidome and metabolic enzymes. 2021 Jul 1
9 34438249 Delta-5-desaturase: A novel therapeutic target for cancer management. 2021 Nov 1
10 35211495 Interpreting Clinical Trials With Omega-3 Supplements in the Context of Ancestry and FADS Genetic Variation. 2021 1
11 32186652 Association of FADS1/2 Locus Variants and Polyunsaturated Fatty Acids With Aortic Stenosis. 2020 Jun 1 1
12 32332698 FADS1 promotes the progression of laryngeal squamous cell carcinoma through activating AKT/mTOR signaling. 2020 Apr 24 4
13 32534376 Fatty acid desaturation in red blood cell membranes of patients with type 2 diabetes is improved by zinc supplementation. 2020 Dec 2
14 32731631 Desaturase Activity and the Risk of Type 2 Diabetes and Coronary Artery Disease: A Mendelian Randomization Study. 2020 Jul 28 4
15 30082751 FADS1 genotype is distinguished by human subcutaneous adipose tissue fatty acids, but not inflammatory gene expression. 2019 Aug 2
16 30535058 The Association of Polyunsaturated Fatty Acid δ-5-Desaturase Activity with Risk Factors for Type 2 Diabetes Is Dependent on Plasma ApoB-Lipoproteins in Overweight and Obese Adults. 2019 Jan 1 1
17 30943390 Fatty Acid Desaturation Gets a NAD+ Reputation. 2019 Apr 2 1
18 28774683 Dietary linoleic acid interacts with FADS1 genetic variability to modulate HDL-cholesterol and obesity-related traits. 2018 Oct 5
19 29549917 Associations among FADS1 rs174547, eicosapentaenoic acid/arachidonic acid ratio, and arterial stiffness in overweight subjects. 2018 Mar 1
20 30170993 Identification of a functional FADS1 3'UTR variant associated with erythrocyte n-6 polyunsaturated fatty acids levels. 2018 Sep - Oct 4
21 26501394 Gene-diet interaction of a common FADS1 variant with marine polyunsaturated fatty acids for fatty acid composition in plasma and erythrocytes among men. 2016 Feb 1
22 25646338 Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. 2015 Feb 1
23 25755223 Polyunsaturated fatty acid regulation of adipocyte FADS1 and FADS2 expression and function. 2015 Apr 3
24 24460221 Unsaturated fatty acids, desaturases, and human health. 2014 Feb 2
25 24167612 Gene expression of desaturase (FADS1 and FADS2) and Elongase (ELOVL5) enzymes in peripheral blood: association with polyunsaturated fatty acid levels and atopic eczema in 4-year-old children. 2013 1
26 22123669 Recent insights into the relation of Δ5 desaturase and Δ6 desaturase activity to the development of type 2 diabetes. 2012 Feb 2
27 22803604 Nutritional aspects of epigenetic inheritance. 2012 Aug 2
28 22140540 FADS2 function loss at the cancer hotspot 11q13 locus diverts lipid signaling precursor synthesis to unusual eicosanoid fatty acids. 2011 1
29 19752397 The fatty acid desaturase 3 gene encodes for different FADS3 protein isoforms in mammalian tissues. 2010 Mar 2
30 20045144 Role of FADS1 and FADS2 polymorphisms in polyunsaturated fatty acid metabolism. 2010 Jul 1
31 20364269 A single nucleotide polymorphism in the FADS1/FADS2 gene is associated with plasma lipid profiles in two genetically similar Asian ethnic groups with distinctive differences in lifestyle. 2010 Jun 2
32 20484448 Dietary n-3 and n-6 polyunsaturated fatty acid intake interacts with FADS1 genetic variation to affect total and HDL-cholesterol concentrations in the Doetinchem Cohort Study. 2010 Jul 2
33 20948998 Variants of the FADS1 FADS2 gene cluster, blood levels of polyunsaturated fatty acids and eczema in children within the first 2 years of life. 2010 Oct 11 1
34 18320251 SNPs of the FADS gene cluster are associated with polyunsaturated fatty acids in a cohort of patients with cardiovascular disease. 2008 Apr 2
35 18842780 FADS genotypes and desaturase activity estimated by the ratio of arachidonic acid to linoleic acid are associated with inflammation and coronary artery disease. 2008 Oct 2
36 8489510 Alternative route for the biosynthesis of polyunsaturated fatty acids in K562 cells. 1993 May 1 1