| 1 |
34718859 | FADS1 rs174550 genotype and high linoleic acid diet modify plasma PUFA phospholipids in a dietary intervention study. | 2022 Mar |
3 |
| 2 |
34937850 | New understandings of the pathway of long-chain polyunsaturated fatty acid biosynthesis. | 2022 Mar 1 |
3 |
| 3 |
35490599 | Statin therapy upregulates arachidonic acid status via enhanced endogenous synthesis in patients with plaque psoriasis. | 2022 May |
1 |
| 4 |
33530084 | Genetic Variation, Diet, Inflammation, and the Risk for COVID-19. | 2021 |
1 |
| 5 |
34535685 | Iminodibenzyl induced redirected COX-2 activity inhibits breast cancer progression. | 2021 Sep 17 |
1 |
| 6 |
34836252 | Genomics of Postprandial Lipidomics in the Genetics of Lipid-Lowering Drugs and Diet Network Study. | 2021 Nov 10 |
1 |
| 7 |
32332698 | FADS1 promotes the progression of laryngeal squamous cell carcinoma through activating AKT/mTOR signaling. | 2020 Apr 24 |
2 |
| 8 |
32682282 | Genetic variants in FADS1 and ELOVL2 increase level of arachidonic acid and the risk of Alzheimer's disease in the Tunisian population. | 2020 Sep |
1 |
| 9 |
30384258 | Dihomo-γ-linolenic acid inhibits growth of xenograft tumors in mice bearing human pancreatic cancer cells (BxPC-3) transfected with delta-5-desaturase shRNA. | 2019 Jan |
2 |
| 10 |
31589250 | Human milk fatty acid composition is associated with dietary, genetic, sociodemographic, and environmental factors in the CHILD Cohort Study. | 2019 Dec 1 |
2 |
| 11 |
29514873 | Multiplex genomewide association analysis of breast milk fatty acid composition extends the phenotypic association and potential selection of FADS1 variants to arachidonic acid, a critical infant micronutrient. | 2018 Jul |
2 |
| 12 |
29549917 | Associations among FADS1 rs174547, eicosapentaenoic acid/arachidonic acid ratio, and arterial stiffness in overweight subjects. | 2018 Mar |
1 |
| 13 |
29587668 | Knockdown delta-5-desaturase in breast cancer cells that overexpress COX-2 results in inhibition of growth, migration and invasion via a dihomo-γ-linolenic acid peroxidation dependent mechanism. | 2018 Mar 27 |
1 |
| 14 |
29886893 | A rare eicosanoid precursor analogue, sciadonic acid (5Z,11Z,14Z-20:3), detected in vivo in hormone positive breast cancer tissue. | 2018 Jul |
1 |
| 15 |
30170993 | Identification of a functional FADS1 3'UTR variant associated with erythrocyte n-6 polyunsaturated fatty acids levels. | 2018 Sep - Oct |
1 |
| 16 |
27276431 | Reduction of Arachidonate Is Associated With Increase in B-Cell Activation Marker in Infants: A Randomized Trial. | 2017 Mar |
2 |
| 17 |
27101738 | Knockdown of delta-5-desaturase promotes the anti-cancer activity of dihomo-γ-linolenic acid and enhances the efficacy of chemotherapy in colon cancer cells expressing COX-2. | 2016 Jul |
2 |
| 18 |
27660693 | T-3364366 Targets the Desaturase Domain of Delta-5 Desaturase with Nanomolar Potency and a Multihour Residence Time. | 2016 Sep 8 |
2 |
| 19 |
25646338 | Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. | 2015 Feb |
1 |
| 20 |
26092623 | Lipidomic analysis reveals a radiosensitizing role of gamma-linolenic acid in glioma cells. | 2015 Sep |
1 |
| 21 |
24022589 | Interaction of fatty acid genotype and diet on changes in colonic fatty acids in a Mediterranean diet intervention study. | 2013 Nov |
1 |
| 22 |
22796714 | L-Carnitine prevents the development of ventricular fibrosis and heart failure with preserved ejection fraction in hypertensive heart disease. | 2012 Sep |
1 |
| 23 |
21106917 | Genetic variants of the fatty acid desaturase gene cluster predict amounts of red blood cell docosahexaenoic and other polyunsaturated fatty acids in pregnant women: findings from the Avon Longitudinal Study of Parents and Children. | 2011 Jan |
1 |
| 24 |
21413848 | Insulin induces fatty acid desaturase expression in human monocytes. | 2011 Jul |
1 |
| 25 |
20687342 | [Effect of Mortierlla isabellina delta5-desaturases gene on arachidonic acid synthesis]. | 2010 Jun |
3 |
| 26 |
19148276 | Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study. | 2009 Jan |
1 |
| 27 |
18320251 | SNPs of the FADS gene cluster are associated with polyunsaturated fatty acids in a cohort of patients with cardiovascular disease. | 2008 Apr |
1 |
| 28 |
18842780 | FADS genotypes and desaturase activity estimated by the ratio of arachidonic acid to linoleic acid are associated with inflammation and coronary artery disease. | 2008 Oct |
1 |
| 29 |
16462894 | Effect of geraniol on fatty-acid and mevalonate metabolism in the human hepatoma cell line Hep G2. | 2006 Feb |
1 |
| 30 |
16201244 | [Isolation and functional identification of delta 5 desaturase gene from Mortierella alpina]. | 2005 Sep |
2 |
| 31 |
14717057 | Plasma fatty acid composition and incidence of coronary heart disease in middle aged adults: the Atherosclerosis Risk in Communities (ARIC) Study. | 2003 Oct |
1 |
| 32 |
12440976 | Gene regulation of mammalian desaturases. | 2002 Nov |
1 |
| 33 |
10769175 | cDNA cloning and characterization of human Delta5-desaturase involved in the biosynthesis of arachidonic acid. | 2000 May 1 |
1 |
| 34 |
6961441 | Development and characterization of a tissue culture cell line with essential fatty acid deficiency. | 1982 Dec |
1 |