Hypochlorous Acid

myeloperoxidase ; Homo sapiens







637 Article(s)
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401 12033452 Human neutrophils oxidize low-density lipoprotein by a hypochlorous acid-dependent mechanism: the role of vitamin C. 2002 Mar-Apr 3
402 12034845 Novel products generated from 2'-deoxyguanosine by hypochlorous acid or a myeloperoxidase-H2O2-Cl- system: identification of diimino-imidazole and amino-imidazolone nucleosides. 2002 Jun 1 2
403 12054473 Hydrogen peroxide-induced apoptosis of HL-60 human leukemia cells is mediated by the oxidants hypochlorous acid and chloramines. 2002 May 15 2
404 12060654 Human neutrophils use the myeloperoxidase-hydrogen peroxide-chloride system to chlorinate but not nitrate bacterial proteins during phagocytosis. 2002 Aug 23 1
405 12070141 Hypochlorite-modified high density lipoprotein, a high affinity ligand to scavenger receptor class B, type I, impairs high density lipoprotein-dependent selective lipid uptake and reverse cholesterol transport. 2002 Aug 30 1
406 12208372 Eosinophil peroxidase produces hypobromous acid in the airways of stable asthmatics. 2002 Sep 15 1
407 12214562 Differences in the accumulation of ascorbic acid in normal, myeloperoxidase deficient and NADPH-oxidase deficient granulocytes. 2002 Jul 1
408 12221280 Inhibition of hypochlorous acid-induced cellular toxicity by nitrite. 2002 Sep 17 2
409 12223088 Interaction of exogenous hypochlorite or hypochlorite produced by myeloperoxidase + H2O2 + Cl- system with unsaturated phosphatidylcholines. 2002 Aug 4
410 12372420 Nitration and chlorination of folic acid by peroxynitrite and hypochlorous acid, and the selective binding of 10-nitro-folate to folate receptor beta. 2002 Oct 11 1
411 12377783 Identification in human atherosclerotic lesions of GA-pyridine, a novel structure derived from glycolaldehyde-modified proteins. 2002 Dec 13 1
412 12454302 Effect of arachidonic and eicosapentaenoic acids on acute lung injury induced by hypochlorous acid. 2002 Dec 2
413 12505315 Biological reactivity and biomarkers of the neutrophil oxidant, hypochlorous acid. 2002 Dec 27 3
414 11054430 The nitric oxide congener nitrite inhibits myeloperoxidase/H2O2/ Cl- -mediated modification of low density lipoprotein. 2001 Jan 19 4
415 11096071 Production of brominating intermediates by myeloperoxidase. A transhalogenation pathway for generating mutagenic nucleobases during inflammation. 2001 Mar 16 1
416 11168995 Role of oxidized low-density lipoprotein in the atherosclerosis of uremia. 2001 Feb 2
417 11172805 p-Hydroxyphenylacetaldehyde, the major product of tyrosine oxidation by the activated myeloperoxidase system can act as an antioxidant in LDL. 2001 Feb 9 1
418 11182523 Relative reactivities of N-chloramines and hypochlorous acid with human plasma constituents. 2001 Mar 1 2
419 11238037 Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes. 2001 Mar 3
420 11278358 Hypochlorite-modified low density lipoprotein inhibits nitric oxide synthesis in endothelial cells via an intracellular dislocalization of endothelial nitric-oxide synthase. 2001 Apr 27 2
421 11297432 Hypochlorous acid produced by the myeloperoxidase system of human phagocytes induces covalent cross-links between DNA and protein. 2001 Mar 27 4
422 11304574 Myeloperoxidase-dependent generation of hypochlorite-modified proteins in human placental tissues during normal pregnancy. 2001 Apr 9
423 11378533 Effects of hypochlorite on cultured respiratory epithelial cells. 2001 May 1
424 11422382 Human neutrophils employ the myeloperoxidase/hydrogen peroxide/chloride system to oxidatively damage apolipoprotein A-I. 2001 Jun 2
425 11425491 Comparison of low-density lipoprotein modification by myeloperoxidase-derived hypochlorous and hypobromous acids. 2001 Jul 1 1
426 11440179 Chlorination of N-acetyltyrosine with HOCl, chloramines, and myeloperoxidase-hydrogen peroxide-chloride system. 2001 1
427 11505786 Chlorite-hemoprotein interaction as key role for the pharmacological activity of the chlorite-based drug WF10. 2001 1
428 11511181 Hypochlorite-induced damage to nucleosides: formation of chloramines and nitrogen-centered radicals. 2001 Aug 2
429 11513598 A kinetic analysis of the catalase activity of myeloperoxidase. 2001 Aug 28 1
430 11515815 The physiological role and pharmacological potential of nitric oxide in neutrophil activation. 2001 Aug 2
431 11533038 Hypochlorous acid oxygenates the cysteine switch domain of pro-matrilysin (MMP-7). A mechanism for matrix metalloproteinase activation and atherosclerotic plaque rupture by myeloperoxidase. 2001 Nov 2 3
432 11533049 Chlorination of guanosine and other nucleosides by hypochlorous acid and myeloperoxidase of activated human neutrophils. Catalysis by nicotine and trimethylamine. 2001 Nov 2 1
433 11559029 Formation of spiroiminodihydantoin nucleoside by reaction of 8-oxo-7,8-dihydro-2'-deoxyguanosine with hypochlorous acid or a myeloperoxidase-H(2)O(2)-Cl(-) system. 2001 Sep 3
434 11566022 Hypochlorous acid stimulation of the mitogen-activated protein kinase pathway enhances cell survival. 2001 Oct 1 2
435 11589706 Redox properties of the couple compound I/native enzyme of myeloperoxidase and eosinophil peroxidase. 2001 Oct 1
436 11594512 Neutrophil functions of patients with vasculitis related to myeloperoxidase-specific anti-neutrophil antibody. 2001 Aug 1
437 11677044 Effects of hypochlorous acid on unsaturated phosphatidylcholines. 2001 Nov 1 1
438 11697850 Hypochlorite- and hypobromite-mediated radical formation and its role in cell lysis. 2001 Nov 15 1
439 11705694 Myeloperoxidase-catalyzed 3-chlorotyrosine formation in dialysis patients. 2001 Nov 15 2
440 11714858 Selective oxidation in vitro by myeloperoxidase of the N-terminal amine in apolipoprotein B-100. 2001 Nov 1
441 11733358 Immunohistochemical detection of myeloperoxidase and its oxidation products in Kupffer cells of human liver. 2001 Dec 1
442 11738154 Plasma concentration of myeloperoxidase enzyme in pre- and post-climacterial people: related superoxide anion generation. 2001 Dec 1
443 11742862 Myeloperoxidase and hypochlorite, but not copper ions, oxidize heparin-bound LDL particles and release them from heparin. 2001 Dec 2
444 11848478 Promyelocytic HL-60 cells induce apoptosis selectively in transformed cells: involvement of myeloperoxidase, nitric oxide and target cell-derived superoxide anions. 2001 Sep-Oct 1
445 12016330 Formation of novel bioactive metabolites from the reactions of pro-inflammatory oxidants with polyphenolics. 2001 1
446 10608505 Myeloperoxidase. 2000 Jan 1
447 10637476 Further elucidation of mechanism of resistance to vincristine in myeloid cells: role of hypochlorous acid in degradation of vincristine by myeloperoxidase. 2000 Jan 4
448 10677352 Reagent or myeloperoxidase-generated hypochlorite affects discrete regions in lipid-free and lipid-associated human apolipoprotein A-I. 2000 Mar 1 2
449 10699463 Role of TNFalpha in regulation of myeloperoxidase expression in irradiated HL60 promyelocytic cells. 2000 Feb 28 4
450 10742562 Association of a myeloperoxidase promoter polymorphism with multiple sclerosis. 2000 Jun 26 2