Hypochlorous Acid

myeloperoxidase ; Homo sapiens







637 Article(s)
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451 10754262 Pathways of phospholipid oxidation by HOCl in human LDL detected by LC-MS. 2000 Mar 1 1
452 10766781 Nitrite as a substrate and inhibitor of myeloperoxidase. Implications for nitration and hypochlorous acid production at sites of inflammation. 2000 Apr 21 1
453 10801811 Myeloperoxidase is involved in H2O2-induced apoptosis of HL-60 human leukemia cells. 2000 Jul 21 1
454 10866816 Kinetics of tryptophan oxidation in plasma lipoproteins by myeloperoxidase-generated HOCl. 2000 Jul 1
455 10880973 Immunohistochemical evidence for the myeloperoxidase/H2O2/halide system in human atherosclerotic lesions: colocalization of myeloperoxidase and hypochlorite-modified proteins. 2000 Jul 5
456 10894808 Oxidation of LDL by myeloperoxidase and reactive nitrogen species: reaction pathways and antioxidant protection. 2000 Jul 1
457 10984130 Kinetics of chlorination of monochlorodimedone by myeloperoxidase. 2000 4
458 10993479 Antioxidant binding of caeruloplasmin to myeloperoxidase: myeloperoxidase is inhibited, but oxidase, peroxidase and immunoreactive properties of caeruloplasmin remain intact. 2000 Sep 8
459 10994870 The reactivity of myeloperoxidase compound I formed with hypochlorous acid. 2000 11
460 10994871 Oxidation of tryptophan by redox intermediates of myeloperoxidase and inhibition of hypochlorous acid production. 2000 1
461 10994873 Myeloperoxidase-catalyzed chlorination of histamine by stimulated neutrophils. 2000 1
462 10994875 Transformed target cell-derived superoxide anions drive apoptosis induction by myeloperoxidase. 2000 1
463 10998045 Mechanism of reaction of myeloperoxidase with hydrogen peroxide and chloride ion. 2000 Oct 7
464 11004581 Comparison of HOCl traps with myeloperoxidase inhibitors in prevention of low density lipoprotein oxidation. 2000 Aug 31 6
465 11020661 Biomarkers of myeloperoxidase-derived hypochlorous acid. 2000 Sep 1 3
466 11237094 Hypochlorite-induced oxidation of thiols: formation of thiyl radicals and the role of sulfenyl chlorides as intermediates. 2000 Dec 2
467 11996112 The reactions of hypochlorous acid, the reactive oxygen species produced by myeloperoxidase, with lipids. 2000 5
468 9895241 Phagocytic killing of microorganisms by radical processes: consequences of the reaction of hydroxyl radicals with chloride yielding chlorine atoms. 1999 Feb 4
469 9918702 Myeloperoxidase polymorphism is associated with gender specific risk for Alzheimer's disease. 1999 Jan 2
470 10029554 8-Nitro-2'-deoxyguanosine, a specific marker of oxidation by reactive nitrogen species, is generated by the myeloperoxidase-hydrogen peroxide-nitrite system of activated human phagocytes. 1999 Feb 23 1
471 10092633 Transient and steady-state kinetics of the oxidation of substituted benzoic acid hydrazides by myeloperoxidase. 1999 Apr 2 1
472 10191293 Selective modification of apoB-100 in the oxidation of low density lipoproteins by myeloperoxidase in vitro. 1999 Apr 2
473 10215584 Secondary radicals derived from chloramines of apolipoprotein B-100 contribute to HOCl-induced lipid peroxidation of low-density lipoproteins. 1999 May 1 3
474 10222254 Loss of 3-nitrotyrosine on exposure to hypochlorous acid: implications for the use of 3-nitrotyrosine as a bio-marker in vivo. 1999 Apr 29 2
475 10333500 Hypochlorite-induced oxidation of proteins in plasma: formation of chloramines and nitrogen-centred radicals and their role in protein fragmentation. 1999 Jun 1 2
476 10393704 The myeloperoxidase system of human phagocytes generates Nepsilon-(carboxymethyl)lysine on proteins: a mechanism for producing advanced glycation end products at sites of inflammation. 1999 Jul 2
477 10430993 Neutrophils and renal failure. 1999 Aug 1
478 10482305 Quality control in the endoplasmic reticulum: lessons from hereditary myeloperoxidase deficiency. 1999 Sep 1
479 10490267 Degradation of hypochlorite-damaged glucose-6-phosphate dehydrogenase by the 20S proteasome. 1999 Sep 1
480 10516189 Loss of GSH and thiol enzymes in endothelial cells exposed to sublethal concentrations of hypochlorous acid. 1999 Oct 1
481 10527939 NADPH as a co-substrate for studies of the chlorinating activity of myeloperoxidase. 1999 Nov 1 4
482 10556685 The inhibitory effect of ambroxol on hypochlorous acid-induced tissue damage and respiratory burst of phagocytic cells. 1999 Oct 21 1
483 10559226 Molecular chlorine generated by the myeloperoxidase-hydrogen peroxide-chloride system of phagocytes produces 5-chlorocytosine in bacterial RNA. 1999 Nov 19 5
484 10784377 Correlation of low-density lipoprotein modification by myeloperoxidase with hypochlorous acid formation. 1999 2
485 17638096 Current concepts of the actions of paracetamol (acetaminophen) and NSAIDs. 1999 2
486 9478947 Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to oxidize alpha-amino acids to a family of reactive aldehydes. Mechanistic studies identifying labile intermediates along the reaction pathway. 1998 Feb 27 3
487 9618427 Effect of antithyroid drugs on hydroxyl radical formation and alpha-1-proteinase inhibitor inactivation by neutrophils: therapeutic implications. 1998 Jun 1
488 9620862 Hypochlorite-induced damage to proteins: formation of nitrogen-centred radicals from lysine residues and their role in protein fragmentation. 1998 Jun 15 2
489 9626568 Human low density lipoprotein as a target of hypochlorite generated by myeloperoxidase. 1998 May 2
490 9635031 Myeloperoxidase (MPO) may mediate neutrophil adherence to the endothelium through upregulation of CD11B expression--an effect downregulated by taurine. 1998 2
491 9799559 Hypochlorous acid activates the tumor suppressor protein p53 in cultured human skin fibroblasts. 1998 Nov 1 4
492 9022075 Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein. A mechanism for the generation of highly reactive alpha-hydroxy and alpha,beta-unsaturated aldehydes by phagocytes at sites of inflammation. 1997 Feb 1 2
493 9033274 Immunological evidence for hypochlorite-modified proteins in human kidney. 1997 Feb 3
494 9034238 Aminobenzoic acid compounds as HOCl traps for activated neutrophils. 1997 2
495 9113623 Nuclear magnetic resonance characterization of 6 alpha-chloro-5 beta-cholestane-3 beta,5-diol formed from the reaction of hypochlorous acid with cholesterol. 1997 Apr 1
496 9128147 X-ray absorption and resonance raman spectroscopy of human myeloperoxidase at neutral and acid pH. 1997 Apr 4 2
497 9151778 3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima. 1997 May 1 2
498 9259996 Pathways for oxidation of low density lipoprotein by myeloperoxidase: tyrosyl radical, reactive aldehydes, hypochlorous acid and molecular chlorine. 1997 1
499 9285242 Nitric oxide and antimicrobial activity of reactive oxygen intermediates. 1997 Aug 2
500 9307233 Immunohistochemical and genetic evidence of myeloperoxidase involvement in multiple sclerosis. 1997 Sep 2