thioflavin T

synuclein alpha ; Homo sapiens







72 Article(s)
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1 35013421 Two-step screening method to identify α-synuclein aggregation inhibitors for Parkinson's disease. 2022 Jan 10 1
2 35327661 Alpha-Synuclein-Specific Naturally Occurring Antibodies Inhibit Aggregation In Vitro and In Vivo. 2022 Mar 18 2
3 33527970 Unravelling the potency of triazole analogues for inhibiting α-synuclein fibrillogenesis and in vitro disaggregation. 2021 Feb 25 1
4 33997868 The food additive fast green FCF inhibits α-synuclein aggregation, disassembles mature fibrils and protects against amyloid-induced neurotoxicity. 2021 Jun 21 1
5 34151857 α-Synuclein Responses in the Laterodorsal Tegmentum, the Pedunculopontine Tegmentum, and the Substantia Nigra: Implications for Early Appearance of Sleep Disorders in Parkinson's Disease. 2021 1
6 34309760 A glutaminyl cyclase-catalyzed α-synuclein modification identified in human synucleinopathies. 2021 Sep 1
7 34362943 Equine pituitary pars intermedia dysfunction: a spontaneous model of synucleinopathy. 2021 Aug 6 1
8 34432157 Pharmacophore modeling and 3D-QSAR study for the design of novel α-synuclein aggregation inhibitors. 2021 Aug 25 2
9 34911929 Capillary flow experiments for thermodynamic and kinetic characterization of protein liquid-liquid phase separation. 2021 Dec 15 1
10 34948195 Ellagic Acid Prevents α-Synuclein Aggregation and Protects SH-SY5Y Cells from Aggregated α-Synuclein-Induced Toxicity via Suppression of Apoptosis and Activation of Autophagy. 2021 Dec 13 1
11 31945397 Naturally occurring cinnamic acid derivatives prevent amyloid transformation of alpha-synuclein. 2020 Mar 1
12 32013170 Amyloid-Beta Peptides Trigger Aggregation of Alpha-Synuclein In Vitro. 2020 Jan 29 1
13 32121059 Alpha-Synuclein Amyloid Aggregation Is Inhibited by Sulfated Aromatic Polymers and Pyridinium Polycation. 2020 Feb 28 1
14 32154238 Antioxidant Nanoparticles for Concerted Inhibition of α-Synuclein Fibrillization, and Attenuation of Microglial Intracellular Aggregation and Activation. 2020 1
15 32571190 α-Synuclein Overexpression in SH-SY5Y Human Neuroblastoma Cells Leads to the Accumulation of Thioflavin S-positive Aggregates and Impairment of Glycolysis. 2020 May 1
16 32579329 Dual Targeting of Monomeric Tau and α-Synuclein Aggregation: A New Multitarget Therapeutic Strategy for Neurodegeneration. 2020 Jul 15 2
17 32673279 Anti-amyloidogenic effect of artemin on α-synuclein. 2020 Sep 25 2
18 32850841 Reversal of Alpha-Synuclein Fibrillization by Protein Disulfide Isomerase. 2020 1
19 32961434 Diphenyl triazine hybrids inhibit α-synuclein fibrillogenesis: Design, synthesis and in vitro efficacy studies. 2020 Dec 1 1
20 30278239 Modulating α-synuclein fibril formation using DNA tetrahedron nanostructures. 2019 Jan 1
21 30968030 Novel Mannitol-Based Small Molecules for Inhibiting Aggregation of α-Synuclein Amyloids in Parkinson's Disease. 2019 1
22 31034772 Dissecting the Interactions between Human Serum Albumin and α-Synuclein: New Insights on the Factors Influencing α-Synuclein Aggregation in Biological Fluids. 2019 May 23 2
23 31424918 N-Terminal Acetylation Affects α-Synuclein Fibril Polymorphism. 2019 Sep 3 7
24 31695369 Cerium oxide NPs mitigate the amyloid formation of α-synuclein and associated cytotoxicity. 2019 2
25 29180135 Alpha-Synuclein transgenic mice, h-α-SynL62, display α-Syn aggregation and a dopaminergic phenotype reminiscent of Parkinson's disease. 2018 Feb 26 1
26 29577851 Structural and Aggregation Properties of Alpha-Synuclein Linked to Phospholipase A2 Action. 2018 1
27 30069495 α-Synuclein Aggregation Monitored by Thioflavin T Fluorescence Assay. 2018 Jul 20 1
28 30142878 Investigation of α-Synuclein Amyloid Fibrils Using the Fluorescent Probe Thioflavin T. 2018 Aug 23 5
29 30486688 Polymorph-specific distribution of binding sites determines thioflavin-T fluorescence intensity in α-synuclein fibrils. 2018 Sep 1
30 28292187 Distinct Mechanisms Determine α-Synuclein Fibril Morphology during Growth and Maturation. 2017 Mar 15 1
31 28640595 Detection and Characterization of Small Molecule Interactions with Fibrillar Protein Aggregates Using Microscale Thermophoresis. 2017 Sep 20 1
32 28760825 Modulation of the extent of structural heterogeneity in α-synuclein fibrils by the small molecule thioflavin T. 2017 Oct 13 1
33 26456030 Inhibition effects of tanshinone on the aggregation of α-synuclein. 2016 Jan 1
34 27965913 Blood Plasma of Patients with Parkinson's Disease Increases Alpha-Synuclein Aggregation and Neurotoxicity. 2016 1
35 28192290 Site-specific structural dynamics of α-Synuclein revealed by time-resolved fluorescence spectroscopy: a review. 2016 Oct 11 2
36 25659910 Single fibril growth kinetics of α-synuclein. 2015 Mar 27 1
37 26093169 Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration. 2015 Oct 1
38 26612754 Prion-like propagation of human brain-derived alpha-synuclein in transgenic mice expressing human wild-type alpha-synuclein. 2015 Nov 26 2
39 24460028 The presence of an air-water interface affects formation and elongation of α-Synuclein fibrils. 2014 Feb 19 1
40 24835632 Pitfalls associated with the use of Thioflavin-T to monitor anti-fibrillogenic activity. 2014 Jul 15 6
41 23333843 Nasal inoculation with α-synuclein aggregates evokes rigidity, locomotor deficits and immunity to such misfolded species as well as dopamine. 2013 Apr 15 1
42 24970188 Biophysical Characterization of α-Synuclein and Rotenone Interaction. 2013 Sep 24 2
43 22789706 Synthesis and in vitro evaluation of α-synuclein ligands. 2012 Aug 1 2
44 22986484 Correlation between protective immunity to α-synuclein aggregates, oxidative stress and inflammation. 2012 1
45 21410644 Modulation of α-synuclein aggregation by dopamine in the presence of MPTP and its metabolite. 2011 May 2
46 21848289 Designed hairpin peptides interfere with amyloidogenesis pathways: fibril formation and cytotoxicity inhibition, interception of the preamyloid state. 2011 Sep 27 1
47 21905118 Inhibition of α-synuclein aggregation by small heat shock proteins. 2011 Oct 1
48 21986202 Neuroprotective and nootropic drug noopept rescues α-synuclein amyloid cytotoxicity. 2011 Dec 16 1
49 20132485 A novel, high-efficiency cellular model of fibrillar alpha-synuclein inclusions and the examination of mutations that inhibit amyloid formation. 2010 Apr 1
50 20140223 Ribosylation rapidly induces alpha-synuclein to form highly cytotoxic molten globules of advanced glycation end products. 2010 Feb 4 2