Hydrogen Peroxide

synuclein alpha ; Homo sapiens







53 Article(s)
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1 33809978 Oxidative Stress Conditions Result in Trapping of PHF-Core Tau (297-391) Intermediates. 2021 Mar 22 1
2 31735335 Upregulated PTPN2 induced by inflammatory response or oxidative stress stimulates the progression of thyroid cancer. 2020 Jan 29 1
3 32905883 α-Synuclein amplifies cytoplasmic peroxide flux and oxidative stress provoked by mitochondrial inhibitors in CNS dopaminergic neurons in vivo. 2020 Oct 1
4 29470695 A banana NAC transcription factor (MusaSNAC1) impart drought tolerance by modulating stomatal closure and H2O2 content. 2018 Mar 3
5 29689296 Early events in copper-ion catalyzed oxidation of α-synuclein. 2018 Jun 3
6 29922854 fMLP-dependent activation of Akt and ERK1/2 through ROS/Rho A pathways is mediated through restricted activation of the FPRL1 (FPR2) receptor. 2018 Aug 1
7 30249394 Exploring the role of methionine residues on the oligomerization and neurotoxic properties of DOPAL-modified α-synuclein. 2018 Oct 20 1
8 28159635 α-Synuclein binds to cytoplasmic vesicles in U251 glioblastoma cells. 2017 Mar 6 1
9 28163159 Mitochondrial ferritin protects SH-SY5Y cells against H2O2-induced oxidative stress and modulates α-synuclein expression. 2017 May 3
10 28164279 Calcipotriol inhibits α-synuclein aggregation in SH-SY5Y neuroblastoma cells by a Calbindin-D28k-dependent mechanism. 2017 Apr 1
11 29039448 Astragaloside IV attenuates the H2O2-induced apoptosis of neuronal cells by inhibiting α-synuclein expression via the p38 MAPK pathway. 2017 Dec 1
12 26940028 Excessive Iron and α-Synuclein Oligomer in Brain are Relevant to Pure Apathy in Parkinson Disease. 2016 Jul 1
13 25825709 α-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylation. 2015 Apr 14 2
14 24784227 UV-induced selective oxidation of Met5 to Met-sulfoxide leads to the formation of neurotoxic fibril-incompetent α-synuclein oligomers. 2014 Sep 1
15 23159813 Raised calcium and oxidative stress cooperatively promote alpha-synuclein aggregate formation. 2013 Apr 2
16 23353026 Oxidative stress involvement in manganese-induced alpha-synuclein oligomerization in organotypic brain slice cultures. 2013 Mar 8 1
17 22538490 Modeling Parkinson's disease using induced pluripotent stem cells. 2012 Jun 1
18 23047606 Hereditary ovarian cancer and two-compartment tumor metabolism: epithelial loss of BRCA1 induces hydrogen peroxide production, driving oxidative stress and NFκB activation in the tumor stroma. 2012 Nov 15 1
19 21336954 α-Synuclein increases U251 cells vulnerability to hydrogen peroxide by disrupting calcium homeostasis. 2011 Aug 3
20 21658409 Neuroprotection of α-synuclein under acute and chronic rotenone and maneb treatment is abolished by its familial Parkinson's disease mutations A30P, A53T and E46K. 2011 Dec 1
21 21710541 Lithium protects against oxidative stress-mediated cell death in α-synuclein-overexpressing in vitro and in vivo models of Parkinson's disease. 2011 Oct 1
22 20026206 Methionine oxidation stabilizes non-toxic oligomers of alpha-synuclein through strengthening the auto-inhibitory intra-molecular long-range interactions. 2010 Mar 1
23 18853169 Cellular glutathione peroxidase in human brain: cellular distribution, and its potential role in the degradation of Lewy bodies in Parkinson's disease and dementia with Lewy bodies. 2009 Jan 1
24 19263279 Glutathione synthesis against oxidant injury by peroxides in two alveolar epithelial cell lines. 2009 Mar 4
25 19328209 At low concentrations, 3,4-dihydroxyphenylacetic acid (DOPAC) binds non-covalently to alpha-synuclein and prevents its fibrillation. 2009 May 8 1
26 18239841 Products of Cu(II)-catalyzed oxidation of alpha-synuclein fragments containing M1-D2 and H50 residues in the presence of hydrogen peroxide. 2008 Feb 14 1
27 18986521 Anti-oxidant inhibition of hyaluronan fragment-induced inflammatory gene expression. 2008 Nov 5 1
28 16753318 Increased hydrogen peroxide concentration in the exhaled breath condensate of stable COPD patients after nebulized N-acetylcysteine. 2007 1
29 16978743 Parkinson's disease genetic mutations increase cell susceptibility to stress: mutant alpha-synuclein enhances H2O2- and Sin-1-induced cell death. 2007 Nov 2
30 17337120 Alpha-synuclein overexpression reduces gap junctional intercellular communication in dopaminergic neuroblastoma cells. 2007 Apr 18 1
31 17760417 A macrophage-nanozyme delivery system for Parkinson's disease. 2007 Sep-Oct 1
32 16778450 Inhibition of proliferation of endometrial stromal cells by trichostatin A, RU486, CDB-2914, N-acetylcysteine, and ICI 182780. 2006 1
33 16839607 Products of Cu(II)-catalyzed oxidation of the N-terminal fragments of alpha-synuclein in the presence of hydrogen peroxide. 2006 Oct 3
34 16984000 A spectroscopic study of some of the peptidyl radicals formed following hydroxyl radical attack on beta-amyloid and alpha-synuclein. 2006 Jul 1
35 15680224 Methionine oxidation, alpha-synuclein and Parkinson's disease. 2005 Jan 17 1
36 14640973 Bicarbonate enhances alpha-synuclein oligomerization and nitration: intermediacy of carbonate radical anion and nitrogen dioxide radical. 2004 Mar 1 1
37 14742448 Alpha-synuclein up-regulation and aggregation during MPP+-induced apoptosis in neuroblastoma cells: intermediacy of transferrin receptor iron and hydrogen peroxide. 2004 Apr 9 1
38 15079871 Overexpression of alpha-synuclein decreased viability and enhanced sensitivity to prostaglandin E(2), hydrogen peroxide, and a nitric oxide donor in differentiated neuroblastoma cells. 2004 May 1 2
39 12603836 Lipid interaction of alpha-synuclein during the metal-catalyzed oxidation in the presence of Cu2+ and H2O2. 2003 Mar 2
40 12661766 Enhanced oligomerization of the alpha-synuclein mutant by the Cu,Zn-superoxide dismutase and hydrogen peroxide system. 2003 Feb 28 2
41 12807439 Alpha-synuclein protects naive but not dbcAMP-treated dopaminergic cell types from 1-methyl-4-phenylpyridinium toxicity. 2003 Jul 1
42 11790792 alpha-Synuclein protects against oxidative stress via inactivation of the c-Jun N-terminal kinase stress-signaling pathway in neuronal cells. 2002 Mar 29 1
43 11958955 Aggregation of alpha-synuclein induced by the Cu,Zn-superoxide dismutase and hydrogen peroxide system. 2002 Mar 15 1
44 12031892 Formation of hydrogen peroxide and hydroxyl radicals from A(beta) and alpha-synuclein as a possible mechanism of cell death in Alzheimer's disease and Parkinson's disease. 2002 Jun 1 2
45 12453634 The ceruloplasmin and hydrogen peroxide system induces alpha-synuclein aggregation in vitro. 2002 Jul 2
46 11168363 Self-oligomerization and protein aggregation of alpha-synuclein in the presence of Coomassie Brilliant Blue. 2001 Jan 1
47 11301060 Release and aggregation of cytochrome c and alpha-synuclein are inhibited by the antiparkinsonian drugs, talipexole and pramipexole. 2001 Apr 6 1
48 11369507 alpha-Synuclein implicated in Parkinson's disease catalyses the formation of hydrogen peroxide in vitro. 2001 May 15 2
49 10799759 Enhanced vulnerability to oxidative stress by alpha-synuclein mutations and C-terminal truncation. 2000 1
50 10860544 Metal-catalyzed oxidation of alpha-synuclein in the presence of Copper(II) and hydrogen peroxide. 2000 Jun 15 3