Epinephrine

adrenoceptor alpha 2A ; Homo sapiens







19 Article(s)
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1 35245122 Structural insights into ligand recognition, activation, and signaling of the α2A adrenergic receptor. 2022 Mar 4 2
2 24723553 α2A-Adrenergic receptor polymorphism potentiates platelet reactivity in patients with stable coronary artery disease carrying the cytochrome P450 2C19*2 genetic variant. 2014 Jun 2
3 16854373 Identification of ADRA2A polymorphisms related to shear-mediated platelet function. 2006 Sep 8 2
4 12642394 Desensitization of alpha 2A-adrenoceptor signalling by modest levels of adrenaline is facilitated by beta 2-adrenoceptor-dependent GRK3 up-regulation. 2003 Mar 1
5 12649300 Dissimilar pharmacological responses by a new series of imidazoline derivatives at precoupled and ligand-activated alpha 2A-adrenoceptor states: evidence for effector pathway-dependent differential antagonism. 2003 Jun 1
6 11306720 Molecular mechanism for agonist-promoted alpha(2A)-adrenoceptor activation by norepinephrine and epinephrine. 2001 May 1
7 11520900 Differential capacities of the RGS1, RGS16 and RGS-GAIP regulators of G protein signaling to enhance alpha2A-adrenoreceptor agonist-stimulated GTPase activity of G(o1)alpha. 2001 Aug 1
8 10640303 Facilitation of constitutive alpha(2A)-adrenoceptor activity by both single amino acid mutation (Thr(373)Lys) and g(alphao) protein coexpression: evidence for inverse agonism. 2000 Feb 1
9 10622745 An Asp79Asn mutation of the alpha2A-adrenoceptor interferes equally with agonist activation of individual Gialpha-family G protein subtypes. 1999 Dec 3 1
10 9645466 Quantitative analysis of a cysteine351glycine mutation in the G protein Gi1alpha: effect on alpha2A-adrenoceptor-Gi1alpha fusion protein activation. 1998 May 22 1
11 9843377 Agonist-mediated downregulation of G alpha i via the alpha 2-adrenergic receptor is targeted by receptor-Gi interaction and is independent of receptor signaling and regulation. 1998 Nov 10 1
12 9313925 Selective inhibition of adenylyl cyclase by octopamine via a human cloned alpha 2A-adrenoceptor. 1997 Sep 1
13 7530955 Alpha 2A-adrenoceptors mediate activation of non-selective cation channels via Gi-proteins in human erythroleukaemia (HEL) cells. No evidence for a functional role of imidazoline receptors in modulating calcium. 1995 Jan 18 1
14 7908287 Differential desensitization and phosphorylation of three cloned and transfected alpha 2-adrenergic receptor subtypes. 1994 Apr 1 2
15 7910371 Contribution of ligand structure to activation of alpha 2-adrenergic receptor subtype coupling to Gs. 1994 Apr 1
16 8075868 Rapid desensitization of adrenaline- and neuropeptide Y-stimulated Ca2+ mobilization in HEL-cells. 1994 Jun 1
17 7903535 Pharmacological characterization of epinephrine-stimulated GTPase activity in human platelet membranes. 1993 Dec 3 1
18 1311318 Sites in the third intracellular loop of the alpha 2A-adrenergic receptor confer short term agonist-promoted desensitization. Evidence for a receptor kinase-mediated mechanism. 1992 Mar 5 1
19 1334095 Subtype-selective desensitization of alpha 2-adrenergic receptors. Different mechanisms control short and long term agonist-promoted desensitization of alpha 2C10, alpha 2C4, and alpha 2C2. 1992 Dec 15 1