malic acid

fumarate hydratase ; Homo sapiens







31 Article(s)
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1 33848143 Computational Saturation Screen Reveals the Landscape of Mutations in Human Fumarate Hydratase. 2021 Apr 26 1
2 31522598 Identification of Activators of Human Fumarate Hydratase by Quantitative High-Throughput Screening. 2020 Jan 2
3 31123043 Tolerance of DNA Replication Stress Is Promoted by Fumarate Through Modulation of Histone Demethylation and Enhancement of Replicative Intermediate Processing in Saccharomyces cerevisiae. 2019 Jul 1
4 29130499 Combined metabolomic and correlation networks analyses reveal fumarase insufficiency altered amino acid metabolism. 2018 Apr 1
5 29302811 Gene expression analysis in peripheral blood cells of patients with hereditary leiomyomatosis and renal cell cancer syndrome (HLRCC): identification of NRF2 pathway activation. 2018 Oct 1
6 28104508 Exposure to high levels of fumarate and succinate leads to apoptotic cytotoxicity and altered global DNA methylation profiles in vitro. 2017 Apr 2
7 28538181 Malate and Aspartate Increase L-Arginine and Nitric Oxide and Attenuate Hypertension. 2017 May 23 1
8 29226743 Molecular docking and molecular dynamics simulations of fumarate hydratase and its mutant H235N complexed with pyromellitic acid and citrate. 2017 Dec 1
9 31223144 The long non-coding RNA H19 - a new player in hepatocellular carcinoma. 2017 Oct 1 1
10 31225435 Fumarase mediates transcriptional response to nutrient stress. 2017 Oct 1 1
11 26380143 Abnormal Cystic Tumor in a Patient with Hereditary Leiomyomatosis and Renal Cell Cancer Syndrome: Evidence of a Precursor Lesion? 2015 1
12 23886887 A spectrophotometric coupled enzyme assay to measure the activity of succinate dehydrogenase. 2013 Nov 1 2
13 21498518 Identification of the catalytic mechanism and estimation of kinetic parameters for fumarase. 2011 Jun 17 1
14 21849978 Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase. 2011 Aug 17 2
15 17211469 HIF and fumarate hydratase in renal cancer. 2007 Feb 12 2
16 15663510 Familial multiple cutaneous and uterine leiomyomas associated with papillary renal cell cancer. 2005 Jan 1
17 16154636 Blue native polyacrylamide gel electrophoresis and the monitoring of malate- and oxaloacetate-producing enzymes. 2005 Sep 30 2
18 20641983 Hyperpolarized [1,4-13C2]fumarate as an imaging agent of tumor cell death in vivo 2004 2
19 14643060 On the association of succinate dehydrogenase mutations with hereditary paraganglioma. 2003 Dec 1
20 11797209 [Study on the optimal conditions in simultaneous reaction and separation for L-malic acid production]. 2001 Sep 1
21 8357797 Role of conformational change in the fumarase reaction cycle. 1993 Aug 24 1
22 3332992 Enzyme-enzyme interactions as modulators of the metabolic flux through the citric acid cycle. 1987 1
23 6626216 Absolute configuration of a chiral CHD group via neutron diffraction: confirmation of the absolute stereochemistry of the enzymatic formation of malic acid. 1983 Sep 30 1
24 6800407 Induction of fumarase in resting Euglena. 1982 Feb 25 1
25 7333283 Stereochemical investigation of the phosphoketolase reaction. The formation of chiral [2H1,3H]acetyl phosphate. 1981 Dec 1
26 24306375 Nutritional regulation of organelle biogenesis inEuglena: Photo- and metabolite induction of mitochondria. 1980 Jan 1
27 962872 Deviation from Michaelis-Menten kinetics for fumarase. 1976 Aug 1 1
28 163157 Serum and erythocyte argininosuccinate lyase assay by NADH fluorescence generated from formed fumarate. 1975 Feb 1
29 238846 Substrate stereochemistry of the acetyl-CoA acetyltransferase reaction. 1975 May 1
30 1156576 Stereochemistry of propionyl-coenzyme A and pyruvate carboxylations catalyzed by transcarboxylase. 1975 Jul 1
31 5811774 Secondary isotope effects in the dehydration of malic acid by fumarate hydratase. 1969 Oct 8 1