Serine

interferon alpha 1 ; Homo sapiens







49 Article(s)
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1 34131022 The transmembrane serine protease hepsin suppresses type I interferon induction by cleaving STING. 2021 Jun 15 1
2 30439382 PASylated interferon α efficiently suppresses hepatitis B virus and induces anti-HBs seroconversion in HBV-transgenic mice. 2019 Jan 1
3 27802159 Phosphorylation of STAT2 on serine-734 negatively regulates the IFN-α-induced antiviral response. 2016 Nov 15 1
4 26359551 Antiviral role of grouper STING against iridovirus infection. 2015 Nov 1
5 24449862 Novel antiviral host factor, TNK1, regulates IFN signaling through serine phosphorylation of STAT1. 2014 Feb 4 1
6 22996189 Hepatitis B virus polymerase impairs interferon-α-induced STA T activation through inhibition of importin-α5 and protein kinase C-δ. 2013 Feb 1
7 22550181 Regulatory effects of mTORC2 complexes in type I IFN signaling and in the generation of IFN responses. 2012 May 15 2
8 21478011 Type I interferons as radiosensitisers for pancreatic cancer. 2011 Sep 1
9 21865166 Tyrosine phosphorylation of protein kinase D2 mediates ligand-inducible elimination of the Type 1 interferon receptor. 2011 Oct 14 1
10 22065572 Inhibitor of κB kinase epsilon (IKK(epsilon)), STAT1, and IFIT2 proteins define novel innate immune effector pathway against West Nile virus infection. 2011 Dec 30 3
11 20406818 Negative role of RIG-I serine 8 phosphorylation in the regulation of interferon-beta production. 2010 Jun 25 1
12 19014879 Interferon alpha increases metalloproteinase-13 gene expression through a polyomavirus enhancer activator 3-dependent pathway in hepatic stellate cells. 2009 Jan 1
13 19396596 Bortezomib pre-treatment prolongs interferon-alpha-induced STAT1 phosphorylation in melanoma cells. 2009 Dec 1
14 18417573 Henipavirus V protein association with Polo-like kinase reveals functional overlap with STAT1 binding and interferon evasion. 2008 Jul 4
15 18722370 Cigarette smoking products suppress anti-viral effects of Type I interferon via phosphorylation-dependent downregulation of its receptor. 2008 Sep 22 2
16 17332776 C-Raf antagonizes apoptosis induced by IFN-alpha in human lung cancer cells by phosphorylation and increase of the intracellular content of elongation factor 1A. 2007 May 1
17 17554018 Epstein-Barr virus induces a distinct form of DNA-bound STAT1 compared with that found in interferon-stimulated B lymphocytes. 2007 Jul 1
18 16751416 Antitumor activity of IFN-lambda in murine tumor models. 2006 Jun 15 1
19 15850832 Role of protein kinase C-delta (PKC-delta) in the generation of the effects of IFN-alpha in chronic myelogenous leukemia cells. 2005 May 4
20 16260419 Interferon-alpha-induced expression of phospholipid scramblase 1 through STAT1 requires the sequential activation of protein kinase Cdelta and JNK. 2005 Dec 30 1
21 12759354 Activation of the p70 S6 kinase and phosphorylation of the 4E-BP1 repressor of mRNA translation by type I interferons. 2003 Jul 25 1
22 12792788 Synergistic growth inhibitory effects of interferon-alpha and lovastatin on bcr-abl positive leukemic cells. 2003 Jul 1
23 12883649 Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation. 2003 Sep 1
24 11846979 Enhancement and diversification of IFN induction by IRF-7-mediated positive feedback. 2002 Jan 1
25 12051728 Involvement of IL-1beta and IL-10 in IFN-alpha-mediated antiviral gene induction in human hepatoma cells. 2002 Jun 7 1
26 12161037 Low expression of interferon-stimulated genes in active multiple sclerosis is linked to subnormal phosphorylation of STAT1. 2002 Aug 1
27 11162588 Frap-dependent serine phosphorylation of IRS-1 inhibits IRS-1 tyrosine phosphorylation. 2001 Jan 26 3
28 11277596 Analgesic domains of interferon-alpha. 2001 Mar 26 2
29 10777558 Distinct mechanisms of STAT phosphorylation via the interferon-alpha/beta receptor. Selective inhibition of STAT3 and STAT5 by piceatannol. 2000 Apr 28 2
30 10900338 Distinct domains of IFNalpha mediate immune and analgesic effects respectively. 2000 Aug 1 2
31 11095741 IFNalpha/beta promotes cell survival by activating NF-kappa B. 2000 Dec 5 1
32 11956564 [Distinct structural bases of the immunoregulatory and central analgesic effects of IFNalpha]. 2000 Jun 1
33 10488146 JAK1-dependent phosphorylation of insulin receptor substrate-1 (IRS-1) is inhibited by IRS-1 serine phosphorylation. 1999 Sep 24 2
34 9707562 Primary activation of interferon A and interferon B gene transcription by interferon regulatory factor 3. 1998 Aug 18 3
35 9822609 Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7. 1998 Nov 16 2
36 9036989 Activation of the phosphatidylinositol 3-kinase serine kinase by IFN-alpha. 1997 Mar 1 3
37 8943379 Activation of STAT4 by IL-12 and IFN-alpha: evidence for the involvement of ligand-induced tyrosine and serine phosphorylation. 1996 Dec 1 3
38 7535054 Dual modulation of phosphorylation of a 60 kDa nuclear protein in interferon-alpha treated Daudi cells. 1995 Mar 17 1
39 7508909 Interferon alpha induces rapid tyrosine phosphorylation of the vav proto-oncogene product in hematopoietic cells. 1994 Feb 4 1
40 8279808 Anti-rhinoviral activity of recombinant and hybrid species of interferon alpha. 1993 Oct 2
41 1385434 Interferon alpha induces rapid tyrosine phosphorylation of the alpha subunit of its receptor. 1992 Nov 25 1
42 2332772 Phase II trial of interferon-beta-serine in metastatic renal cell carcinoma. 1990 May 8
43 2826671 Structure-function analysis of mouse interferon alpha species: MuIFN-alpha 10, a subspecies with low antiviral activity. 1988 Jan 1
44 3045221 Clinical and biological effects of recombinant interferon-beta administered intravenously daily in phase I trial. 1988 Jun 2
45 2416427 Synergistic antiproliferative effects of human recombinant alpha 54- or beta ser-interferon with gamma-interferon on human cell lines of various histogenesis. 1986 Feb 1
46 3014018 Interferon-beta ser as prophylaxis against experimental rhinovirus infection in volunteers. 1986 Apr 1
47 3572088 Antiviral and antiproliferative activities of interferon-alpha 1: the role of cysteine residues. 1986 Dec 2
48 3756886 Phase I/II trial of human recombinant beta-interferon serine in patients with renal cell carcinoma. 1986 Oct 3
49 3160832 Recombinant DNA-derived interferons-alpha and -beta modulate the alloactivated proliferative response of bulk and cloned human lymphocytes. 1985 Jun 1