Tyrosine

interferon alpha 1 ; Homo sapiens







150 Article(s)
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101 9769120 Unresponsiveness to interferon associated with STAT1 protein deficiency in a gastric adenocarcinoma cell line. 1998 Oct 1
102 9804758 Role of the STAT1-SH2 domain and STAT2 in the activation and nuclear translocation of STAT1. 1998 Nov 13 1
103 9020188 Stat2 is a transcriptional activator that requires sequence-specific contacts provided by stat1 and p48 for stable interaction with DNA. 1997 Feb 14 2
104 9038355 The vav proto-oncogene product (p95vav) interacts with the Tyk-2 protein tyrosine kinase. 1997 Feb 10 2
105 9121453 Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling. 1997 Apr 1
106 9218843 Rescue by cytokines of apoptotic cell death induced by IL-2 deprivation of human antigen-specific T cell clones. 1997 Jul 1
107 9242679 Distinct STAT structure promotes interaction of STAT2 with the p48 subunit of the interferon-alpha-stimulated transcription factor ISGF3. 1997 Aug 8 1
108 9249040 Kinase-deficient forms of Jak1 and Tyk2 inhibit interferon alpha signaling in a dominant manner. 1997 Jul 1 2
109 9374471 The type I interferon receptor mediates tyrosine phosphorylation of the CrkL adaptor protein. 1997 Nov 28 1
110 8524306 Function of Stat2 protein in transcriptional activation by alpha interferon. 1996 Jan 3
111 8550573 The type I interferon receptor mediates tyrosine phosphorylation of insulin receptor substrate 2. 1996 Jan 5 2
112 8605876 Phosphorylated interferon-alpha receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113 kDa STAT2 protein. 1996 Mar 1 2
113 8626489 Direct association of STAT3 with the IFNAR-1 chain of the human type I interferon receptor. 1996 Apr 5 2
114 8628273 Molecular characterization of an alpha interferon receptor 1 subunit (IFNaR1) domain required for TYK2 binding and signal transduction. 1996 May 2
115 8650265 The IRS-signalling system in insulin and cytokine action. 1996 Feb 29 1
116 8657115 Inhibition of alpha interferon but not gamma interferon signal transduction by phorbol esters is mediated by a tyrosine phosphatase. 1996 Apr 3
117 8780698 Interaction of the c-cbl proto-oncogene product with the Tyk-2 protein tyrosine kinase. 1996 Aug 23 1
118 8780896 Constitutive STAT1 tyrosine phosphorylation in U937 monocytes overexpressing the TYK2 protein tyrosine kinase does not induce gene transcription. 1996 Jun 9
119 8910507 A negative regulatory region in the intracellular domain of the human interferon-alpha receptor. 1996 Nov 8 2
120 8917387 Mechanism of interferon action: in vivo activation of 91 kDa transcription factor. 1996 Sep-Oct 1
121 8943349 Activation of different Stat5 isoforms contributes to cell-type-restricted signaling in response to interferons. 1996 Dec 1
122 8943379 Activation of STAT4 by IL-12 and IFN-alpha: evidence for the involvement of ligand-induced tyrosine and serine phosphorylation. 1996 Dec 1 2
123 8969169 The human type I interferon receptor. Identification of the interferon beta-specific receptor-associated phosphoprotein. 1996 Dec 27 1
124 7479825 Expression and signaling specificity of the IFNAR chain of the type I interferon receptor complex. 1995 Nov 7 4
125 7532663 Resistance of melanoma cell lines to interferons correlates with reduction of IFN-induced tyrosine phosphorylation. Induction of the anti-viral state by IFN is prevented by tyrosine kinase inhibitors. 1995 Mar 1 7
126 7535054 Dual modulation of phosphorylation of a 60 kDa nuclear protein in interferon-alpha treated Daudi cells. 1995 Mar 17 1
127 7535819 The Fc gamma RI receptor signals through the activation of hck and MAP kinase. 1995 Apr 15 1
128 7559568 Interaction of the transcriptional activator Stat-2 with the type I interferon receptor. 1995 Oct 20 1
129 7608146 Interferon-alpha engages the insulin receptor substrate-1 to associate with the phosphatidylinositol 3'-kinase. 1995 Jul 7 3
130 7629131 Association of the interferon-dependent tyrosine kinase Tyk-2 with the hematopoietic cell phosphatase. 1995 Aug 4 1
131 7729946 alpha-Interferon potentiates epidermal growth factor receptor-mediated effects on human epidermoid carcinoma KB cells. 1995 May 4 2
132 7759950 Soluble and membrane-anchored forms of the human IFN-alpha/beta receptor. 1995 May 1
133 7884896 Tyrosine phosphorylation of measles virus nucleocapsid protein in persistently infected neuroblastoma cells. 1995 Apr 1
134 21552922 The expression of stat91, ras-independent signal transducer and activator, in human gastric carcinomas. 1995 Oct 2
135 7508909 Interferon alpha induces rapid tyrosine phosphorylation of the vav proto-oncogene product in hematopoietic cells. 1994 Feb 4 4
136 7510216 Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions. 1994 Mar 11 1
137 7929242 Cell cycle-dependent modulation of alpha-interferon-inducible gene expression and activation of signaling components in Daudi cells. 1994 Oct 14 1
138 7988557 Activation of JAK kinases and STAT proteins by interleukin-2 and interferon alpha, but not the T cell antigen receptor, in human T lymphocytes. 1994 Dec 1 1
139 8027027 Tyrosine phosphorylation of the alpha and beta subunits of the type I interferon receptor. Interferon-beta selectively induces tyrosine phosphorylation of an alpha subunit-associated protein. 1994 Jul 8 5
140 8055912 Activation of the protein tyrosine kinase tyk2 by interferon alpha/beta. 1994 Jul 15 1
141 8114747 Mutant cell lines unresponsive to alpha/beta and gamma interferon are defective in tyrosine phosphorylation of ISGF-3 alpha components. 1994 Mar 2
142 8306959 Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF-1 promoter to mediate induction by IFN alpha and IFN gamma, and is likely to autoregulate the p91 gene. 1994 Jan 1 2
143 7504784 Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins. 1993 Dec 9 1
144 7504785 Interferon-induced nuclear signalling by Jak protein tyrosine kinases. 1993 Dec 9 1
145 8321205 In vitro activation of a transcription factor by gamma interferon requires a membrane-associated tyrosine kinase and is mimicked by vanadate. 1993 Jul 1
146 8378773 Tyrosine phosphorylation of DNA binding proteins by multiple cytokines. 1993 Sep 24 1
147 1385434 Interferon alpha induces rapid tyrosine phosphorylation of the alpha subunit of its receptor. 1992 Nov 25 6
148 1496401 Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. 1992 Aug 7 2
149 1995306 Alpha-interferon reduces in vivo phosphorylation of P210bcr/abl protein during hemin-induced erythroid differentiation of K-562 cells. 1991 Mar 1
150 2526185 Structure-function studies of interferons-alpha: amino acid substitutions at the conserved residue tyrosine 123 in human interferon-alpha 1. 1989 Jun 2