Guanine Nucleotides

H3 histone pseudogene 16 ; Homo sapiens







46 Article(s)
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1 16283548 Specificity of inhibition of ras-p21 signal transduction by peptides from GTPase activating protein (GAP) and the son-of sevenless (SOS) ras-specific guanine nucleotide exchange protein. 2005 May 1
2 16323045 Comparison of the predicted structures of loops in the ras-SOS protein bound to a single ras-p21 protein with the crystallographically determined structures in SOS bound to two ras-p21 proteins. 2005 Aug 2
3 15200053 Comparison of molecular dynamics averaged structures for complexes of normal and oncogenic ras-p21 with SOS nucleotide exchange protein, containing computed conformations for three crystallographically undefined domains, suggests a potential role of these domains in ras signaling. 2004 Apr 1
4 15200054 Loop domain peptides from the SOS ras-guanine nucleotide exchange protein, identified from molecular dynamics calculations, strongly inhibit ras signaling. 2004 Apr 2
5 12740440 Structural and biochemical studies of p21Ras S-nitrosylation and nitric oxide-mediated guanine nucleotide exchange. 2003 May 27 1
6 10661494 Aberrant expression of nNOS in pyramidal neurons in Alzheimer's disease is highly co-localized with p21ras and p16INK4a. 2000 Jan 3 1
7 10087060 The mitogen-activated protein kinase pathway mediates estrogen neuroprotection after glutamate toxicity in primary cortical neurons. 1999 Apr 1 1
8 10839623 Molecular dynamics analysis of the structures of ras-guanine nucleotide exchange protein (SOS) bound to wild-type and oncogenic ras-p21. Identification of effector domains of SOS. 1999 Nov 1
9 9020151 A molecular redox switch on p21(ras). Structural basis for the nitric oxide-p21(ras) interaction. 1997 Feb 14 2
10 9236898 Ras p21 protein immunoreactivity and its relationship to p53 expression and prognosis in gallbladder and extrahepatic biliary carcinoma. 1997 Jun 1
11 8631299 The heterotrimeric G q protein-coupled angiotensin II receptor activates p21 ras via the tyrosine kinase-Shc-Grb2-Sos pathway in cardiac myocytes. 1996 Feb 15 1
12 8663295 Role of the Raf/mitogen-activated protein kinase pathway in p21ras desensitization. 1996 Jul 12 1
13 8810926 High frequency (139.5 GHz) electron paramagnetic resonance characterization of Mn(II)-H2(17)O interactions in GDP and GTP forms of p21 ras. 1996 Sep 17 2
14 8887687 Calcium-dependent immediate-early gene induction in lymphocytes is negatively regulated by p21Ha-ras. 1996 Nov 1
15 7673152 p21ras as a common signaling target of reactive free radicals and cellular redox stress. 1995 Sep 8 1
16 7706235 Nitric oxide-stimulated guanine nucleotide exchange on p21ras. 1995 Mar 31 1
17 7853016 Changing expression of GTPase activating proteins with differentiation in neuroblastoma. 1994 Nov 1
18 8114695 Involvement of Shc in insulin- and epidermal growth factor-induced activation of p21ras. 1994 Mar 1
19 8142894 Hydrogen bond interactions of G proteins with the guanine ring moiety of guanine nucleotides. 1994 Jan 1
20 15299413 Crystallization and preliminary X-ray structure analysis of thermally unstable p21(H-ras) guanosine complexes. 1994 Jul 1 1
21 8386636 Nucleotide binding and GTP hydrolysis by the 21-kDa product of the c-H-ras gene as monitored by proton-NMR spectroscopy. 1993 Apr 15 1
22 8419371 Kinetic and structural analysis of the Mg(2+)-binding site of the guanine nucleotide-binding protein p21H-ras. 1993 Jan 15 2
23 1351293 Studies on the structure and mechanism of H-ras p21. 1992 Apr 29 1
24 1351296 The kinetic mechanism of the GAP-activated GTPase of p21 ras. 1992 Apr 29 1
25 1429539 A model for the catalytic site of F1-ATPase based on analogies to nucleotide-binding domains of known structure. 1992 Oct 1
26 1533366 Studies on protein-DNA interactions using the resonant recognition model. Application to repressors and transforming proteins. 1992 Apr 15 2
27 1740128 Effects of ions on the intrinsic activities of c-H-ras protein p21. A comparison with elongation factor Tu. 1992 Feb 15 1
28 1932015 An isotope edited classical Raman difference spectroscopic study of the interactions of guanine nucleotides with elongation factor Tu and H-ras p21. 1991 Nov 12 2
29 2180382 No evidence for the mutation of ras gene in psoriatic epidermis. 1990 1
30 2199064 Three-dimensional structures of H-ras p21 mutants: molecular basis for their inability to function as signal switch molecules. 1990 Aug 10 1
31 2476675 Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation. 1989 Sep 21 2
32 2668035 Conformational changes occurring in N-ras p21 in response to binding of guanine nucleotide and metal ions probed by proteolysis performed under controlled conditions. 1989 Aug 14 2
33 3140742 Enhanced expression of ras gene products in psoriatic epidermis. 1988 1
34 2439901 Neutralizing monoclonal antibody against ras oncogene product p21 which impairs guanine nucleotide exchange. 1987 May 1
35 3328019 Critical amino acids of p21 protein are located within beta-turns: further evaluation. 1987 Oct 7 1
36 3554231 Properties of a genetically engineered G domain of elongation factor Tu. 1987 May 1
37 3012529 Reduced hormone-stimulated adenylate cyclase activity in NIH-3T3 cells expressing the EJ human bladder ras oncogene. 1986 Jun 2
38 3321304 Genetic and biochemical analysis of ras p21 structure. 1986 7
39 3333361 Structure and function of p21 ras proteins. 1986 1
40 3537694 Biochemical characterization of polypeptides encoded by mutated human Ha-ras1 genes. 1986 Feb 1
41 3540608 Activation of ras p21 transforming properties associated with an increase in the release rate of bound guanine nucleotide. 1986 Dec 1
42 3898366 A model for the tertiary structure of p21, the product of the ras oncogene. 1985 Oct 4 1
43 3915772 Antibody of predetermined specificity to a carboxy-terminal region of H-ras gene products inhibits their guanine nucleotide-binding function. 1985 Nov 3
44 6147754 Comparative biochemical properties of normal and activated human ras p21 protein. 1984 Aug 23-29 1
45 6392849 Expression and characterization of ras mRNAs from Saccharomyces cerevisiae. 1984 Nov 1
46 6610834 Epidermal growth factor stimulates guanine nucleotide binding activity and phosphorylation of ras oncogene proteins. 1984 Jul 12-18 1