Reactive Oxygen Species

H3 histone pseudogene 16 ; Homo sapiens







37 Article(s)
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1 35085581 Piperlongumine induces ROS mediated apoptosis by transcriptional regulation of SMAD4/P21/P53 genes and synergizes with doxorubicin in osteosarcoma cells. 2022 Feb 25 1
2 35111249 Revisiting therapeutic strategies for ovarian cancer by focusing on redox homeostasis. 2022 Mar 1
3 34367464 Advanced Oxidation Protein Products Induce G1/G0-Phase Arrest in Ovarian Granulosa Cells via the ROS-JNK/p38 MAPK-p21 Pathway in Premature Ovarian Insufficiency. 2021 1
4 31995555 Application of non-invasive low-intensity pulsed electric field with thermal cycling-hyperthermia for synergistically enhanced anticancer effect of chlorogenic acid on PANC-1 cells. 2020 1
5 32294550 Delivery of MutT homolog 1 inhibitor by functionalized graphene oxide nanoparticles for enhanced chemo-photodynamic therapy triggers cell death in osteosarcoma. 2020 Jun 1
6 31404677 Photoirradiation after aminolevulinic acid treatment suppresses cancer cell proliferation through the HO-1/p21 pathway. 2019 Dec 3
7 31462222 Ethanol extract of asiasari radix preferentially induces apoptosis in G361 human melanoma cells by differential regulation of p53. 2019 Aug 28 2
8 27238838 Foxp3 is a key downstream regulator of p53-mediated cellular senescence. 2017 Jan 12 4
9 28081982 Umbilical cord-derived mesenchymal stromal cell-conditioned medium exerts in vitro antiaging effects in human fibroblasts. 2017 Mar 2
10 28661480 Role of peroxiredoxin2 downregulation in recurrent miscarriage through regulation of trophoblast proliferation and apoptosis. 2017 Jun 29 1
11 28691365 Cooperation between p21 and Akt is required for p53-dependent cellular senescence. 2017 Oct 1
12 29051574 Florfenicol-induced Mitochondrial Dysfunction Suppresses Cell Proliferation and Autophagy in Fibroblasts. 2017 Oct 19 2
13 26934645 Proteasomal degradation of sphingosine kinase 1 and inhibition of dihydroceramide desaturase by the sphingosine kinase inhibitors, SKi or ABC294640, induces growth arrest in androgen-independent LNCaP-AI prostate cancer cells. 2016 Mar 29 1
14 27233942 Designing piperlongumine-directed anticancer agents by an electrophilicity-based prooxidant strategy: A mechanistic investigation. 2016 Aug 1
15 25304329 Increased effectiveness of carbon ions in the production of reactive oxygen species in normal human fibroblasts. 2015 Jan 1
16 26162681 Potent organo-osmium compound shifts metabolism in epithelial ovarian cancer cells. 2015 Jul 21 2
17 24930072 Synthesis and anti-tumor activity evaluation of Matijin-Su derivatives. 2014 Oct 1
18 23124852 Wnt/β-catenin signaling induces the aging of mesenchymal stem cells through promoting the ROS production. 2013 Feb 1
19 23219618 CD34+ cells from patients with myelodysplastic syndrome present different p21 dependent premature senescence. 2013 Mar 1
20 23546866 Reactive oxygen species-mediated activation of the Akt/ASK1/p38 signaling cascade and p21(Cip1) downregulation are required for shikonin-induced apoptosis. 2013 Jul 3
21 24005866 Ziyuglycoside II inhibits the growth of human breast carcinoma MDA-MB-435 cells via cell cycle arrest and induction of apoptosis through the mitochondria dependent pathway. 2013 Sep 3 2
22 22112863 The HDAC inhibitor depsipeptide transactivates the p53/p21 pathway by inducing DNA damage. 2012 Feb 1 1
23 23085518 T63, a new 4-arylidene curcumin analogue, induces cell cycle arrest and apoptosis through activation of the reactive oxygen species-FOXO3a pathway in lung cancer cells. 2012 Dec 15 1
24 23257465 [Reactive oxygen species and bone marrow hematopoietic stem cell senescence]. 2012 Dec 1
25 21310484 7-b, a novel amonafide analogue, cause growth inhibition and apoptosis in Raji cells via a ROS-mediated mitochondrial pathway. 2011 May 1
26 21816217 Autophagy regulates ROS-induced cellular senescence via p21 in a p38 MAPKα dependent manner. 2011 Nov 1
27 21878644 Drug-induced senescence generates chemoresistant stemlike cells with low reactive oxygen species. 2011 Oct 28 2
28 19544329 Activation of p53/p21/PUMA alliance and disruption of PI-3/Akt in multimodal targeting of apoptotic signaling cascades in cervical cancer cells by a pentacyclic triterpenediol from Boswellia serrata. 2009 Dec 1
29 17477906 Cytoplasmic localization and ubiquitination of p21(Cip1) by reactive oxygen species. 2007 Jun 22 3
30 17595331 A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche. 2007 Oct 15 1
31 17626009 Chronic treatment with resveratrol induces redox stress- and ataxia telangiectasia-mutated (ATM)-dependent senescence in p53-positive cancer cells. 2007 Sep 14 1
32 14977888 Oxysterol mixtures prevent proapoptotic effects of 7-ketocholesterol in macrophages: implications for proatherogenic gene modulation. 2004 Apr 1
33 15059930 Phosphoinositide-dependent kinase 1 and p21-activated protein kinase mediate reactive oxygen species-dependent regulation of platelet-derived growth factor-induced smooth muscle cell migration. 2004 May 14 1
34 12726921 Role of reactive oxygen species and MAPKs in vanadate-induced G(2)/M phase arrest. 2003 May 15 1
35 11864927 Protection of human endothelial cells from oxidative stress: role of Ras-ERK1/2 signaling. 2002 Feb 26 1
36 9876011 Modulation of ras p21 oncoprotein levels and DNA strand breakage in human cells with chemotherapeutic agents and/or deferoxamine. 1998 1
37 9054359 Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts. 1997 Mar 14 1