NADP

RNA, U1 small nuclear 1 ; Homo sapiens







27 Article(s)
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Title
Pub. Year
#Total Relationships
1 29073307 A follow-up history of young man with apparent cortisone reductase deficiency (ACRD) - several years after diagnosis. 2017 1
2 24447464 Identification of novel 11β-HSD1 inhibitors by combined ligand- and structure-based virtual screening. 2014 Mar 25 1
3 21138273 Synthesis and biological evaluation of (6- and 7-phenyl) coumarin derivatives as selective nonsteroidal inhibitors of 17β-hydroxysteroid dehydrogenase type 1. 2011 Jan 13 1
4 21163329 Direct regulation of glucose and not insulin on hepatic hexose-6-phosphate dehydrogenase and 11β-hydroxysteroid dehydrogenase type 1. 2011 Feb 10 1
5 20826560 Contribution of fructose-6-phosphate to glucocorticoid activation in the endoplasmic reticulum: possible implication in the metabolic syndrome. 2010 Oct 1
6 18778749 11beta-Hydroxysteroid dehydrogenase 1 reductase activity is dependent on a high ratio of NADPH/NADP(+) and is stimulated by extracellular glucose. 2009 Mar 25 3
7 19010388 Hexose-6-phosphate dehydrogenase modulates the effect of inhibitors and alternative substrates of 11beta-hydroxysteroid dehydrogenase 1. 2009 Mar 25 1
8 19121282 H6PDH interacts directly with 11beta-HSD1: implications for determining the directionality of glucocorticoid catalysis. 2009 Mar 1 1
9 19416720 A novel NADP(+)-dependent dehydrogenase activity for 7alpha/beta- and 11beta-hydroxysteroids in human liver nuclei: A third 11beta-hydroxysteroid dehydrogenase. 2009 Jun 15 2
10 19429452 Selective inhibition of 17beta-hydroxysteroid dehydrogenase type 1 (17betaHSD1) reduces estrogen responsive cell growth of T47-D breast cancer cells. 2009 Apr 1
11 19824648 Synthesis and biological evaluation of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) inhibitors based on a thieno[2,3-d]pyrimidin-4(3H)-one core. 2009 Nov 12 1
12 18224704 A 3D QSAR model of 17beta-HSD1 inhibitors based on a thieno[2,3-d]pyrimidin-4(3H)-one core applying molecular dynamics simulations and ligand-protein docking. 2008 Mar 1
13 18336279 The role of 11beta-hydroxysteroid dehydrogenase in metabolic disease and therapeutic potential of 11beta-hsd1 inhibitors. 2008 1
14 17588937 11beta-Hydroxysteroid Dehydrogenase Type 1 Regulation by Intracellular Glucose 6-Phosphate Provides Evidence for a Novel Link between Glucose Metabolism and Hypothalamo-Pituitary-Adrenal Axis Function. 2007 Sep 14 1
15 17624766 7alpha- and 7beta-hydroxy-epiandrosterone as substrates and inhibitors for the human 11beta-hydroxysteroid dehydrogenase type 1. 2007 Jun-Jul 1
16 18209879 Adipose tissue expression of 11beta-hydroxysteroid dehydrogenase type 1 in Cushing's syndrome and in obesity. 2007 Nov 1
17 16356929 Hexose-6-phosphate dehydrogenase knock-out mice lack 11 beta-hydroxysteroid dehydrogenase type 1-mediated glucocorticoid generation. 2006 Mar 10 1
18 16892382 Focused libraries of 16-substituted estrone derivatives and modified e-ring steroids: inhibitors of 17beta-hydroxysteroid dehydrogenase type 1. 2006 Apr 1
19 17017977 Type 1 11beta-hydroxysteroid dehydrogenase as universal drug target in metabolic diseases? 2006 Sep 1
20 15774558 Minireview: hexose-6-phosphate dehydrogenase and redox control of 11{beta}-hydroxysteroid dehydrogenase type 1 activity. 2005 Jun 2
21 12604234 17-beta-Hydroxysteroid dehydrogenase type 1: computational design of active site inhibitors targeted to the Rossmann fold. 2003 Feb 1 1
22 11604236 Modulation of 11 beta-hydroxysteroid dehydrogenase type 2 activity in Ishikawa cells is associated with changes in cellular proliferation. 2001 Oct 25 1
23 9927655 Structure of the ternary complex of human 17beta-hydroxysteroid dehydrogenase type 1 with 3-hydroxyestra-1,3,5,7-tetraen-17-one (equilin) and NADP+. 1999 Feb 2 2
24 10385414 Differentiation of adipose stromal cells: the roles of glucocorticoids and 11beta-hydroxysteroid dehydrogenase. 1999 Jul 1
25 9525918 Unusual charge stabilization of NADP+ in 17beta-hydroxysteroid dehydrogenase. 1998 Apr 3 1
26 9120678 Human hypertension caused by mutations in the 11 beta-hydroxysteroid dehydrogenase gene: a molecular analysis of apparent mineralocorticoid excess. 1996 Dec 2
27 7588404 Cloning of the 11 beta HSD type II enzyme from human kidney. 1995 Feb-May 1