Thymidine

thymidine phosphorylase ; Homo sapiens







60 Article(s)
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1 35193822 Multifunctional role of thymidine phosphorylase in cancer. 2022 Jun 3
2 35341481 Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes. 2022 Mar 28 1
3 33533561 Hematopoietic stem cell transplantation for mitochondrial neurogastrointestinal encephalopathy: A single-center experience underscoring the multiple factors involved in the prognosis. 2021 May 2
4 34480004 STING-driven interferon signaling triggers metabolic alterations in pancreas cancer cells visualized by [18F]FLT PET imaging. 2021 Sep 7 2
5 32183169 Quantification of Plasma and Urine Thymidine and 2'-Deoxyuridine by LC-MS/MS for the Pharmacodynamic Evaluation of Erythrocyte Encapsulated Thymidine Phosphorylase in Patients with Mitochondrial Neurogastrointestinal Encephalomyopathy. 2020 Mar 13 1
6 32355481 Clinicopathology and Diagnosis Delay in a 40-Year-Old with Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE). 2020 Jan-Apr 2
7 32368563 Expression and Retention of Thymidine Phosphorylase in Cultured Reticulocytes as a Novel Treatment for MNGIE. 2020 Jun 12 1
8 30775048 Mitochondrial Neurogastrointestinal Encephalomyopathy Disease in Three Siblings from Pakistan with a Novel Mutation. 2019 Mar 1
9 31344955 Erythrocyte Encapsulated Thymidine Phosphorylase for the Treatment of Patients with Mitochondrial Neurogastrointestinal Encephalomyopathy: Study Protocol for a Multi-Centre, Multiple Dose, Open Label Trial. 2019 Jul 24 1
10 30285552 Development and validation of a quantitative method for thymidine phosphorylase activity in peripheral blood mononuclear cells. 2018 1
11 28765176 Transient clinical improvement of a mitochondrial neurogastrointestinal encephalomyopathy-like syndrome after allogeneic haematopoietic stem cell transplantation. 2017 Aug 1 3
12 25585305 Mitochondrial Neurogastrointestinal Encephalomyopathy Treated with Stem Cell Transplantation: A Case Report and Review of Literature. 2015 Jun 1
13 25881156 Anticancer activity of a thymidine quinoxaline conjugate is modulated by cytosolic thymidine pathways. 2015 Mar 21 3
14 26194912 Mitochondrial diseases caused by toxic compound accumulation: from etiopathology to therapeutic approaches. 2015 Oct 1
15 24407036 The kinetic mechanism of Human Thymidine Phosphorylase - a molecular target for cancer drug development. 2014 Mar 4 6
16 24562648 Thymidine phosphorylase influences [(18)F]fluorothymidine uptake in cancer cells and patients with non-small cell lung cancer. 2014 Jul 4
17 24777288 Variability of Proliferation and Diffusion in Different Lung Cancer Models as Measured by 3'-Deoxy-3'-¹⁸F-Fluorothymidine PET and Diffusion-Weighted MR Imaging. 2014 Jun 2
18 24802030 Liver as a source for thymidine phosphorylase replacement in mitochondrial neurogastrointestinal encephalomyopathy. 2014 1
19 21252618 Platelet derived endothelial cell growth factor/thymidine phosphorylase enhanced human IgE production. 2011 Mar 1
20 19654105 Thymidine kinase 1 and thymidine phosphorylase expression in non-small-cell lung carcinoma in relation to angiogenesis and proliferation. 2009 Nov 2
21 19824457 [Influence of the selected pyrimidine compounds on the activity of thymidine phosphorylase from normal and tumor endometrial cells]. 2009 Aug 1
22 19853446 Late-onset MNGIE without peripheral neuropathy due to incomplete loss of thymidine phosphorylase activity. 2009 Dec 2
23 18359286 Thymidine phosphorylase inhibits the expression of proapoptotic protein BNIP3. 2008 May 30 2
24 18600526 The role of platelet-derived endothelial cell growth factor/thymidine phosphorylase in tumor behavior. 2008 Jun 1
25 16721548 An evaluation of thymidine phosphorylase as a means of preventing thymidine rescue from the thymidylate synthase inhibitor raltitrexed. 2007 Feb 3
26 17544574 A novel ECGF1 mutation in a Thai patient with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE). 2007 Sep 1
27 17549623 Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE): biochemical features and therapeutic approaches. 2007 Jun 1
28 18221035 Thymidine phosphorylase (platelet-derived endothelial cell growth factor) as a target for capecitabine: from biology to the bedside. 2006 Jun 2
29 15975738 Thymidine phosphorylase mutations cause instability of mitochondrial DNA. 2005 Jul 18 1
30 16178026 Late-onset MNGIE due to partial loss of thymidine phosphorylase activity. 2005 Oct 2
31 14613972 ND5 is a hot-spot for multiple atypical mitochondrial DNA deletions in mitochondrial neurogastrointestinal encephalomyopathy. 2004 Jan 1 1
32 14717594 Role of histidine-85 in the catalytic mechanism of thymidine phosphorylase as assessed by targeted molecular dynamics simulations and quantum mechanical calculations. 2004 Jan 20 1
33 14720311 Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE): a disease of two genomes. 2004 Jan 1
34 15186830 Synthesis and evaluation of 6-methylene-bridged uracil derivatives. Part 2: optimization of inhibitors of human thymidine phosphorylase and their selectivity with uridine phosphorylase. 2004 Jul 1 1
35 12565833 Rapid disappearance of deoxyribose-1-phosphate in platelet derived endothelial cell growth factor/thymidine phosphorylase overexpressing cells. 2003 Feb 14 1
36 12644837 Role of platelet-derived endothelial cell growth factor/thymidine phosphorylase in fluoropyrimidine sensitivity. 2003 Mar 24 2
37 12813027 Site-specific somatic mitochondrial DNA point mutations in patients with thymidine phosphorylase deficiency. 2003 Jun 3
38 11733540 Altered thymidine metabolism due to defects of thymidine phosphorylase. 2002 Feb 8 3
39 11802215 Prognostic value of thymidine phosphorylase expression in breast carcinoma. 2002 Feb 1 2
40 12150947 Thymidine phosphorylase suppresses Fas-induced apoptotic signal transduction independent of its enzymatic activity. 2002 Jul 12 1
41 12174926 Thymidine phosphorylase and breast carcinoma. 2002 Jul-Aug 2
42 16120316 Mitochondrial neurogastrointestinal encephalomyopathy and thymidine metabolism: results and hypotheses. 2002 Nov 1
43 11641616 The expression of thymidine phosphorylase suppresses spontaneous apoptosis of cancer cells in esophageal squamous cell carcinoma. 2001 2
44 11761459 Thymidine phosphorylase as a target for imaging and therapy with thymine analogs. 2001 Nov 1
45 12188887 Thymidine phosphorylase: a two-face Janus in anticancer chemotherapy. 2001 Aug 1
46 10852545 Mitochondrial neurogastrointestinal encephalomyopathy: an autosomal recessive disorder due to thymidine phosphorylase mutations. 2000 Jun 1
47 10891120 Novel nonsubstrate inhibitors of human thymidine phosphorylase, a potential target for tumor-dependent angiogenesis. 2000 Jun 29 1
48 11099324 Gene expression for dihydropyrimidine dehydrogenase and thymidine phosphorylase influences outcome in epithelial ovarian cancer. 2000 Dec 1 2
49 10509545 Platelet-derived endothelial cell growth factor inhibits DNA synthesis in vascular smooth muscle cells. 1999 Sep 4
50 11504493 Thymidine phosphorylase: its role in sensitivity and resistance to anticancer drugs. 1999 Aug 1