7 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 33140501 | dUTPase inhibition confers susceptibility to a thymidylate synthase inhibitor in DNA-repair-defective human cancer cells. | 2021 Jan | 1 |
2 | 33824328 | Targeting nucleotide metabolism enhances the efficacy of anthracyclines and anti-metabolites in triple-negative breast cancer. | 2021 Apr 6 | 2 |
3 | 29748212 | TAS-114, a First-in-Class Dual dUTPase/DPD Inhibitor, Demonstrates Potential to Improve Therapeutic Efficacy of Fluoropyrimidine-Based Chemotherapy. | 2018 Aug | 1 |
4 | 24452393 | First-in-human, phase I dose-escalation study of single and multiple doses of a first-in-class enhancer of fluoropyrimidines, a dUTPase inhibitor (TAS-114) in healthy male volunteers. | 2014 Mar | 1 |
5 | 21780905 | Cellular response to efficient dUTPase RNAi silencing in stable HeLa cell lines perturbs expression levels of genes involved in thymidylate metabolism. | 2011 Jun | 1 |
6 | 19015155 | Regulation of human dUTPase gene expression and p53-mediated transcriptional repression in response to oxaliplatin-induced DNA damage. | 2009 Jan | 1 |
7 | 8162567 | Induction of resistance to fluorodeoxyuridine cytotoxicity and DNA damage in human tumor cells by expression of Escherichia coli deoxyuridinetriphosphatase. | 1994 May 1 | 1 |