Fluorouracil

Deoxyuridine triphosphatase ; Drosophila melanogaster







13 Article(s)
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1 33140501 dUTPase inhibition confers susceptibility to a thymidylate synthase inhibitor in DNA-repair-defective human cancer cells. 2021 Jan 1
2 28423595 dUTPase inhibition augments replication defects of 5-Fluorouracil. 2017 Apr 4 4
3 22339362 Discovery of a novel class of potent human deoxyuridine triphosphatase inhibitors remarkably enhancing the antitumor activity of thymidylate synthase inhibitors. 2012 Apr 12 2
4 22404301 Synthesis and discovery of N-carbonylpyrrolidine- or N-sulfonylpyrrolidine-containing uracil derivatives as potent human deoxyuridine triphosphatase inhibitors. 2012 Apr 12 1
5 21780905 Cellular response to efficient dUTPase RNAi silencing in stable HeLa cell lines perturbs expression levels of genes involved in thymidylate metabolism. 2011 Jun 1
6 19968781 dUTP pyrophosphatase expression correlates with a poor prognosis in hepatocellular carcinoma. 2010 Mar 1
7 19015155 Regulation of human dUTPase gene expression and p53-mediated transcriptional repression in response to oxaliplatin-induced DNA damage. 2009 Jan 2
8 19052026 Higher expression of deoxyuridine triphosphatase (dUTPase) may predict the metastasis potential of colorectal cancer. 2009 Apr 2
9 18790783 Novel opportunities for thymidylate metabolism as a therapeutic target. 2008 Sep 3
10 15269599 No anti-apoptotic effects of single copies of mutant p53 genes in drug-treated tumor cells. 2004 Aug 2
11 12096336 Novel gain of function activity of p53 mutants: activation of the dUTPase gene expression leading to resistance to 5-fluorouracil. 2002 Jul 11 2
12 10910061 dUTP nucleotidohydrolase isoform expression in normal and neoplastic tissues: association with survival and response to 5-fluorouracil in colorectal cancer. 2000 Jul 1 4
13 10567908 Expression of deoxyuridine triphosphatase (dUTPase) in colorectal tumours. 1999 Dec 22 1