Cyclosporine

cytochrome P450 family 3 subfamily A member 5 ; Homo sapiens







65 Article(s)
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1 35202484 PharmVar GeneFocus: CYP3A5. 2022 Feb 24 1
2 35629245 Evaluation of Pharmacogenetics of Drug-Metabolizing Enzymes and Drug Efflux Transporter in Renal Transplants Receiving Immunosuppressants. 2022 May 19 1
3 32162881 Severe Anaphylaxis During Allogeneic Hematopoietic Stem Cell Transplantation in a Patient with Aplastic Anemia: Case Report of Individualized Pharmaceutical Care and Literature Review. 2020 Mar 1 2
4 30378493 Metabolic Pathway of Cyclosporine A and Its Correlation with Nephrotoxicity. 2019 1
5 30520827 Switching Immunosuppression From Cyclosporine to Tacrolimus in Kidney Transplant Recipients Based on CYP3A5 Genotyping. 2019 Feb 1
6 31385766 Association Between CYP3A4 and CYP3A5 Genotypes and Cyclosporine's Blood Levels and Doses among Jordanian Kidney Transplanted Patients. 2019 3
7 29113387 Tacrolimus dose requirement based on the CYP3A5 genotype in renal transplant patients. 2017 Oct 6 3
8 29135906 Effect of Age and Allele Variants of CYP3A5, CYP3A4, and POR Genes on the Pharmacokinetics of Cyclosporin A in Pediatric Renal Transplant Recipients From Serbia. 2017 Dec 4
9 27310200 Risk Assessment of Drug-Drug Interactions of Calcineurin Inhibitors Affecting Sirolimus Pharmacokinetics in Renal Transplant Patients. 2016 Oct 1
10 27653228 Influence of Donor and Recipient CYP3A4, CYP3A5, and ABCB1 Genotypes on Clinical Outcomes and Nephrotoxicity in Liver Transplant Recipients. 2016 Oct 1
11 29441922 The impact of CYP3A5 on the metabolism of cyclosporine A and tacrolimus in the evaluation of efficiency and safety of immunosuppressive treatment in patients after kidney transplantation. 2016 Oct 1 2
12 25975003 Development and validation of a rapid and reliable real-time PCR method for CYP3A5 genotyping. 2015 1
13 25976223 CYP3A4∗18B and CYP3A5∗3 polymorphisms contribute to pharmacokinetic variability of cyclosporine among healthy Chinese subjects. 2015 Aug 30 2
14 26177348 Comparison of tacrolimus and cyclosporin A in CYP3A5 expressing Chinese de novo kidney transplant recipients: a 2-year prospective study. 2015 May 3
15 26271661 Personalizing initial calcineurin inhibitor dosing by adjusting to donor CYP3A-status in liver transplant patients. 2015 Dec 2
16 24369269 Successful telaprevir treatment in combination of cyclosporine against recurrence of hepatitis C in the Japanese liver transplant patients. 2014 1
17 24527031 Cyclosporine and herbal supplement interactions. 2014 1
18 24658827 The influence of CYP3A, PPARA, and POR genetic variants on the pharmacokinetics of tacrolimus and cyclosporine in renal transplant recipients. 2014 Jun 2
19 24691060 Association of CYP3A4*18B and CYP3A5*3 polymorphism with cyclosporine-related liver injury in Chinese renal transplant recipients. 2014 Jun 2
20 23557867 CYP3A4/5 polymorphisms affect the blood level of cyclosporine and tacrolimus in Chinese renal transplant recipients. 2013 Jun 1
21 21896346 Polymorphisms in genes that regulate cyclosporine metabolism affect cyclosporine blood levels and clinical outcomes in patients who receive allogeneic hematopoietic stem cell transplantation. 2012 Jan 2
22 22205779 Cyclosporine A- and tacrolimus-mediated inhibition of CYP3A4 and CYP3A5 in vitro. 2012 Apr 3
23 22947591 CYP3A5 polymorphism effect on cyclosporine pharmacokinetics in living donor renal transplant recipients: analysis by population pharmacokinetics. 2012 Sep 4
24 23018254 Impact of CYP3A4*1B and CYP3A5*3 polymorphisms on the pharmacokinetics of cyclosporine and sirolimus in renal transplant recipients. 2012 Jul-Sep 4
25 23085740 Association of CYP3A polymorphisms with the pharmacokinetics of cyclosporine A in early post-renal transplant recipients in China. 2012 Dec 3
26 23217392 CYP3A4 genetic polymorphisms predict cyclosporine-related clinical events in Chinese renal transplant recipients. 2012 Dec 1
27 20368718 The effect of CYP3A5 polymorphism on dose-adjusted cyclosporine concentration in renal transplant recipients: a meta-analysis. 2011 Jun 2
28 21102498 Cytochrome P450 genetic polymorphisms influence the serum concentration of calcineurin inhibitors in allogeneic hematopoietic SCT recipients. 2011 Aug 1
29 21383650 Polymorphisms in CYP3A5, CYP3A4, and ABCB1 are not associated with cyclosporine pharmacokinetics nor with cyclosporine clinical end points after renal transplantation. 2011 Apr 2
30 21806386 Pharmacogenetics of calcineurin inhibitors in Brazilian renal transplant patients. 2011 Sep 2
31 21839244 Pharmacogenetic study of ABCB1 and CYP3A5 genes during the first year following heart transplantation regarding tacrolimus or cyclosporine levels. 2011 Jul-Aug 2
32 21857093 Influence of ABCB1, CYP3A4*18B and CYP3A5*3 polymorphisms on cyclosporine A pharmacokinetics in bone marrow transplant recipients. 2011 3
33 20170205 Effect of CYP3A and ABCB1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part I. 2010 Mar 2
34 20214406 Effect of CYP3A and ABCB1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part II. 2010 Apr 1
35 20588203 Effects of the CYP3A5*3 variant on cyclosporine exposure and acute rejection rate in renal transplant patients: a meta-analysis. 2010 Sep 2
36 18936931 Effect of genetic polymorphisms of CYP3A5 and MDR1 on cyclosporine concentration during the early stage after renal transplantation in Chinese patients co-treated with diltiazem. 2009 Mar 1
37 19343327 Impact of CYP3A5 and CYP3A4 gene polymorphisms on dose requirement of calcineurin inhibitors, cyclosporine and tacrolimus, in renal allograft recipients of North India. 2009 Aug 1
38 19376366 Genetic polymorphisms in CYP3A5 and MDR1 genes and their correlations with plasma levels of tacrolimus and cyclosporine in renal transplant recipients. 2009 Apr 1
39 19667964 Pharmacogenetics of calcineurin inhibitors in renal transplantation. 2009 Aug 15 1
40 19925383 Influence of the MDR1 haplotype and CYP3A5 genotypes on cyclosporine blood level in Chinese renal transplant recipients. 2009 Dec 3
41 20038391 [Pharmacogenetic analysis of the absorption kinetics of cyclosporine in a population of Spanish cardiac transplant patients]. 2009 Nov-Dec 1
42 18180803 CYP3A5 genotype is associated with longer patient survival after kidney transplantation and long-term treatment with cyclosporine. 2008 Dec 2
43 18518855 A drug transporter for all ages? ABCB1 and the developmental pharmacogenetics of cyclosporine. 2008 Jun 1
44 18589174 Significant impact of gene polymorphisms on tacrolimus but not cyclosporine dosing in Asian renal transplant recipients. 2008 Jun 2
45 18636247 Association of MDR1, CYP3A4*18B, and CYP3A5*3 polymorphisms with cyclosporine pharmacokinetics in Chinese renal transplant recipients. 2008 Nov 2
46 18978522 CYP3A7, CYP3A5, CYP3A4, and ABCB1 genetic polymorphisms, cyclosporine concentration, and dose requirement in transplant recipients. 2008 Dec 4
47 19005401 Haplotypic structure of ABCB1/MDR1 gene modifies the risk of the acute allograft rejection in renal transplant recipients. 2008 Nov 15 1
48 17151193 Metabolism of sirolimus in the presence or absence of cyclosporine by genotyped human liver microsomes and recombinant cytochromes P450 3A4 and 3A5. 2007 Mar 1
49 17425754 Multi-drug resistance gene-1 (MDR-1) haplotypes and the CYP3A5*1 genotype have no influence on ciclosporin dose requirements as assessed by C0 or C2 measurements. 2007 Mar-Apr 1
50 18240909 Cytochrome P450 3A polymorphisms and immunosuppressive drugs: an update. 2007 Jul 1