3-(carbamoylamino)-5-(3-fluorophenyl)-N-(3-piperidyl)thiophene-2-carboxamide

tumor protein p53 ; Homo sapiens







8 Article(s)
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1 28228262 Targeting DNA Damage Response in Prostate Cancer by Inhibiting Androgen Receptor-CDC6-ATR-Chk1 Signaling. 2017 Feb 21 2
2 25349305 Combined CDKN1A/TP53 mutation in bladder cancer is a therapeutic target. 2015 Jan 1
3 23544166 DW-MRI as a Predictive Biomarker of Radiosensitization of GBM through Targeted Inhibition of Checkpoint Kinases. 2013 Apr 1
4 23839309 Chk1/2 inhibition overcomes the cisplatin resistance of head and neck cancer cells secondary to the loss of functional p53. 2013 Sep 1
5 22653969 The checkpoint kinase inhibitor AZD7762 potentiates chemotherapy-induced apoptosis of p53-mutated multiple myeloma cells. 2012 Aug 3
6 22825736 The Chk1 inhibitor AZD7762 sensitises p53 mutant breast cancer cells to radiation in vitro and in vivo. 2012 Oct 3
7 22134241 Selective radiosensitization of p53 mutant pancreatic cancer cells by combined inhibition of Chk1 and PARP1. 2011 Dec 15 3
8 20233881 In vitro and in vivo radiation sensitization of human tumor cells by a novel checkpoint kinase inhibitor, AZD7762. 2010 Apr 1 2