| 1 |
30833076 | Kruppel-like factor 2 mediated anti-proliferative and anti-metastasis effects of simvastatin in p53 mutant colon cancer. | 2019 Apr 16 |
3 |
| 2 |
31892709 | Therapeutic effects of statins against lung adenocarcinoma via p53 mutant-mediated apoptosis. | 2019 Dec 31 |
3 |
| 3 |
25727911 | Downregulation of miR-146a, cyclooxygenase-2 and advanced glycation end-products in simvastatin-treated older patients with hyperlipidemia. | 2016 Mar |
1 |
| 4 |
25412322 | Simvastatin induces growth inhibition and apoptosis in HepG2 and Huh7 hepatocellular carcinoma cells via upregulation of Notch1 expression. | 2015 Mar |
1 |
| 5 |
23354132 | Phosphorylation of eIF2α attenuates statin-induced apoptosis by inhibiting the stabilization and translocation of p53 to the mitochondria. | 2013 Mar |
1 |
| 6 |
23583370 | Simvastatin induced HCT116 colorectal cancer cell apoptosis through p38MAPK-p53-survivin signaling cascade. | 2013 Aug |
6 |
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23933099 | Simvastatin rises reactive oxygen species levels and induces senescence in human melanoma cells by activation of p53/p21 pathway. | 2013 Nov 15 |
4 |
| 8 |
20946258 | Simvastatin inhibits glucose-stimulated vascular smooth muscle cell migration involving increased expression of RhoB and a block of Ras/Akt signal. | 2012 Apr |
1 |
| 9 |
22052376 | The pleiotropic effects of statins in the prevention of atherosclerosis : Editorial to: "Simvastatin suppresses apoptosis in vulnerable atherosclerotic plaques through regulating the expression of p53, Bcl-2 en Bcl-xL" by Weiwei Qin et al. | 2012 Feb |
1 |
| 10 |
20467885 | Simvastatin enhances irinotecan-induced apoptosis in human non-small cell lung cancer cells by inhibition of proteasome activity. | 2011 Oct |
1 |
| 11 |
21199873 | Simvastatin prevents skeletal metastasis of breast cancer by an antagonistic interplay between p53 and CD44. | 2011 Apr 1 |
1 |
| 12 |
21304979 | Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: a dual role for p53. | 2011 Jan 31 |
5 |
| 13 |
20043868 | Stabilization and translocation of p53 to mitochondria is linked to Bax translocation to mitochondria in simvastatin-induced apoptosis. | 2010 Jan 22 |
4 |
| 14 |
20045437 | Statin-triggered cell death in primary human lung mesenchymal cells involves p53-PUMA and release of Smac and Omi but not cytochrome c. | 2010 Apr |
4 |
| 15 |
18804536 | Simvastatin inhibits cell cycle progression in glucose-stimulated proliferation of aortic vascular smooth muscle cells by up-regulating cyclin dependent kinase inhibitors and p53. | 2008 Sep-Oct |
3 |
| 16 |
17125918 | Simvastatin induces apoptosis in human breast cancer cells: p53 and estrogen receptor independent pathway requiring signalling through JNK. | 2007 Jun 8 |
1 |
| 17 |
15625077 | HMG-CoA reductase inhibitors, statins, induce phosphorylation of Mdm2 and attenuate the p53 response to DNA damage. | 2005 Mar |
1 |