Lovastatin

tumor protein p53 ; Homo sapiens







14 Article(s)
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1 33987937 Lovastatin reduces PEL cell survival by phosphorylating ERK1/2 that blocks the autophagic flux and engages a cross-talk with p53 to activate p21. 2021 Jul 2
2 31821701 Lovastatin-mediated MCF-7 cancer cell death involves LKB1-AMPK-p38MAPK-p53-survivin signalling cascade. 2020 Jan 6
3 30939155 Regulatory mechanisms of fluvastatin and lovastatin for the p21 induction in human cervical cancer HeLa cells. 2019 1
4 23271636 Lovastatin protects chondrocytes derived from Wharton's jelly of human cord against hydrogen-peroxide-induced in vitro injury. 2013 Mar 1
5 21883038 Anti-cancer characteristics of mevinolin against three different solid tumor cell lines was not solely p53-dependent. 2012 Oct 2
6 20298590 Lovastatin induces apoptosis of ovarian cancer cells and synergizes with doxorubicin: potential therapeutic relevance. 2010 Mar 18 1
7 18034278 In vitro mechanisms of lovastatin on lung cancer cell lines as a potential chemopreventive agent. 2008 Jan-Feb 1
8 16467108 Lovastatin protects human endothelial cells from killing by ionizing radiation without impairing induction and repair of DNA double-strand breaks. 2006 Feb 1 1
9 17088865 Lovastatin protects human endothelial cells from the genotoxic and cytotoxic effects of the anticancer drugs doxorubicin and etoposide. 2006 Dec 1
10 14672267 Cell-cycle gene expression in lovastatin-induced medulloblastoma apoptosis. 2003 Nov 3
11 11307620 Lovastatin and phenylacetate induce apoptosis, but not differentiation, in human malignant glioma cells. 2001 Mar 3
12 11720884 Lovastatin-induced apoptosis in thyroid cells: involvement of cytochrome c and lamin B. 2001 Nov 1
13 9811471 Lovastatin mediated G1 arrest in normal and tumor breast cells is through inhibition of CDK2 activity and redistribution of p21 and p27, independent of p53. 1998 Nov 5 2
14 8018562 Expression of wild-type p53 during the cell cycle in normal human mammary epithelial cells. 1994 Mar 1