olaparib

tumor protein p53 ; Homo sapiens







19 Article(s)
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1 35086956 Olaparib-Induced Senescence Is Bypassed through G2-M Checkpoint Override in Olaparib-Resistant Prostate Cancer. 2022 Apr 1 1
2 35163037 Sesquiterpene Lactones Potentiate Olaparib-Induced DNA Damage in p53 Wildtype Cancer Cells. 2022 Jan 20 2
3 35269669 Possible Action of Olaparib for Preventing Invasion of Oral Squamous Cell Carcinoma In Vitro and In Vivo. 2022 Feb 25 1
4 33236159 PARP inhibitor resistance and TP53 mutations in patients treated with olaparib for BRCA-mutated cancer: Four case reports. 2021 Jan 5
5 33970096 Rapid Response of a BRCA2/TP53/PTEN-Deleted Metastatic Uterine Leiomyosarcoma to Olaparib: A Case Report. 2021 May 1
6 34638899 Metformin Affects Olaparib Sensitivity through Induction of Apoptosis in Epithelial Ovarian Cancer Cell Lines. 2021 Sep 29 1
7 32526907 Identifying and Overcoming Mechanisms of PARP Inhibitor Resistance in Homologous Recombination Repair-Deficient and Repair-Proficient High Grade Serous Ovarian Cancer Cells. 2020 Jun 9 1
8 30740957 Olaparib induced senescence under P16 or P53 dependent manner in ovarian cancer. 2019 Mar 3
9 29511347 PARP-1 inhibition with or without ionizing radiation confers reactive oxygen species-mediated cytotoxicity preferentially to cancer cells with mutant TP53. 2018 May 1
10 29783721 AZD1775 Increases Sensitivity to Olaparib and Gemcitabine in Cancer Cells with p53 Mutations. 2018 May 19 1
11 28069876 Targeting Plk1 to Enhance Efficacy of Olaparib in Castration-Resistant Prostate Cancer. 2017 Mar 1
12 28182994 ATM-Deficient Colorectal Cancer Cells Are Sensitive to the PARP Inhibitor Olaparib. 2017 Apr 1
13 28223274 Long-Term Responders on Olaparib Maintenance in High-Grade Serous Ovarian Cancer: Clinical and Molecular Characterization. 2017 Aug 1 1
14 26975633 APR-246 (PRIMA-1(MET)) strongly synergizes with AZD2281 (olaparib) induced PARP inhibition to induce apoptosis in non-small cell lung cancer cell lines. 2016 Jun 1 3
15 27686740 Efficacy of poly (ADP-ribose) polymerase inhibitor olaparib against head and neck cancer cells: Predictions of drug sensitivity based on PAR-p53-NF-κB interactions. 2016 Nov 16 4
16 24694947 New insights into PARP inhibitors' effect on cell cycle and homology-directed DNA damage repair. 2014 Jun 5
17 24841718 Low ATM protein expression and depletion of p53 correlates with olaparib sensitivity in gastric cancer cell lines. 2014 2
18 22416035 Enhanced cytotoxicity of PARP inhibition in mantle cell lymphoma harbouring mutations in both ATM and p53. 2012 Jun 4
19 22134241 Selective radiosensitization of p53 mutant pancreatic cancer cells by combined inhibition of Chk1 and PARP1. 2011 Dec 15 5