pifithrin

tumor protein p53 ; Homo sapiens







240 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
51 29802837 Activated mitochondrial apoptosis in hESCs after dissociation involving the PKA/p-p53/Bax signaling pathway. 2018 Aug 15 2
52 29944886 Down-regulation of LHPP in cervical cancer influences cell proliferation, metastasis and apoptosis by modulating AKT. 2018 Sep 5 1
53 30080692 VX-680 induces p53-mediated apoptosis in human cholangiocarcinoma cells. 2018 Nov 1
54 30103008 Activation of p53 by costunolide blocks glutaminolysis and inhibits proliferation in human colorectal cancer cells. 2018 Dec 15 1
55 30272369 JIB‑04 induces cell apoptosis via activation of the p53/Bcl‑2/caspase pathway in MHCC97H and HepG2 cells. 2018 Dec 2
56 30545932 Zinc deficiency causes neural tube defects through attenuation of p53 ubiquitylation. 2018 Dec 13 1
57 31938352 High glucose concentration induces retinal endothelial cell apoptosis by activating p53 signaling pathway. 2018 1
58 28028695 5-Fluorouracil inhibits cell migration by induction of Sestrin2 in colon cancer cells. 2017 Feb 2
59 28035355 Scutellarin suppresses growth and causes apoptosis of human colorectal cancer cells by regulating the p53 pathway. 2017 Feb 1
60 28098861 Triptolide inhibits viability and induces apoptosis in liver cancer cells through activation of the tumor suppressor gene p53. 2017 Mar 1
61 28143426 The marine triterpene glycoside frondoside A induces p53-independent apoptosis and inhibits autophagy in urothelial carcinoma cells. 2017 Feb 1 2
62 28321407 PTEN Reduced UVB-Mediated Apoptosis in Retinal Pigment Epithelium Cells. 2017 3
63 28431961 Ionizing radiation induces long-term senescence in endothelial cells through mitochondrial respiratory complex II dysfunction and superoxide generation. 2017 Jul 1
64 28631571 A truncated p53 in human lung cancer cells as a critical determinant of proliferation and invasiveness. 2017 Jun 1
65 28691888 Signal-Regulated Protein Kinases/Protein Kinase B-p53-BH3-Interacting Domain Death Agonist Pathway Regulates Gingipain-Induced Apoptosis in Osteoblasts. 2017 Nov 1
66 28990231 IFI16 restoration in hepatocellular carcinoma induces tumour inhibition via activation of p53 signals and inflammasome. 2017 Dec 2
67 29039478 Phosphorylation of eIF2α suppresses cisplatin-induced p53 activation and apoptosis by attenuating oxidative stress via ATF4-mediated HO-1 expression in human renal proximal tubular cells. 2017 Dec 1
68 29212215 Betanodavirus B2 protein triggers apoptosis and necroptosis in lung cancer cells that suppresses autophagy. 2017 Nov 7 2
69 32719725 Anti-proliferative effect and cell cycle arrest induced by saponins extracted from tea (Camellia sinensis) flower in human ovarian cancer cells. 2017 Oct 1
70 26636375 Tetraploidization or autophagy: The ultimate fate of senescent human endometrial stem cells under ATM or p53 inhibition. 2016 1
71 27064011 Preclinical effects of honokiol on treating glioblastoma multiforme via G1 phase arrest and cell apoptosis. 2016 May 15 1
72 27270209 Modulation of oxidative stress and subsequent induction of apoptosis and endoplasmic reticulum stress allows citral to decrease cancer cell proliferation. 2016 Jun 8 1
73 27327234 Artesunate induces ROS-dependent apoptosis via a Bax-mediated intrinsic pathway in Huh-7 and Hep3B cells. 2016 Oct 1 2
74 27402273 A novel alkaloid, evodiamine causes nuclear localization of cytochrome-c and induces apoptosis independent of p53 in human lung cancer cells. 2016 Sep 2 2
75 27470413 Directional modification of chrysin for exerting apoptosis and enhancing significantly anti-cancer effects of 10-hydroxy camptothecin. 2016 Aug 1
76 27471307 Platelet-Derived Growth Factor-BB Protects Mesenchymal Stem Cells (MSCs) Derived From Immune Thrombocytopenia Patients Against Apoptosis and Senescence and Maintains MSC-Mediated Immunosuppression. 2016 Dec 1
77 27555286 New antiproliferative 7-(4-(N-substituted carbamoylmethyl)piperazin-1-yl) derivatives of ciprofloxacin induce cell cycle arrest at G2/M phase. 2016 Oct 1 1
78 27591796 The antioxidant transcription factor Nrf2 contributes to the protective effect of mild thermotolerance (40°C) against heat shock-induced apoptosis. 2016 Oct 1
79 25435953 Long intergenic non-coding RNA induced by X-ray irradiation regulates DNA damage response signaling in the human bronchial epithelial BEAS-2B cell line. 2015 Jan 2
80 25544361 Nutlin-3-induced redistribution of chromatin-bound IFI16 in human hepatocellular carcinoma cells in vitro is associated with p53 activation. 2015 Feb 1
81 25565771 Arsenic sulfide, the main component of realgar, a traditional Chinese medicine, induces apoptosis of gastric cancer cells in vitro and in vivo. 2015 1
82 25575314 Studies on antitumor mechanism of two planar platinum(II) complexes with 8-hydroxyquinoline: synthesis, characterization, cytotoxicity, cell cycle and apoptosis. 2015 Mar 6 2
83 25641429 Flavokawain B inhibits the growth of acute lymphoblastic leukemia cells via p53 and caspase-dependent mechanisms. 2015 2
84 25658320 Calpain-3 impairs cell proliferation and stimulates oxidative stress-mediated cell death in melanoma cells. 2015 1
85 25713322 p53 protects against LPS-induced lung endothelial barrier dysfunction. 2015 Apr 15 1
86 25737737 Shikonin Induces Apoptosis, Necrosis, and Premature Senescence of Human A549 Lung Cancer Cells through Upregulation of p53 Expression. 2015 2
87 25793965 Scopadulciol, Isolated from Scoparia dulcis, Induces β-Catenin Degradation and Overcomes Tumor Necrosis Factor-Related Apoptosis Ligand Resistance in AGS Human Gastric Adenocarcinoma Cells. 2015 Apr 24 1
88 25938491 Novel Pactamycin Analogs Induce p53 Dependent Cell-Cycle Arrest at S-Phase in Human Head and Neck Squamous Cell Carcinoma (HNSCC) Cells. 2015 1
89 25955698 Doxorubicin impairs the insulin-like growth factor-1 system and causes insulin-like growth factor-1 resistance in cardiomyocytes. 2015 1
90 26170659 Comparative assessment of the apoptotic potential of silver nanoparticles synthesized by Bacillus tequilensis and Calocybe indica in MDA-MB-231 human breast cancer cells: targeting p53 for anticancer therapy. 2015 1
91 26250568 Magnolol inhibits growth of gallbladder cancer cells through the p53 pathway. 2015 Oct 2
92 26302161 Inhibition of p53 attenuates ischemic stress-induced activation of astrocytes. 2015 Sep 30 2
93 26434996 Dual regulation of energy metabolism by p53 in human cervix and breast cancer cells. 2015 Dec 1
94 26703711 Activation of the Mitochondrial Apoptotic Signaling Platform during Rubella Virus Infection. 2015 Nov 26 1
95 24120424 Role of p53 in the cellular response following oleic acid accumulation in Chang liver cells. 2014 Jan 3 1
96 24343341 The mitochondrial cyclophilin D/p53 complexation mediates doxorubicin-induced non-apoptotic death of A549 lung cancer cells. 2014 Apr 2
97 24646317 p53 functional inhibitors behaving like pifithrin-β counteract the Alzheimer peptide non-β-amyloid component effects in human SH-SY5Y cells. 2014 May 21 1
98 24667845 Heat stress induces apoptosis through transcription-independent p53-mediated mitochondrial pathways in human umbilical vein endothelial cell. 2014 Mar 26 2
99 24726874 Aspirin-induced inhibition of adipogenesis was p53-dependent and associated with inactivation of pentose phosphate pathway. 2014 Sep 5 2
100 24743574 Curcumin significantly enhances dual PI3K/Akt and mTOR inhibitor NVP-BEZ235-induced apoptosis in human renal carcinoma Caki cells through down-regulation of p53-dependent Bcl-2 expression and inhibition of Mcl-1 protein stability. 2014 1