Paclitaxel

tumor protein p53 ; Homo sapiens







240 Article(s)
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101 19363466 Paclitaxel combined with siRNA targeting HPV16 oncogenes improves cytotoxicity for cervical carcinoma. 2009 Oct 1
102 19397590 Arsenic trioxide suppresses paclitaxel-induced mitotic arrest. 2009 Jun 1
103 19421315 MYC prevents apoptosis and enhances endoreduplication induced by paclitaxel. 2009 2
104 19815708 The stent-eluting drugs sirolimus and paclitaxel suppress healing of the endothelium by induction of autophagy. 2009 Nov 1
105 17960385 The effect of p53 gene expression on the inhibition of cell proliferation by paclitaxel. 2008 Aug 4
106 18158619 Id-1 regulates Bcl-2 and Bax expression through p53 and NF-kappaB in MCF-7 breast cancer cells. 2008 Nov 1
107 18205918 Quantitative image analysis of intra-tumoral bFGF level as a molecular marker of paclitaxel resistance. 2008 Jan 18 1
108 18319335 Modulation of drug resistance by artificial transcription factors. 2008 Mar 1
109 18469851 Mechanism of G1-like arrest by low concentrations of paclitaxel: next cell cycle p53-dependent arrest with sub G1 DNA content mediated by prolonged mitosis. 2008 Jul 24 2
110 18506998 Adenovirus-mediated inhibitor kappaB gene transfer improves the chemosensitivity to anticancer drugs in human lung cancer in vitro and in vivo. 2008 Mar-Apr 1
111 18516295 Cyclic pifithrin-alpha sensitizes wild type p53 tumor cells to antimicrotubule agent-induced apoptosis. 2008 Jun 3
112 18555006 p19(ras) amplifies p73beta-induced apoptosis through mitochondrial pathway. 2008 Aug 15 1
113 18806740 Differential effects of low and high doses of Taxol in anaplastic thyroid cancer cells: possible implication of the Pin1 prolyl isomerase. 2008 Sep 1
114 18813780 Low doses of paclitaxel potently induce apoptosis in human retinoblastoma Y79 cells by up-regulating E2F1. 2008 Oct 1
115 18971636 RHAMM is differentially expressed in the cell cycle and downregulated by the tumor suppressor p53. 2008 Nov 1 1
116 19000447 [Correlation of expression of P-glycoprotein and inhibitor of apoptosis proteins to chemosensitivity in gastrointestinal carcinoma tissues]. 2008 Nov 1
117 20731894 [Effects of p53 gene on drug resistance in human lung cancer cell lines.]. 2008 Apr 20 1
118 17244262 Additive cytotoxic effect of apoptin and chemotherapeutic agents paclitaxel and etoposide on human tumour cells. 2007 Feb 3
119 17636258 Activation of targeted necrosis by a p53 peptide: a novel death pathway that circumvents apoptotic resistance. 2007 Sep 14 1
120 17686239 [The predictive factors for the response to platinum/paclitaxel based first-line adjuvant chemotherapy in advanced ovarian cancer]. 2007 May 8 1
121 17823933 Paclitaxel enhanced radiation sensitization for the suppression of human prostate cancer tumor growth via a p53 independent pathway. 2007 Nov 1 6
122 17912033 Replication stress, defective S-phase checkpoint and increased death in Plk2-deficient human cancer cells. 2007 Oct 15 1
123 18231754 The relationship between p38MAPK and apoptosis during paclitaxel resistance of ovarian cancer cells. 2007 Dec 1
124 15990222 Induction of p53 and drug resistance following treatment with cisplatin or paclitaxel in ovarian cancer cell lines. 2006 May 18 2
125 16356831 2-Methoxyestradiol and paclitaxel have similar effects on the cell cycle and induction of apoptosis in prostate cancer cells. 2006 Jan 8 1
126 16364249 TP53 and P21 polymorphisms: response to cisplatinum/paclitaxel-based chemotherapy in ovarian cancer. 2006 Feb 3 1
127 16459017 Prognostic significance of p53 mutation in suboptimally resected advanced ovarian carcinoma treated with the combination chemotherapy of paclitaxel and carboplatin. 2006 Sep 28 1
128 16616141 Evidence that low doses of Taxol enhance the functional transactivatory properties of p53 on p21 waf promoter in MCF-7 breast cancer cells. 2006 Apr 17 3
129 16687915 Prolonged mitosis versus tetraploid checkpoint: how p53 measures the duration of mitosis. 2006 May 1
130 16739339 P53 gene status in patients with advanced serous epithelial ovarian cancer in relation to response to paclitaxel- plus platinum-based chemotherapy and long-term clinical outcome. 2006 Jan-Feb 2
131 16820892 Growth inhibition and apoptosis induction in ovarian cancer cells. 2006 Aug 1
132 17166391 [Routine chemotherapeutic drug treatment effectiveness predictive molecules and chemotherapeutic drug selection]. 2006 Dec 1
133 15592521 A novel CYR61-triggered 'CYR61-alphavbeta3 integrin loop' regulates breast cancer cell survival and chemosensitivity through activation of ERK1/ERK2 MAPK signaling pathway. 2005 Jan 27 2
134 15657900 Pharmacological and small interference RNA-mediated inhibition of breast cancer-associated fatty acid synthase (oncogenic antigen-519) synergistically enhances Taxol (paclitaxel)-induced cytotoxicity. 2005 May 20 2
135 15662138 The tumor suppressor p33ING1b enhances taxol-induced apoptosis by p53-dependent pathway in human osteosarcoma U2OS cells. 2005 Jan 3
136 15691646 Prognostic value of the epidermal growth factor receptor (EGRF) and p53 in advanced head and neck squamous cell carcinoma patients treated with induction chemotherapy. 2005 Feb 1
137 15711598 Apoptosis of non-small-cell lung cancer cell lines after paclitaxel treatment involves the BH3-only proapoptotic protein Bim. 2005 Mar 1
138 15746064 Patupilone acts as radiosensitizing agent in multidrug-resistant cancer cells in vitro and in vivo. 2005 Feb 15 1
139 15863265 Paclitaxel/Taxol sensitivity in human renal cell carcinoma is not determined by the p53 status. 2005 May 26 2
140 15870870 Apoptosis induced by 5-fluorouracil, cisplatin and paclitaxel are associated with p53 gene status in gastric cancer cell lines. 2005 Jun 3
141 15908516 Chemotherapy compounds in cervical cancer cells primed by reconstitution of p53 function after short interfering RNA-mediated degradation of human papillomavirus 18 E6 mRNA: opposite effect of siRNA in combination with different drugs. 2005 Aug 1
142 16122187 Relationship between chemotherapy with paclitaxel, cisplatin, vinorelbine and titanocene dichloride and expression of proliferation markers and tumour suppressor gene p53 in human ovarian cancer xenografts in nude mice. 2005 1
143 16127286 p53 Gene status and response to topotecan-containing chemotherapy in advanced ovarian carcinoma. 2005 1
144 15012603 Regulation of estrogen receptor-alpha expression in MCF-7 cells by taxol. 2004 Mar 1
145 15031599 Mechanisms of paclitaxel-induced apoptosis in an ovarian cancer cell line and its paclitaxel-resistant clone. 2004 1
146 15159015 Insulin can modulate MCF-7 cell response to paclitaxel. 2004 Jun 25 1
147 15467449 The cyclin-dependent kinase inhibitor p21(CIP1/WAF1) blocks paclitaxel-induced G2M arrest and attenuates mitochondrial injury and apoptosis in p53-null human leukemia cells. 2004 Oct 1
148 15475475 High-content screening with siRNA optimizes a cell biological approach to drug discovery: defining the role of P53 activation in the cellular response to anticancer drugs. 2004 Oct 1
149 15486197 Antiangiogenic activity of paclitaxel is associated with its cytostatic effect, mediated by the initiation but not completion of a mitochondrial apoptotic signaling pathway. 2004 Oct 1
150 12518324 Experimental therapy of human prostate cancer by inhibiting MDM2 expression with novel mixed-backbone antisense oligonucleotides: in vitro and in vivo activities and mechanisms. 2003 Feb 15 1