Fluorouracil

tumor protein p53 ; Homo sapiens







354 Article(s)
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201 18930000 Rare sugar D-allose enhances anti-tumor effect of 5-fluorouracil on the human hepatocellular carcinoma cell line HuH-7. 2008 Sep 1
202 19189638 Role of caspases in 5-FU and selenium-induced growth inhibition of colorectal cancer cells. 2008 Nov-Dec 1
203 20020938 CAS Enhances Chemotherapeutic Drug-Induced p53 Accumulation and Apoptosis: Use of CAS for High-Sensitivity Anticancer Drug Screening. 2008 Jan 1
204 20731894 [Effects of p53 gene on drug resistance in human lung cancer cell lines.]. 2008 Apr 20 2
205 21479491 Role of ASC in hypoxia-mediated cell death in pancreatic cancer. 2008 Nov-Dec 1
206 17056233 Inhibition of Fas expression by RNAi modulates 5-fluorouracil-induced apoptosis in HCT116 cells expressing wild-type p53. 2007 Jan 3
207 17063488 Gadd45alpha does not modulate the carboplatin or 5-fluorouracil-induced apoptosis in human papillomavirus-positive cells. 2007 Apr 1 1
208 17119966 Mechanisms of acquired chemoresistance to 5-fluorouracil and tomudex: thymidylate synthase dependent and independent networks. 2007 May 2
209 17237273 The role of spermidine/spermine N1-acetyltransferase in determining response to chemotherapeutic agents in colorectal cancer cells. 2007 Jan 1
210 17242401 5-fluorouracil activation of p53 involves an MDM2-ribosomal protein interaction. 2007 Mar 16 8
211 17275163 Synergy of interferon-alpha and 5-fluorouracil in human renal cell carcinoma requires p53 activity. 2007 Oct 7
212 17327702 Distinct roles of MDMX in the regulation of p53 response to ribosomal stress. 2007 Jan 15 1
213 17339891 Changes in the status of p53 affect drug sensitivity to thymidylate synthase (TS) inhibitors by altering TS levels. 2007 Mar 12 2
214 17499351 Vitamin E analogues as a novel group of mitocans: anti-cancer agents that act by targeting mitochondria. 2007 Oct-Dec 1
215 17634554 Regulation of p53 expression in response to 5-fluorouracil in human cancer RKO cells. 2007 Jul 15 13
216 17725105 Schedule-dependent cytotoxicity of 5-fluorouracil and irinotecan in p53 mutant human colon cancer. 2007 Jun 2
217 17971768 Combination therapy with PEG-IFN-alpha and 5-FU inhibits HepG2 tumour cell growth in nude mice by apoptosis of p53. 2007 Dec 3 3
218 17982676 Apoptosis, cell cycle progression and gene expression in TP53-depleted HCT116 colon cancer cells in response to short-term 5-fluorouracil treatment. 2007 Dec 17
219 16434701 Regulation of the human p21(waf1/cip1) gene promoter via multiple binding sites for p53 and the vitamin D3 receptor. 2006 1
220 16470928 [Relation between mutant p53 and multidrug resistance in gastric cancer]. 2006 Jan 1
221 16528528 Gene expression of ferredoxin reductase predicts outcome in patients with metastatic colorectal cancer treated by 5-fluorouracil plus leucovorin. 2006 Dec 4
222 16557594 Transcriptional profiling of MCF7 breast cancer cells in response to 5-Fluorouracil: relationship with cell cycle changes and apoptosis, and identification of novel targets of p53. 2006 Sep 1 1
223 16584912 Relationship between p53 status and 5-fluorouracil sensitivity in 3 cell lines. 2006 Jul 14 1
224 16631755 Protein kinase PKC delta and c-Abl are required for mitochondrial apoptosis induction by genotoxic stress in the absence of p53, p73 and Fas receptor. 2006 May 15 1
225 16652156 Functional connection between p53 and caspase-2 is essential for apoptosis induced by DNA damage. 2006 Sep 14 1
226 16686938 Genetic dissection of apoptosis and cell cycle control in response of colorectal cancer treated with preoperative radiochemotherapy. 2006 May 10 3
227 16709241 Cellular response to 5-fluorouracil (5-FU) in 5-FU-resistant colon cancer cell lines during treatment and recovery. 2006 May 18 2
228 16818496 Pharmacogenetics of anticancer drug sensitivity in pancreatic cancer. 2006 Jun 1
229 16931914 Cross-talks in the p53 family: deltaNp63 is an anti-apoptotic target for deltaNp73alpha and p53 gain-of-function mutants. 2006 Sep 1
230 16963839 Transcriptional activation of the carboxylesterase 2 gene by the p53 pathway. 2006 Nov 11
231 17207318 5-fluorouracil mediates apoptosis and G1/S arrest in laryngeal squamous cell carcinoma via a p53-independent pathway. 2006 Nov-Dec 8
232 15365767 Docosahexaenoic acid enhances the susceptibility of human colorectal cancer cells to 5-fluorouracil. 2005 Jan 2
233 15546879 Combination of 5-fluorouracil and N1,N11-diethylnorspermine markedly activates spermidine/spermine N1-acetyltransferase expression, depletes polyamines, and synergistically induces apoptosis in colon carcinoma cells. 2005 Feb 4 4
234 15608686 hTERT antagonizes p53-induced apoptosis independently of telomerase activity. 2005 Feb 17 1
235 15625077 HMG-CoA reductase inhibitors, statins, induce phosphorylation of Mdm2 and attenuate the p53 response to DNA damage. 2005 Mar 1
236 15691646 Prognostic value of the epidermal growth factor receptor (EGRF) and p53 in advanced head and neck squamous cell carcinoma patients treated with induction chemotherapy. 2005 Feb 1
237 15774934 Adenoviral p53 gene transfer inhibits human Tenon's capsule fibroblast proliferation. 2005 Apr 1
238 15856030 Oncogenic Ras increases sensitivity of colon cancer cells to 5-FU-induced apoptosis. 2005 Jun 2 1
239 15870870 Apoptosis induced by 5-fluorouracil, cisplatin and paclitaxel are associated with p53 gene status in gastric cancer cell lines. 2005 Jun 1
240 15886465 Effects of cisplatin, 5-fluorouracil, and radiation on cell cycle regulation and apoptosis in the hypopharyngeal carcinoma cell line. 2005 May 4
241 16077963 The evaluation of gastric cancer sensitivity to 5-FU/CDDP in terms of induction of apoptosis: time- and p53 expression-dependency of anti-cancer drugs. 2005 Sep 1
242 16168113 Addition of 5-fluorouracil to doxorubicin-paclitaxel sequence increases caspase-dependent apoptosis in breast cancer cell lines. 2005 1
243 16202244 Release of cytochrome c from isolated mitochondria by etoposide. 2005 Sep 30 1
244 16204068 Effect of p53 status and STAT1 on chemotherapy-induced, Fas-mediated apoptosis in colorectal cancer. 2005 Oct 1 2
245 19956517 Thymidylate synthase, thymidine phosphorylase, VEGF and p53 protein expression in primary colorectal cancer for predicting response to 5-fluorouracil-based chemotherapy. 2005 Aug 2
246 12827409 Molecular lesions in colorectal cancer: impact on prognosis? Original data and review of the literature. 2004 Jan 1
247 14665630 Regulation of p53 stability and function in HCT116 colon cancer cells. 2004 Feb 27 4
248 14704126 Wild type p53 increased chemosensitivity of drug-resistant human hepatocellular carcinoma Bel7402/5-FU cells. 2004 Jan 4
249 15010816 Expression of p53 protein as a predictor of the response to 5-fluorouracil and cisplatin chemotherapy in human gastrointestinal cancer cell lines evaluated with apoptosis by use of thin layer collagen gel. 2004 Apr 1
250 15016801 p53-regulated transcriptional program associated with genotoxic stress-induced apoptosis. 2004 May 14 4