Fluorouracil

tumor protein p53 ; Homo sapiens







354 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
101 25736303 Resveratrol synergistically augments anti-tumor effect of 5-FU in vitro and in vivo by increasing S-phase arrest and tumor apoptosis. 2015 Dec 1
102 25965911 PUMA mediates the combinational therapy of 5-FU and NVP-BEZ235 in colon cancer. 2015 Jun 10 1
103 26187504 APR-246 potently inhibits tumour growth and overcomes chemoresistance in preclinical models of oesophageal adenocarcinoma. 2015 Oct 1
104 26188124 A plant alkaloid, veratridine, potentiates cancer chemosensitivity by UBXN2A-dependent inhibition of an oncoprotein, mortalin-2. 2015 Sep 15 1
105 26208523 The 1,2-Diaminocyclohexane Carrier Ligand in Oxaliplatin Induces p53-Dependent Transcriptional Repression of Factors Involved in Thymidylate Biosynthesis. 2015 Oct 1
106 26222289 Multicomponent 5-fluorouracil loaded PAMAM stabilized-silver nanocomposites synergistically induce apoptosis in human cancer cells. 2015 Mar 1
107 26368019 Gypenosides Synergistically Enhances the Anti-Tumor Effect of 5-Fluorouracil on Colorectal Cancer In Vitro and In Vivo: A Role for Oxidative Stress-Mediated DNA Damage and p53 Activation. 2015 3
108 26425688 TP53 Mutational Status and Prediction of Benefit from Adjuvant 5-Fluorouracil in Stage III Colon Cancer Patients. 2015 Aug 3
109 26459801 Targeting the ∆133p53 isoform can restore chemosensitivity in 5-fluorouracil-resistant cholangiocarcinoma cells. 2015 Dec 2
110 24052409 Mahanine synergistically enhances cytotoxicity of 5-fluorouracil through ROS-mediated activation of PTEN and p53/p73 in colon carcinoma. 2014 Jan 1
111 24277474 Thymidylate synthase expression and p21(WAF1)/p53 phenotype of colon cancers identify patients who may benefit from 5-fluorouracil based therapy. 2014 Feb 1
112 24434574 Combination of adenoviruses expressing melanoma differentiation-associated gene-7 and chemotherapeutic agents produces enhanced cytotoxicity on esophageal carcinoma. 2014 Jan 1
113 24462821 Inhibition of p53 increases chemosensitivity to 5-FU in nutrient-deprived hepatocarcinoma cells by suppressing autophagy. 2014 May 1 4
114 24504010 Alteration of gene expression and DNA methylation in drug-resistant gastric cancer. 2014 Apr 1
115 24587255 A compensatory role of NF-κB to p53 in response to 5-FU-based chemotherapy for gastric cancer cell lines. 2014 6
116 24634414 Metallothionein 1G and zinc sensitize human colorectal cancer cells to chemotherapy. 2014 May 2
117 24712391 Combinational delivery of hydrophobic and hydrophilic anticancer drugs in single nanoemulsions to treat MDR in cancer. 2014 Aug 4 1
118 24733045 JNK confers 5-fluorouracil resistance in p53-deficient and mutant p53-expressing colon cancer cells by inducing survival autophagy. 2014 Apr 15 6
119 24801380 Doxorubicin and 5-fluorouracil induced accumulation and transcriptional activity of p53 are independent of the phosphorylation at serine 15 in MCF-7 breast cancer cells. 2014 Aug 1
120 24846461 Silencing of Dicer1 temporally separates pro- and anti-apoptotic signaling and confers susceptibility to chemotherapy in p53 mutated cells. 2014 1
121 25135238 The biomarker TP53 divides patients with neoadjuvantly treated esophageal cancer into 2 subgroups with markedly different outcomes. A p53 Research Group study. 2014 Nov 1
122 25401416 Cooperative interactions between p53 and NFκB enhance cell plasticity. 2014 Dec 15 1
123 25788859 Myricetin enhance chemosensitivity of 5-fluorouracil on esophageal carcinoma in vitro and in vivo. 2014 1
124 22841540 Ursolic acid induces cell death and modulates autophagy through JNK pathway in apoptosis-resistant colorectal cancer cells. 2013 Apr 2
125 22963136 Possible predictive value of maspin expression in colorectal cancer. 2013 May 2
126 23076534 Upregulation of periostin prevents P53-mediated apoptosis in SGC-7901 gastric cancer cells. 2013 Feb 2
127 23108402 5-Fluorouracil signaling through a calcium-calmodulin-dependent pathway is required for p53 activation and apoptosis in colon carcinoma cells. 2013 Sep 19 4
128 23423487 Effect of TP53 codon 72 and MDM2 SNP309 polymorphisms on survival of gastric cancer among patients who receiving 5-fluorouracil-based postoperative adjuvant chemotherapy. 2013 Apr 4
129 23441616 Nobiletin induces apoptosis and potentiates the effects of the anticancer drug 5-fluorouracil in p53-mutated SNU-16 human gastric cancer cells. 2013 3
130 23456958 The unfolded protein response regulator GRP78 is a novel predictive biomarker in colorectal cancer. 2013 Sep 15 1
131 23727578 Identification of human guanylate-binding protein 1 gene (hGBP1) as a direct transcriptional target gene of p53. 2013 Jun 28 4
132 23729362 Inhibition of GSK3B bypass drug resistance of p53-null colon carcinomas by enabling necroptosis in response to chemotherapy. 2013 Jul 15 2
133 23810214 A study of the combination of triamcinolone and 5-fluorouracil in modulating keloid fibroblasts in vitro. 2013 Sep 1
134 23837948 Selenocystine potentiates cancer cell apoptosis induced by 5-fluorouracil by triggering reactive oxygen species-mediated DNA damage and inactivation of the ERK pathway. 2013 Dec 1
135 23936455 TP53 and let-7a micro-RNA regulate K-Ras activity in HCT116 colorectal cancer cells. 2013 1
136 21706156 MDM2 SNP309 and TP53 R72P associated with severe and febrile neutropenia in breast cancer patients treated with 5-FU/epirubicin/cyclophosphamide. 2012 Apr 2
137 21713761 FBI-1 promotes cell proliferation and enhances resistance to chemotherapy of hepatocellular carcinoma in vitro and in vivo. 2012 Jan 1 1
138 22192357 14-3-3σ regulation by p53 mediates a chemotherapy response to 5-fluorouracil in MCF-7 breast cancer cells via Akt inactivation. 2012 Jan 20 2
139 22213289 Dual-mode interaction between quercetin and DNA-damaging drugs in cancer cells. 2012 Jan 1
140 22286760 Poly(ADP-ribosyl)ation of p53 induces gene-specific transcriptional repression of MTA1. 2012 Dec 6 7
141 22441128 Synergistic anticancer effect of rAd/P53 combined with 5-fluorouracil or iodized oil in the early therapeutic response of human colon cancer in vivo. 2012 May 15 10
142 22445862 Docetaxel and 5-fluorouracil induce human p53 tumor suppressor gene transcription via a short sequence at core promoter element. 2012 Aug 3
143 22525470 Different responses to 5-fluoraouracil in mutagenicity and gene expression between two human lymphoblastoid cell lines with or without TP53 mutation. 2012 2
144 22607196 Oroxylin A improves the sensitivity of HT-29 human colon cancer cells to 5-FU through modulation of the COX-2 signaling pathway. 2012 Aug 1
145 22684338 Prospective impact of 5-FU in the induction of endoplasmic reticulum stress, modulation of GRP78 expression and autophagy in Sk-Hep1 cells. 2012 Sep 1
146 22716215 Chloroquine enhances the chemotherapeutic activity of 5-fluorouracil in a colon cancer cell line via cell cycle alteration. 2012 Jul 1
147 22790872 Insights into p53 transcriptional function via genome-wide chromatin occupancy and gene expression analysis. 2012 Dec 5
148 22983008 The transcription factor CREBZF is a novel positive regulator of p53. 2012 Oct 15 1
149 23235459 PRAP1 is a novel executor of p53-dependent mechanisms in cell survival after DNA damage. 2012 Dec 13 3
150 20425122 Thymidylate synthase inhibition induces p53-dependent and p53-independent apoptotic responses in human urinary bladder cancer cells. 2011 Feb 6