Cisplatin

tumor protein p53 ; Homo sapiens







886 Article(s)
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851 9536982 [Relationships between p53 induction, cell cycle arrest and survival of normal human fibroblasts following DNA damage]. 1997 Nov 1
852 9563008 Sensitization of cis-platinum by a recombinant adenovirus vector expressing wild-type p53 gene in human ovarian carcinomas. 1997 3
853 9815601 UCN-01 in ovary cancer cells: effective as a single agent and in combination with cis-diamminedichloroplatinum(II)independent of p53 status. 1997 Nov 3
854 9815771 Apoptosis as a determinant of tumor sensitivity to topotecan in human ovarian tumors: preclinical in vitro/in vivo studies. 1997 Jun 2
855 21590120 Enhancement of apoptosis in irradiated glioblastoma cells by pentoxifylline. 1997 Jul-Aug 1
856 8564971 Association between cisplatin resistance and mutation of p53 gene and reduced bax expression in ovarian carcinoma cell systems. 1996 Feb 1 4
857 8616869 The prognostic significance of Bcl-2 and p53 expression in ovarian carcinoma. 1996 May 1 3
858 8630996 A comparative study of p53 gene mutations, protein accumulation, and response to cisplatin-based chemotherapy in advanced ovarian carcinoma. 1996 Feb 15 4
859 8631030 Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents. 1996 Feb 15 2
860 8653690 Modulation of p53 expression by human recombinant interferon-alpha2a correlates with abrogation of cisplatin resistance in a human melanoma cell line. 1996 Jun 1 3
861 8667426 UCN-01: a potent abrogator of G2 checkpoint function in cancer cells with disrupted p53. 1996 Jul 17 1
862 8687228 [Therapeutic effect of adenovirus-mediated transfer of the wild-type p53 gene with cisplatin]. 1996 Jul 1
863 8760308 Induction of p53 and increased sensitivity to cisplatin in ataxia-telangiectasia cells. 1996 Aug 1 2
864 8808702 WAF1/CIP1 increases the susceptibility of p53 non-functional malignant glioma cells to cisplatin-induced apoptosis. 1996 Sep 19 5
865 8895543 Cisplatin-induced apoptosis and p53 gene status in a cisplatin-resistant human ovarian carcinoma cell line. 1996 Sep 27 2
866 8903408 Tissue-specific growth suppression and chemosensitivity promotion in human hepatocellular carcinoma cells by retroviral-mediated transfer of the wild-type p53 gene. 1996 Nov 1
867 8911337 Gene therapy for lung cancer: enhancement of tumor suppression by a combination of sequential systemic cisplatin and adenovirus-mediated p53 gene transfer. 1996 Nov 8
868 8920796 Expression of p53 and apoptosis of tumor cells in locally advanced cervical carcinoma after cisplatin based neoadjuvant chemotherapy. 1996 Sep-Oct 5
869 8945622 Abrogation of apoptosis induced by DNA-damaging agents in human bladder-cancer cell lines with p21/WAF1/CIP1 and/or p53 gene alterations. 1996 Nov 15 2
870 8950204 High-risk HPV-positive human cancer cell lines show different sensitivity to cisplatin-induced apoptosis correlated with the p21Waf1/Cip1 level. 1996 Nov 12 2
871 8967975 Cisplatin, camptothecin, and taxol sensitivities of cells with p53-associated multidrug resistance. 1996 Dec 2
872 8968086 p53-null cells are more sensitive to ultraviolet light only in the presence of caffeine. 1996 Dec 1 1
873 9042268 The dual role of mutant p53 protein in chemosensitivity of human cancers. 1996 Nov-Dec 1
874 9081399 Ovarian cancer, from the laboratory to the clinic: challenges for the future. 1996 Jan 1
875 7478541 The control of apoptosis and drug resistance in ovarian cancer: influence of p53 and Bcl-2. 1995 Oct 5 1
876 7585548 Aberrant p53 expression predicts clinical resistance to cisplatin-based chemotherapy in locally advanced non-small cell lung cancer. 1995 Nov 1 5
877 7588628 DNA damage in human B cells can induce apoptosis, proceeding from G1/S when p53 is transactivation competent and G2/M when it is transactivation defective. 1995 Oct 16 1
878 7712469 Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline. 1995 Apr 15 8
879 7729416 Epstein-Barr virus efficiently immortalizes human B cells without neutralizing the function of p53. 1995 Apr 3 1
880 7761100 MDM2 protein confers the resistance of a human glioblastoma cell line to cisplatin-induced apoptosis. 1995 May 18 2
881 8519417 Use of wild-type p53 to achieve complete treatment sensitization of tumor cells expressing endogenous mutant p53. 1995 Dec 3
882 8521409 Interleukin-1 beta-converting enzyme mediates cisplatin-induced apoptosis in malignant glioma cells. 1995 Dec 15 2
883 7954409 p53 gene mutations are associated with decreased sensitivity of human lymphoma cells to DNA damaging agents. 1994 Nov 15 2
884 8406999 Increased accumulation of p53 protein in cisplatin-resistant ovarian cell lines. 1993 Oct 21 11
885 8485705 Increases in sequence specific DNA binding by p53 following treatment with chemotherapeutic and DNA damaging agents. 1993 May 15 1
886 21573382 P53 expression in end-stage squamous-cell carcinoma of the head and neck prior to chemotherapy treatment - expression correlates with a very poor clinical outcome. 1993 Sep 1