Iron

tumor protein p53 ; Homo sapiens







70 Article(s)
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51 17349663 Blood mononucleocytes are sensitive to the DNA damaging effects of iron overload--in vitro and ex vivo results with human and rat cells. 2007 Jun 1 1
52 17593032 Hepcidin, a key regulator of iron metabolism, is transcriptionally activated by p53. 2007 Jul 2
53 17822515 Pathogenesis of haemophilic synovitis: experimental studies on blood-induced joint damage. 2007 Nov 1
54 16957011 Apoptotic stress pathway activation mediated by iron on endothelial cells in vitro. 2006 Nov 3
55 17257079 Uptake of anti-anemic substance ferric-sorbitol-citrate by normal and malignant cells and its effects on expression of transferrin receptor 1 and ferritin. 2006 Dec 1
56 16054986 Alcohol, iron-associated oxidative stress, and cancer. 2005 Apr 1
57 15135642 Mutational biases associated with potential iron-binding DNA motifs in rodent lacI and human p53 mutational databases. 2004 Jun 4 1
58 12869419 The effect of potent iron chelators on the regulation of p53: examination of the expression, localization and DNA-binding activity of p53 and the transactivation of WAF1. 2003 Oct 3
59 12387362 Abeta[25-35] peptide and iron promote apoptosis in lymphocytes by an oxidative stress mechanism: involvement of H2O2, caspase-3, NF-kappaB, p53 and c-Jun. 2002 Sep 1
60 12416732 Iron toxicity and chelation therapy. 2002 Oct 1
61 11208917 Site of injury-directed induction of heme oxygenase-1 and -2 in experimental spinal cord injury: differential functions in neuronal defense mechanisms? 2001 Jan 1
62 11448240 Genotoxic effects of high-energy iron particles in human lymphoblasts differing in radiation sensitivity. 2001 Aug 1
63 11576999 p53-independent apoptosis mediated by tachpyridine, an anti-cancer iron chelator. 2001 Oct 1
64 11642302 Cellular responses by exposure to heavy-ions. 2001 1
65 11698570 Oxidative stress and p53 mutations in the carcinogenesis of iron overload-associated hepatocellular carcinoma. 2001 Nov 7 1
66 10930054 Evidence of enhanced iron excretion during systemic phosphorothioate oligodeoxynucleotide treatment. 2000 1
67 11050162 Increased p53 mutation load in nontumorous human liver of wilson disease and hemochromatosis: oxyradical overload diseases. 2000 Nov 7 1
68 9576849 Molecular analysis of H2O2-induced senescent-like growth arrest in normal human fibroblasts: p53 and Rb control G1 arrest but not cell replication. 1998 May 15 1
69 9865721 Up-regulation of hypoxia-inducible factor-1alpha is not sufficient for hypoxic/anoxic p53 induction. 1998 Dec 15 1
70 8590632 Iron deprivation results in an increase in p53 expression. 1995 Oct 2