Doxorubicin

tumor protein p53 ; Homo sapiens







715 Article(s)
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101 29779937 Estrogen receptor positive breast tumors resist chemotherapy by the overexpression of P53 in Cancer Stem Cells. 2018 Jun 1
102 29980405 Introduction of WT-TP53 into pancreatic cancer cells alters sensitivity to chemotherapeutic drugs, targeted therapeutics and nutraceuticals. 2018 Aug 1
103 30103170 Metronomic oral doxorubicin in combination of Chk1 inhibitor MK-8776 for p53-deficient breast cancer treatment. 2018 Nov 5
104 30124118 TP53-dependence on the effect of doxorubicin and Src inhibitor combination therapy. 2018 Aug 5
105 30198376 P53 enhances apoptosis induced by doxorubicin only under conditions of severe DNA damage. 2018 4
106 30217455 4-Hydroxybenzoic acid (4-HBA) enhances the sensitivity of human breast cancer cells to adriamycin as a specific HDAC6 inhibitor by promoting HIPK2/p53 pathway. 2018 Oct 12 2
107 30245854 KLLN-mediated DNA damage-induced apoptosis is associated with regulation of p53 phosphorylation and acetylation in breast cancer cells. 2018 2
108 30257423 Protective Roles of Thymoquinone Nanoformulations: Potential Nanonutraceuticals in Human Diseases. 2018 Sep 25 1
109 30274043 In vitro evaluation of a biomaterial-based anticancer drug delivery system as an alternative to conventional post-surgery bone cancer treatment. 2018 Dec 1 1
110 30285883 Breast cancer survival predicted by TP53 mutation status differs markedly depending on treatment. 2018 Oct 1 1
111 30387987 In Situ Proapoptotic Peptide-Generating Rapeseed Protein-Based Nanocomplexes Synergize Chemotherapy for Cathepsin-B Overexpressing Breast Cancer. 2018 Dec 5 1
112 30405800 Low dose dinaciclib enhances doxorubicin-induced senescence in myeloma RPMI8226 cells by transformation of the p21 and p16 pathways. 2018 Nov 2
113 30488759 Mathematical model identifies effective P53 accumulation with target gene binding affinity in DNA damage response for cell fate decision. 2018 3
114 30507074 Comparative transcriptomic analysis reveals adriamycin-induced apoptosis via p53 signaling pathway in retinal pigment epithelial cells. 2018 Dec. 1
115 32254384 A synergistic polyphosphoester-based co-delivery system of the anticancer drug doxorubicin and the tumor suppressor gene p53 for lung cancer therapy. 2018 May 28 3
116 27617579 FKBP12 enhances sensitivity to chemotherapy-induced cancer cell apoptosis by inhibiting MDM2. 2017 Mar 23 2
117 27770912 Biocompatible cationic pullulan-g-desoxycholic acid-g-PEI micelles used to co-deliver drug and gene for cancer therapy. 2017 Jan 1 2
118 27834950 The novel p53 target TNFAIP8 variant 2 is increased in cancer and offsets p53-dependent tumor suppression. 2017 Jan 2
119 27836734 Doxorubicin anti-tumor mechanisms include Hsp60 post-translational modifications leading to the Hsp60/p53 complex dissociation and instauration of replicative senescence. 2017 Jan 28 1
120 27866093 NSCA-1-a novel N-substituted coumalamide derivative-increases Adriamycin sensitivity in HepG2/adriamycin cells through modulating Akt/GSK-3β signaling and p53-dependant apoptotic pathway. 2017 Jan 2
121 27888811 The role of p53 in cancer drug resistance and targeted chemotherapy. 2017 Jan 31 1
122 28052008 Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin. 2017 Jan 31 1
123 28152424 EPSIN 3, A Novel p53 Target, Regulates the Apoptotic Pathway and Gastric Carcinogenesis. 2017 Mar 3
124 28163043 p53 Modulates the Fate of Cardiac Progenitor Cells Ex Vivo and in the Diabetic Heart In Vivo. 2017 Feb 1
125 28191463 Substrate Stiffness Influences Doxorubicin-Induced p53 Activation via ROCK2 Expression. 2017 4
126 28229963 Constitutively activated ERK sensitizes cancer cells to doxorubicin: Involvement of p53-EGFR-ERK pathway. 2017 Mar 1
127 28232385 The Cytidine Deaminase APOBEC3 Family Is Subject to Transcriptional Regulation by p53. 2017 Jun 1
128 28264987 Nuclear retention of the lncRNA SNHG1 by doxorubicin attenuates hnRNPC-p53 protein interactions. 2017 Apr 7
129 28423695 NDRG2 promotes adriamycin sensitivity through a Bad/p53 complex at the mitochondria in breast cancer. 2017 Apr 25 1
130 28450532 P53-miR-191-SOX4 regulatory loop affects apoptosis in breast cancer. 2017 Aug 2
131 28476801 Azacytidine-induced Chemosensitivity to Doxorubicin in Human Breast Cancer MCF7 Cells. 2017 May 2
132 28498637 β2-AR activation induces chemoresistance by modulating p53 acetylation through upregulating Sirt1 in cervical cancer cells. 2017 Jul 3
133 28528452 Tumor suppressor protein p53 exerts negative transcriptional regulation on human sodium iodide symporter gene expression in breast cancer. 2017 Aug 1
134 28580174 Effects of concomitant inactivation of p53 and pRb on response to doxorubicin treatment in breast cancer cell lines. 2017 5
135 28608259 JS-K, a GST-activated nitric oxide donor prodrug, enhances chemo-sensitivity in renal carcinoma cells and prevents cardiac myocytes toxicity induced by Doxorubicin. 2017 Aug 5
136 28628491 Calcein-acetoxymethy ester enhances the antitumor effects of doxorubicin in nonsmall cell lung cancer by regulating the TopBP1/p53RR pathway. 2017 Sep 4
137 28653879 TP53 alteration determines the combinational cytotoxic effect of doxorubicin and an antioxidant NAC. 2017 Jun 9
138 28655792 Inhibiting p53 Acetylation Reduces Cancer Chemotoxicity. 2017 Aug 15 1
139 28656004 Berberine Reverses Hypoxia-induced Chemoresistance in Breast Cancer through the Inhibition of AMPK- HIF-1α. 2017 1
140 28658321 Effect of the p53-tristetraprolin-stathmin-1 pathway on trophoblasts at maternal-fetal interface. 2017 1
141 28677808 A novel engineered interferon-α hybrid molecule increases anticancer efficacy of doxorubicin in breast cancer chemotherapy. 2017 Sep 1
142 28684738 Mechanistic clues to the protective effect of chrysin against doxorubicin-induced cardiomyopathy: Plausible roles of p53, MAPK and AKT pathways. 2017 Jul 6 1
143 28714518 Regulation of tubular recycling endosome biogenesis by the p53-MICALL1 pathway. 2017 Aug 3
144 28760703 Berberine-induced cardioprotection and Sirt3 modulation in doxorubicin-treated H9c2 cardiomyoblasts. 2017 Nov 1
145 28791403 Complex analysis of the TP53 tumor suppressor in mantle cell and diffuse large B-cell lymphomas. 2017 Oct 1
146 28837147 Doxorubicin upregulates CXCR4 via miR-200c/ZEB1-dependent mechanism in human cardiac mesenchymal progenitor cells. 2017 Aug 24 1
147 28915555 Identification of a p53-repressed gene module in breast cancer cells. 2017 Aug 22 1
148 28937626 Aspalathin Reverts Doxorubicin-Induced Cardiotoxicity through Increased Autophagy and Decreased Expression of p53/mTOR/p62 Signaling. 2017 Sep 22 2
149 28945070 Inhibition of Thioredoxin Reductase by Targeted Selenopolymeric Nanocarriers Synergizes the Therapeutic Efficacy of Doxorubicin in MCF7 Human Breast Cancer Cells. 2017 Oct 25 1
150 29021323 Pathologic Stimulus Determines Lineage Commitment of Cardiac C-kit+ Cells. 2017 Dec 12 2