Hydrogen Peroxide

tumor protein p53 ; Homo sapiens







195 Article(s)
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151 15163458 Transition metal-induced apoptosis in lymphocytes via hydroxyl radical generation, mitochondria dysfunction, and caspase-3 activation: an in vitro model for neurodegeneration. 2004 May-Jun 1
152 15260130 Molecular basis of anti-apoptotic effect of immunophilin ligands on hydrogen peroxide-induced apoptosis in human glioma cells. 2004 Aug 1
153 15489061 Gene expression and regulation in H2O2-induced premature senescence of human foreskin fibroblasts expressing or not telomerase. 2004 Sep 2
154 15573749 [Sensitivity comparison of DNA damage and repair capacity in TK6 and WTK1 cells]. 2004 Nov 2
155 12468545 Catalase protects HepG2 cells from apoptosis induced by DNA-damaging agents by accelerating the degradation of p53. 2003 Feb 14 1
156 12768477 Synergistic induction of apoptosis of rheumatoid arthritis synovial cells by H(2)O(2) and N-acetyl-leucyl-leucyl-norleucinal. 2003 1
157 12805649 Oxidative DNA damage and repair in a cell lineage model of human proliferative breast disease (PBD). 2003 Sep 1
158 12890678 Activation of p53 by oxidative stress involves platelet-derived growth factor-beta receptor-mediated ataxia telangiectasia mutated (ATM) kinase activation. 2003 Oct 10 4
159 12935767 Mechanisms of pyruvate inhibition of oxidant-induced apoptosis in human endothelial cells. 2003 Sep 2
160 12939400 Potential role of MLH1 in the induction of p53 and apoptosis by blocking transcription on damaged DNA templates. 2003 Aug 1
161 12962703 Hydroxylamine potentiates the effect of low dose hydrogen peroxide in glioma cells independent of p53. 2003 Dec 6
162 14637145 Hydrogen peroxide increases a 55-kDa tyrosinase concomitantly with induction of p53-dependent p21 waf1 expression and a greater Bax/Bcl-2 ratio in pigmented melanoma. 2003 Dec 12 2
163 11809417 p53 dependent apoptosis in glioma cell lines in response to hydrogen peroxide induced oxidative stress. 2002 Feb 2
164 11880544 p53 regulation of DNA excision repair pathways. 2002 Mar 1
165 12160929 Possible involvement of glutathione and p53 in trichloroethylene- and perchloroethylene-induced lipid peroxidation and apoptosis in human lung cancer cells. 2002 Aug 15 2
166 12213802 Ceramide and reactive oxygen species generated by H2O2 induce caspase-3-independent degradation of Akt/protein kinase B. 2002 Nov 8 1
167 12397013 Hydrogen peroxide induces upregulation of Fas in human airway epithelial cells via the activation of PARP-p53 pathway. 2002 Nov 3
168 12435813 Overexpression of protein kinase Czeta confers protection against antileukemic drugs by inhibiting the redox-dependent sphingomyelinase activation. 2002 Dec 1
169 11313880 p53 regulates ceramide formation by neutral sphingomyelinase through reactive oxygen species in human glioma cells. 2001 Mar 15 2
170 11447225 Reactive oxygen species-induced phosphorylation of p53 on serine 20 is mediated in part by polo-like kinase-3. 2001 Sep 28 3
171 11673079 The detection of mutations induced in vitro in the human p53 gene by hydrogen peroxide with the restriction site mutation (RSM) assay. 2001 Nov 15 2
172 11744405 Thioredoxin reductase - its role in epidermal redox status. 2001 Nov 15 1
173 10749685 Apoptosis or senescence-like growth arrest: influence of cell-cycle position, p53, p21 and bax in H2O2 response of normal human fibroblasts. 2000 Apr 15 1
174 10893182 Membrane gamma-glutamyl transpeptidase activity of melanoma cells: effects on cellular H(2)O(2) production, cell surface protein thiol oxidation and NF-kappa B activation status. 2000 Aug 1
175 10911952 Replicative senescence and oxidant-induced premature senescence. Beyond the control of cell cycle checkpoints. 2000 Jun 1
176 10922372 Vanadate induces p53 transactivation through hydrogen peroxide and causes apoptosis. 2000 Oct 20 2
177 10939520 Hydrogen peroxide-induced apoptosis in human hepatoma cells is mediated by CD95(APO-1/Fas) receptor/ligand system and may involve activation of wild-type p53. 2000 Mar 4
178 11020329 Mapping oxidative DNA damage using ligation-mediated polymerase chain reaction technology. 2000 Oct 1
179 11708215 Measurements of hydrogen peroxide induced premature senescence: senescence-associated beta-galactosidase and DNA synthesis index in human diploid fibroblasts with down-regulated p53 or Rb. 2000 1
180 12214088 Oxygen free radical injury is sufficient to cause some Alzheimer-type molecular abnormalities in human CNS neuronal cells. 2000 Nov 1
181 9890630 Hydrogen peroxide-induced apoptosis mediated by p53 protein in glial cells. 1999 Jan 15 3
182 9989825 Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-kappaB. 1999 Jan 21 2
183 10359739 Signaling pathways in reactive oxygen species-induced cardiomyocyte apoptosis. 1999 Jun 8 1
184 10403664 Methyl methanesulfonate and hydrogen peroxide differentially regulate p53 accumulation in hepatoblastoma cells. 1999 Jun 1 3
185 10531375 Cadmium induces conformational modifications of wild-type p53 and suppresses p53 response to DNA damage in cultured cells. 1999 Oct 29 1
186 9535218 Apoptosis caused by oxidized LDL is manganese superoxide dismutase and p53 dependent. 1998 Apr 3
187 9576849 Molecular analysis of H2O2-induced senescent-like growth arrest in normal human fibroblasts: p53 and Rb control G1 arrest but not cell replication. 1998 May 15 6
188 9688948 Resistance of pleural mesothelioma cell lines to apoptosis: relation to expression of Bcl-2 and Bax. 1998 Jul 1
189 9799559 Hypochlorous acid activates the tumor suppressor protein p53 in cultured human skin fibroblasts. 1998 Nov 1 2
190 9092641 Redox state regulates binding of p53 to sequence-specific DNA, but not to non-specific or mismatched DNA. 1997 Mar 15 2
191 9257692 Active oxygen species mediate the solar ultraviolet radiation-dependent increase in the tumour suppressor protein p53 in human skin fibroblasts. 1997 Jul 21 1
192 8798554 Regulation of Src family tyrosine kinase activities in adherent human neutrophils. Evidence that reactive oxygen intermediates produced by adherent neutrophils increase the activity of the p58c-fgr and p53/56lyn tyrosine kinases. 1996 Sep 20 1
193 7790313 Nuclear accumulation of p53 in normal human fibroblasts is induced by various cellular stresses which evoke the heat shock response, independently of the cell cycle. 1995 May 1
194 8036011 Oxy-radical induced mutagenesis of hotspot codons 248 and 249 of the human p53 gene. 1994 Aug 2
195 8485705 Increases in sequence specific DNA binding by p53 following treatment with chemotherapeutic and DNA damaging agents. 1993 May 15 1