Caffeine

tumor protein p53 ; Homo sapiens







73 Article(s)
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51 11835680 Caffeine induces TP53-independent G(1)-phase arrest and apoptosis in human lung tumor cells in a dose-dependent manner. 2002 Feb 2
52 12509296 Polymerase eta and p53 jointly regulate cell survival, apoptosis and Mre11 recombination during S phase checkpoint arrest after UV irradiation. 2002 Jan 22 1
53 11291094 Loss of G2/M arrest correlates with radiosensitization in two human sarcoma cell lines with mutant p53. 2001 Apr 20 1
54 11302731 Cadmium induces phosphorylation of p53 at serine 15 in MCF-7 cells. 2001 Apr 20 1
55 11447225 Reactive oxygen species-induced phosphorylation of p53 on serine 20 is mediated in part by polo-like kinase-3. 2001 Sep 28 1
56 11489880 Caffeine sensitizes human H358 cell line to p53-mediated apoptosis by inducing mitochondrial translocation and conformational change of BAX protein. 2001 Oct 19 2
57 11677656 ATM as a target for novel radiosensitizers. 2001 Oct 1
58 11745415 Caffeine and the G2/M block override: a concept resulting from a misleading cell kinetic delay, independent of functional p53. 2001 Nov 1 3
59 10738085 Variation in sensitizing effect of caffeine in human tumour cell lines after gamma-irradiation. 2000 Mar 2
60 10762633 Structure-activity relationships for G2 checkpoint inhibition by caffeine analogs. 2000 May 1
61 10769661 Sensitization and caffeine potentiation of cisplatin cytotoxicity resulting from introduction of wild-type p53 gene in human osteosarcoma. 2000 Jan-Feb 4
62 10809772 Distinct Chk2 activation pathways are triggered by genistein and DNA-damaging agents in human melanoma cells. 2000 May 19 1
63 10049063 DNA damage-associated cell cycle and cell death control is differentially modulated by caffeine in clones with p53 mutations. 1999 Jan 3
64 10331854 Caffeine-increased radiosensitivity is not dependent on a loss of G2/M arrest or apoptosis in bladder cancer cell lines. 1999 Apr 2
65 10485486 Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine. 1999 Sep 1 1
66 10571245 Comparison of the efficacy of 7-hydroxystaurosporine (UCN-01) and other staurosporine analogs to abrogate cisplatin-induced cell cycle arrest in human breast cancer cell lines. 1999 Dec 1 1
67 9393772 Correspondence re: J. S. DeFrank et al., p53-null cells are more sensitive to ultraviolet light only in the presence of caffeine. Cancer Res., 56: 5365-5368, 1996. 1997 Dec 1 1
68 9815821 Inhibition of radiation-induced G2 delay potentiates cell death by apoptosis and/or the induction of giant cells in colorectal tumor cells with disrupted p53 function. 1997 Aug 3
69 8692199 Chromosome changes caused by alterations of p53 expression. 1996 Jul 5 6
70 8837615 Selective radiosensitization of p53-deficient cells by caffeine-mediated activation of p34cdc2 kinase. 1996 Oct 2
71 8964480 [Induction of hyperdiploidy and chromosome breaks in LIM1215 cells expressing the exogenous mutant p53]. 1996 Aug 1
72 8968086 p53-null cells are more sensitive to ultraviolet light only in the presence of caffeine. 1996 Dec 1 7
73 1933891 Participation of p53 protein in the cellular response to DNA damage. 1991 Dec 1 4