Reactive Oxygen Species

tumor protein p53 ; Homo sapiens







511 Article(s)
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301 23844043 UVB irradiation regulates ERK1/2- and p53-dependent thrombomodulin expression in human keratinocytes. 2013 1
302 23863680 [Reactive oxygen species mediate the injury and deficient hematopoietic supportive capacity of umbilical cord derived mesenchymal stem cells induced by iron overload]. 2013 Mar 26 2
303 23872073 Induction of renal fibrotic genes by TGF-β1 requires EGFR activation, p53 and reactive oxygen species. 2013 Nov 2
304 23966169 Mitochondrial p53 mediates a transcription-independent regulation of cell respiration and interacts with the mitochondrial F₁F0-ATP synthase. 2013 Sep 1 1
305 24005866 Ziyuglycoside II inhibits the growth of human breast carcinoma MDA-MB-435 cells via cell cycle arrest and induction of apoptosis through the mitochondria dependent pathway. 2013 Sep 3 2
306 24090840 Effect of zinc oxide nanomaterials-induced oxidative stress on the p53 pathway. 2013 Dec 4
307 24359630 Acidosis induces reprogramming of cellular metabolism to mitigate oxidative stress. 2013 Dec 23 1
308 24376853 Reactive oxygen species mediate Epstein-Barr virus reactivation by N-methyl-N'-nitro-N-nitrosoguanidine. 2013 2
309 32261335 Functionalized selenium nanoparticles with nephroprotective activity, the important roles of ROS-mediated signaling pathways. 2013 Dec 14 2
310 21766316 Effects of SiO2 nanoparticles on HFL-I activating ROS-mediated apoptosis via p53 pathway. 2012 May 1
311 22019631 Tumor suppressor genes and ROS: complex networks of interactions. 2012 Jan 1 3
312 22074401 Gallium compound GaQ(3) -induced Ca(2+) signalling triggers p53-dependent and -independent apoptosis in cancer cells. 2012 May 3
313 22090360 TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence. 2012 Jan 1 1
314 22093905 Expression of the human tumor suppressor p53 induces cell death in Pichia pastoris. 2012 Feb 1
315 22112863 The HDAC inhibitor depsipeptide transactivates the p53/p21 pathway by inducing DNA damage. 2012 Feb 1 1
316 22117045 Inhibition of the MUC1-C oncoprotein induces multiple myeloma cell death by down-regulating TIGAR expression and depleting NADPH. 2012 Jan 19 1
317 22117613 Redox regulation of p53, redox effectors regulated by p53: a subtle balance. 2012 Jun 1 6
318 22178897 PIG3: a novel link between oxidative stress and DNA damage response in cancer. 2012 Dec 31 1
319 22283740 P53 activation plays a crucial role in silibinin induced ROS generation via PUMA and JNK. 2012 Mar 9
320 22298641 Curcumin inhibits protein phosphatases 2A and 5, leading to activation of mitogen-activated protein kinases and death in tumor cells. 2012 Apr 1
321 22304673 Reactive oxygen species: the achilles' heel of cancer cells? 2012 Jun 1 1
322 22393286 Zinc oxide nanoparticles selectively induce apoptosis in human cancer cells through reactive oxygen species. 2012 1
323 22434045 Down-regulation of Fer induces ROS levels accompanied by ATM and p53 activation in colon carcinoma cells. 2012 Jul 2
324 22446899 Novel multiple apoptotic mechanism of shikonin in human glioma cells. 2012 Sep 1
325 22509835 Quercetin enhancement of arsenic-induced apoptosis via stimulating ROS-dependent p53 protein ubiquitination in human HaCaT keratinocytes. 2012 May 2
326 22513874 LAMTOR1 depletion induces p53-dependent apoptosis via aberrant lysosomal activation. 2012 Apr 19 1
327 22521640 WITHDRAWN: Hexavalent chromium induces premature senescence through reactive oxygen species-mediated p53 pathway in L-02 hepatocytes. 2012 Apr 13 1
328 22537194 Molecular mechanism implicated in Pemetrexed-induced apoptosis in human melanoma cells. 2012 Apr 26 4
329 22559194 Does Nrf2 contribute to p53-mediated control of cell survival and death? 2012 Dec 15 5
330 22570471 Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) activity by small molecule GMX1778 regulates reactive oxygen species (ROS)-mediated cytotoxicity in a p53- and nicotinic acid phosphoribosyltransferase1 (NAPRT1)-dependent manner. 2012 Jun 22 4
331 22576012 Autophagy is induced through the ROS-TP53-DRAM1 pathway in response to mitochondrial protein synthesis inhibition. 2012 Jul 1 7
332 22593641 Role of apoptosis-inducing factor, proline dehydrogenase, and NADPH oxidase in apoptosis and oxidative stress. 2012 Feb 1 1
333 22607092 P53-mediated GSH depletion enhanced the cytotoxicity of NO in silibinin-treated human cervical carcinoma HeLa cells. 2012 Sep 1
334 22614867 Nano-TiO2-induced apoptosis by oxidative stress-mediated DNA damage and activation of p53 in human embryonic kidney cells. 2012 Jun 1
335 22641095 p53/p66Shc-mediated signaling contributes to the progression of non-alcoholic steatohepatitis in humans and mice. 2012 Oct 4
336 22750558 The canonical NF-κB pathway differentially protects normal and human tumor cells from ROS-induced DNA damage. 2012 Nov 1
337 22796259 Mycoepoxydiene, a fungal polyketide inhibits MCF-7 cells through simultaneously targeting p53 and NF-κB pathways. 2012 Oct 1 2
338 22796327 Proline dehydrogenase is essential for proline protection against hydrogen peroxide-induced cell death. 2012 Sep 1 1
339 22886373 Hexavalent chromium induces energy metabolism disturbance and p53-dependent cell cycle arrest via reactive oxygen species in L-02 hepatocytes. 2012 Dec 3
340 22892142 Enhanced antitumor activity of vitamin C via p53 in cancer cells. 2012 Oct 15 2
341 22899716 Mutant p53R273H attenuates the expression of phase 2 detoxifying enzymes and promotes the survival of cells with high levels of reactive oxygen species. 2012 Nov 15 3
342 22951418 Increased nuclear factor-κB and loss of p53 are key mechanisms in Myalgic Encephalomyelitis/chronic fatigue syndrome (ME/CFS). 2012 Nov 1
343 23031740 Li-Fraumeni syndrome with simultaneous osteosarcoma and liver cancer: increased expression of a CD44 variant isoform after chemotherapy. 2012 Oct 2 2
344 23137536 MiR-186, miR-216b, miR-337-3p, and miR-760 cooperatively induce cellular senescence by targeting α subunit of protein kinase CKII in human colorectal cancer cells. 2012 Dec 14 1
345 23177934 Glucose utilization via glycogen phosphorylase sustains proliferation and prevents premature senescence in cancer cells. 2012 Dec 5 2
346 23185017 Mitochondrial localization of TIGAR under hypoxia stimulates HK2 and lowers ROS and cell death. 2012 Dec 11 2
347 23216635 Reactive oxygen species mediate Cr(VI)-induced S phase arrest through p53 in human colon cancer cells. 2012 1
348 23257465 [Reactive oxygen species and bone marrow hematopoietic stem cell senescence]. 2012 Dec 1
349 23705067 Aging mechanisms in bone. 2012 Jul 1 1
350 20548326 Changes in the gene expression profile of gastric cancer cells in response to ibuprofen: a gene pathway analysis. 2011 Dec 1