Reactive Oxygen Species

tumor protein p53 ; Homo sapiens







511 Article(s)
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201 27689798 1800MHz Microwave Induces p53 and p53-Mediated Caspase-3 Activation Leading to Cell Apoptosis In Vitro. 2016 1
202 27698449 Cr(VI) induces premature senescence through ROS-mediated p53 pathway in L-02 hepatocytes. 2016 Oct 4 4
203 27701048 Cobalt iron oxide nanoparticles induce cytotoxicity and regulate the apoptotic genes through ROS in human liver cells (HepG2). 2016 Dec 1 1
204 27774504 Data analyses of honokiol-induced autophagy of human glioma cells in vitro and in vivo. 2016 Dec 1
205 27994465 Polyethylenimine-functionalized silver nanoparticle-based co-delivery of paclitaxel to induce HepG2 cell apoptosis. 2016 1
206 28149884 P53 mutations and cancer: a tight linkage. 2016 Dec 2
207 24469051 Selective killing of lung cancer cells by miRNA-506 molecule through inhibiting NF-κB p65 to evoke reactive oxygen species generation and p53 activation. 2015 Feb 5 2
208 24858040 The uric acid transporter SLC2A9 is a direct target gene of the tumor suppressor p53 contributing to antioxidant defense. 2015 Apr 2 6
209 25252686 p53 as a retrovirus-induced oxidative stress modulator. 2015 Jan 2
210 25333296 Icariside II inhibits cell proliferation and induces cell cycle arrest through the ROS-p38-p53 signaling pathway in A375 human melanoma cells. 2015 Jan 2
211 25404486 Selective ROS-dependent p53-associated anticancer effects of the hypoxoside derivative rooperol on human teratocarcinomal cancer stem-like cells. 2015 Feb 1
212 25464270 CUL4B impedes stress-induced cellular senescence by dampening a p53-reactive oxygen species positive feedback loop. 2015 Feb 6
213 25464291 In depth analysis of apoptosis induced by silica coated manganese oxide nanoparticles in vitro. 2015 2
214 25483068 ATM regulates cell fate choice upon p53 activation by modulating mitochondrial turnover and ROS levels. 2015 1
215 25483438 Hyperglycemia-induced GLP-1R downregulation causes RPE cell apoptosis. 2015 Feb 1
216 25575314 Studies on antitumor mechanism of two planar platinum(II) complexes with 8-hydroxyquinoline: synthesis, characterization, cytotoxicity, cell cycle and apoptosis. 2015 Mar 6 1
217 25583481 Inhibition of oxidative metabolism leads to p53 genetic inactivation and transformation in neural stem cells. 2015 Jan 27 1
218 25658320 Calpain-3 impairs cell proliferation and stimulates oxidative stress-mediated cell death in melanoma cells. 2015 1
219 25766317 Reactive oxygen species and p21Waf1/Cip1 are both essential for p53-mediated senescence of head and neck cancer cells. 2015 Mar 12 9
220 25799988 Ferroptosis as a p53-mediated activity during tumour suppression. 2015 Apr 2 3
221 25814188 A tryptophanol-derived oxazolopiperidone lactam is cytotoxic against tumors via inhibition of p53 interaction with murine double minute proteins. 2015 May-Jun 1
222 25839657 Endogenous ROS levels are increased in replicative senescence in human bone marrow mesenchymal stromal cells. 2015 May 15 2
223 25947292 PLGA-Loaded Gold-Nanoparticles Precipitated with Quercetin Downregulate HDAC-Akt Activities Controlling Proliferation and Activate p53-ROS Crosstalk to Induce Apoptosis in Hepatocarcinoma Cells. 2015 Jun 2
224 26024660 ROS-p53-cyclophilin-D signaling mediates salinomycin-induced glioma cell necrosis. 2015 May 30 5
225 26049746 The importance of hypoxia and extra physiologic oxygen shock/stress for collection and processing of stem and progenitor cells to understand true physiology/pathology of these cells ex vivo. 2015 Jul 1
226 26051007 Proteomic Analysis of G2/M Arrest Triggered by Natural Borneol/Curcumin in HepG2 Cells, the Importance of the Reactive Oxygen Species-p53 Pathway. 2015 Jul 22 1
227 26105784 Heat stress induced apoptosis is triggered by transcription-independent p53, Ca(2+) dyshomeostasis and the subsequent Bax mitochondrial translocation. 2015 Jun 24 1
228 26114728 RNA sequencing supports distinct reactive oxygen species-mediated pathways of apoptosis by high and low size mass fractions of Bay leaf (Lauris nobilis) in HT-29 cells. 2015 Aug 1
229 26122615 p53 in survival, death and metabolic health: a lifeguard with a licence to kill. 2015 Jul 1
230 26123305 Two for the Price of One: G Protein-Dependent and -Independent Functions of RGS6 In Vivo. 2015 1
231 26133772 PIG3 plays an oncogenic role in papillary thyroid cancer by activating the PI3K/AKT/PTEN pathway. 2015 Sep 6
232 26148435 Arsenic-induced S phase cell cycle lengthening is associated with ROS generation, p53 signaling and CDC25A expression. 2015 Aug 5 3
233 26162681 Potent organo-osmium compound shifts metabolism in epithelial ovarian cancer cells. 2015 Jul 21 2
234 26218928 Dynamic roles of p53-mediated metabolic activities in ROS-induced stress responses. 2015 5
235 26259609 Etoposide Induces Necrosis Through p53-Mediated Antiapoptosis in Human Kidney Proximal Tubule Cells. 2015 Nov 1
236 26264138 Overexpression of yeast thioredoxin TRX2 reduces p53-mediated cell death in yeast. 2015 Oct 5
237 26363031 Mutagenic, surviving and tumorigenic effects of follicular fluid in the context of p53 loss: initiation of fimbria carcinogenesis. 2015 Nov 2
238 26408691 Zinc Induces Apoptosis of Human Melanoma Cells, Increasing Reactive Oxygen Species, p53 and FAS Ligand. 2015 Oct 1
239 26459859 Unconjugated Bilirubin exerts Pro-Apoptotic Effect on Platelets via p38-MAPK activation. 2015 Oct 13 1
240 26472020 Role of miR-182 in response to oxidative stress in the cell fate of human fallopian tube epithelial cells. 2015 Nov 17 1
241 26535076 Pretreatment with Lycopene Attenuates Oxidative Stress-Induced Apoptosis in Human Mesenchymal Stem Cells. 2015 Nov 1
242 32262124 Rational design and fabrication of a cancer-targeted chitosan nanocarrier to enhance selective cellular uptake and anticancer efficacy of selenocystine. 2015 Mar 28 2
243 24052409 Mahanine synergistically enhances cytotoxicity of 5-fluorouracil through ROS-mediated activation of PTEN and p53/p73 in colon carcinoma. 2014 Jan 3
244 24063548 PTEN phosphorylation and nuclear export mediate free fatty acid-induced oxidative stress. 2014 Mar 20 2
245 24356923 A cascade leading to premature aging phenotypes including abnormal tumor profiles in Werner syndrome (review). 2014 Feb 2
246 24361399 Premature senescence in human breast cancer and colon cancer cells by tamoxifen-mediated reactive oxygen species generation. 2014 Mar 3 1
247 24381013 Understanding the non-canonical pathways involved in p53-mediated tumor suppression. 2014 Apr 1
248 24413150 ROS-dependent activation of JNK converts p53 into an efficient inhibitor of oncogenes leading to robust apoptosis. 2014 Apr 5
249 24418562 Reactive oxygen species activate NFκB (p65) and p53 and induce apoptosis in RVFV infected liver cells. 2014 Jan 20 2
250 24462821 Inhibition of p53 increases chemosensitivity to 5-FU in nutrient-deprived hepatocarcinoma cells by suppressing autophagy. 2014 May 1 1