Reactive Oxygen Species

tumor protein p53 ; Homo sapiens







511 Article(s)
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151 28673807 Walsuronoid B induces mitochondrial and lysosomal dysfunction leading to apoptotic rather than autophagic cell death via ROS/p53 signaling pathways in liver cancer. 2017 Oct 15 2
152 28691365 Cooperation between p21 and Akt is required for p53-dependent cellular senescence. 2017 Oct 1
153 28749708 SMG-1 kinase attenuates mitochondrial ROS production but not cell respiration deficits during hyperoxia. 2017 Aug - Sep 4
154 28813624 TP53 Mutational Status and ROS Effect the Expression of the Survivin-Associated Radio-Adaptive Response. 2017 Nov 2
155 28835450 The differential role of reactive oxygen species in early and late stages of cancer. 2017 Dec 1 1
156 28888620 The caspase-8/Bid/cytochrome c axis links signals from death receptors to mitochondrial reactive oxygen species production. 2017 Nov 1
157 28927457 p53: key conductor of all anti-acne therapies. 2017 Sep 19 1
158 28931625 PML is a ROS sensor activating p53 upon oxidative stress. 2017 Nov 6 1
159 28944886 Sulforaphane induces p53‑deficient SW480 cell apoptosis via the ROS‑MAPK signaling pathway. 2017 Nov 1
160 28971953 Rapamycin and CHIR99021 Coordinate Robust Cardiomyocyte Differentiation From Human Pluripotent Stem Cells Via Reducing p53-Dependent Apoptosis. 2017 Oct 2 1
161 28981686 The nuclear mitotic apparatus protein NuMA controls rDNA transcription and mediates the nucleolar stress response in a p53-independent manner. 2017 Nov 16 1
162 28989024 Protein kinase C downregulation induces senescence via FoxO3a inhibition in HCT116 and HEK293 cells. 2017 Dec 2 3
163 29033244 iASPP Is an Antioxidative Factor and Drives Cancer Growth and Drug Resistance by Competing with Nrf2 for Keap1 Binding. 2017 Nov 13 1
164 29039537 Juglone potentiates TRAIL‑induced apoptosis in human melanoma cells via activating the ROS‑p38‑p53 pathway. 2017 Dec 1
165 29042481 The matricellular protein TSP1 promotes human and mouse endothelial cell senescence through CD47 and Nox1. 2017 Oct 17 2
166 29051574 Florfenicol-induced Mitochondrial Dysfunction Suppresses Cell Proliferation and Autophagy in Fibroblasts. 2017 Oct 19 1
167 29051813 Differential impact of various reactive oxygen species (ROS) on HIF-1α/p53 direct interaction in SK-N-MC neuroblastoma cells. 2017 5
168 29127423 Tumor suppressor NPRL2 induces ROS production and DNA damage response. 2017 Nov 10 1
169 29233996 PEPD is a pivotal regulator of p53 tumor suppressor. 2017 Dec 12 4
170 26592665 Radiosensitizing effect of PSMC5, a 19S proteasome ATPase, in H460 lung cancer cells. 2016 Jan 1 1
171 26630137 Study of Bioreductive Anticancer Agent RH-1-Induced Signals Leading the Wild-Type p53-Bearing Lung Cancer A549 Cells to Apoptosis. 2016 Jan 19 1
172 26675982 Identification of the TP53-induced glycolysis and apoptosis regulator in various stages of colorectal cancer patients. 2016 Mar 1
173 26691054 Oncogenic role of the TP53-induced glycolysis and apoptosis regulator in nasopharyngeal carcinoma through NF-κB pathway modulation. 2016 Feb 2
174 26727575 Mieap-regulated mitochondrial quality control is frequently inactivated in human colorectal cancer. 2016 Jan 4 2
175 26756900 COX-2 inhibitor NS-398 suppresses doxorubicin-induced p53 accumulation through inhibition of ROS-mediated Jnk activation. 2016 Dec 4
176 26794443 Ferroptosis: process and function. 2016 Mar 2
177 26934645 Proteasomal degradation of sphingosine kinase 1 and inhibition of dihydroceramide desaturase by the sphingosine kinase inhibitors, SKi or ABC294640, induces growth arrest in androgen-independent LNCaP-AI prostate cancer cells. 2016 Mar 29 1
178 26936104 Paeoniflorin attenuates ultraviolet B-induced apoptosis in human keratinocytes by inhibiting the ROS-p38-p53 pathway. 2016 Apr 4
179 26936454 Carnosic acid induces apoptosis through inactivation of Src/STAT3 signaling pathway in human renal carcinoma Caki cells. 2016 May 1
180 26984266 Kaempferol induces ATM/p53-mediated death receptor and mitochondrial apoptosis in human umbilical vein endothelial cells. 2016 May 1
181 27032906 Trichosanthin-induced autophagy in gastric cancer cell MKN-45 is dependent on reactive oxygen species (ROS) and NF-κB/p53 pathway. 2016 Jun 1
182 27102814 Enhancement of anti-tumor effects of 5-fluorouracil on hepatocellular carcinoma by low-intensity ultrasound. 2016 Apr 22 1
183 27148686 Nrf2-driven TERT regulates pentose phosphate pathway in glioblastoma. 2016 May 5 1
184 27229883 β-Ecdysterone Protects SH-SY5Y Cells Against 6-Hydroxydopamine-Induced Apoptosis via Mitochondria-Dependent Mechanism: Involvement of p38(MAPK)-p53 Signaling Pathway. 2016 Oct 1
185 27233942 Designing piperlongumine-directed anticancer agents by an electrophilicity-based prooxidant strategy: A mechanistic investigation. 2016 Aug 1
186 27236003 Honokiol induces autophagic cell death in malignant glioma through reactive oxygen species-mediated regulation of the p53/PI3K/Akt/mTOR signaling pathway. 2016 Aug 1 2
187 27260513 8-Oxo-7,8-dihydro-2'-deoxyguanosine and other lesions along the coding strand of the exon 5 of the tumour suppressor gene P53 in a breast cancer case-control study. 2016 Aug 1
188 27270209 Modulation of oxidative stress and subsequent induction of apoptosis and endoplasmic reticulum stress allows citral to decrease cancer cell proliferation. 2016 Jun 8 1
189 27314071 Ferroptosis: A missing puzzle piece in the p53 blueprint? 2016 May 1
190 27323408 LACE1 interacts with p53 and mediates its mitochondrial translocation and apoptosis. 2016 Jul 26 1
191 27339904 Combined treatment with vitamin C and sulindac synergistically induces p53- and ROS-dependent apoptosis in human colon cancer cells. 2016 Sep 6 2
192 27371670 Regulation of Cellular Metabolism and Hypoxia by p53. 2016 Jul 1 3
193 27399772 Lebein, a Snake Venom Disintegrin, Induces Apoptosis in Human Melanoma Cells. 2016 Jul 5 2
194 27462151 Multifunctional selenium nanoparticles as carriers of HSP70 siRNA to induce apoptosis of HepG2 cells. 2016 1
195 27470586 Inactivation of the FoxO3a transcription factor is associated with the production of reactive oxygen species during protein kinase CK2 downregulation-mediated senescence in human colon cancer and breast cancer cells. 2016 Sep 9 2
196 27496966 Nimbolide sensitizes human colon cancer cells to TRAIL through reactive oxygen species- and ERK-dependent up-regulation of death receptors, p53, and Bax. 2016 Aug 5 1
197 27501149 Minnelide/Triptolide Impairs Mitochondrial Function by Regulating SIRT3 in P53-Dependent Manner in Non-Small Cell Lung Cancer. 2016 2
198 27520561 p53 functional deficiency in human colon cancer cells promotes fibroblast-mediated angiogenesis and tumor growth. 2016 Oct 1
199 27599894 Antioxidant effects of Cirsium setidens extract on oxidative stress in human mesenchymal stem cells. 2016 Oct 1
200 27634759 Posttranscriptional Upregulation of p53 by Reactive Oxygen Species in Chronic Lymphocytic Leukemia. 2016 Nov 1 2