Reactive Oxygen Species

tumor protein p53 ; Homo sapiens







511 Article(s)
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101 29225132 Ginsenoside Rh4 induces apoptosis and autophagic cell death through activation of the ROS/JNK/p53 pathway in colorectal cancer cells. 2018 Feb 1
102 29291545 Impaired pentose phosphate pathway in the development of 3D MCF-7 cells mediated intracellular redox disturbance and multi-cellular resistance without drug induction. 2018 May 2
103 29323455 Selenocysteine inhibits human osteosarcoma cells growth through triggering mitochondrial dysfunction and ROS-mediated p53 phosphorylation. 2018 May 5
104 29402413 Inhibition of CREPT restrains gastric cancer growth by regulation of cycle arrest, migration and apoptosis via ROS-regulated p53 pathway. 2018 Feb 19 1
105 29433671 Phytochemical-induced reactive oxygen species and endoplasmic reticulum stress-mediated apoptosis and differentiation in malignant melanoma cells. 2018 Jan 15 3
106 29466247 Ultraviolet A irradiation induces senescence in human dermal fibroblasts by down-regulating DNMT1 via ZEB1. 2018 Feb 16 1
107 29471006 Astilbin ameliorates cisplatin-induced nephrotoxicity through reducing oxidative stress and inflammation. 2018 Apr 1
108 29483824 Dioscin overcome TKI resistance in EGFR-mutated lung adenocarcinoma cells via down-regulation of tyrosine phosphatase SHP2 expression. 2018 1
109 29511347 PARP-1 inhibition with or without ionizing radiation confers reactive oxygen species-mediated cytotoxicity preferentially to cancer cells with mutant TP53. 2018 May 1
110 29518119 Arylamine N-acetyltransferase 1 protects against reactive oxygen species during glucose starvation: Role in the regulation of p53 stability. 2018 1
111 29568362 The metal-nonoate Ni(SalPipNONO) inhibits in vitro tumor growth, invasiveness and angiogenesis. 2018 Mar 2 2
112 29568929 Effect of KNDC1 overexpression on the senescence of human umbilical vein endothelial cells. 2018 May 1
113 29668110 Phenylbutyl isoselenocyanate induces reactive oxygen species to inhibit androgen receptor and to initiate p53-mediated apoptosis in LNCaP prostate cancer cells. 2018 Aug 2
114 29673545 Curcumin induces apoptosis and cell cycle arrest via the activation of reactive oxygen species-independent mitochondrial apoptotic pathway in Smad4 and p53 mutated colon adenocarcinoma HT29 cells. 2018 Mar 2
115 29698619 Flavan enantiomers from Daphne giraldii selectively induce apoptotic cell death in p53-null hepatocarcinoma cells in vitro. 2018 Jun 1 1
116 29723979 Reactive Oxygen Species, Superoxide Dimutases, and PTEN-p53-AKT-MDM2 Signaling Loop Network in Mesenchymal Stem/Stromal Cells Regulation. 2018 May 1 1
117 29786746 Luteolin induces myelodysplastic syndrome‑derived cell apoptosis via the p53‑dependent mitochondrial signaling pathway mediated by reactive oxygen species. 2018 Aug 3
118 29805774 p53 and metabolism: from mechanism to therapeutics. 2018 May 4 1
119 29843463 Zinc Metallochaperones as Mutant p53 Reactivators: A New Paradigm in Cancer Therapeutics. 2018 May 29 3
120 29916532 Resveratrol induced reactive oxygen species and endoplasmic reticulum stress‑mediated apoptosis, and cell cycle arrest in the A375SM malignant melanoma cell line. 2018 Sep 2
121 29923368 Human electronegative LDL induces mitochondrial dysfunction and premature senescence of vascular cells in vivo. 2018 Aug 2
122 29928326 Miltirone-induced apoptosis in cisplatin-resistant lung cancer cells through upregulation of p53 signaling pathways. 2018 Jun 1
123 29941676 Detection of a novel, primate-specific 'kill switch' tumor suppression mechanism that may fundamentally control cancer risk in humans: an unexpected twist in the basic biology of TP53. 2018 Nov 2
124 29964297 P53 mediates lipopolysaccharide-induced inflammation in human gingival fibroblasts. 2018 Sep 4
125 30003648 Monoamine oxidase-A is a novel driver of stress-induced premature senescence through inhibition of parkin-mediated mitophagy. 2018 Oct 1
126 30283098 NF-κB-related decrease of glioma angiogenic potential by graphite nanoparticles and graphene oxide nanoplatelets. 2018 Oct 3 2
127 30348672 Ex vivo human HSC expansion requires coordination of cellular reprogramming with mitochondrial remodeling and p53 activation. 2018 Oct 23 2
128 30450337 Targeted p53 on Small-Molecules-Induced Ferroptosis in Cancers. 2018 8
129 30483050 PINK1 Protects Against Gentamicin-Induced Sensory Hair Cell Damage: Possible Relation to Induction of Autophagy and Inhibition of p53 Signal Pathway. 2018 2
130 30591679 Stemness, Pluripotentiality, and Wnt Antagonism: sFRP4, a Wnt antagonist Mediates Pluripotency and Stemness in Glioblastoma. 2018 Dec 27 1
131 27238838 Foxp3 is a key downstream regulator of p53-mediated cellular senescence. 2017 Jan 12 1
132 27927016 Inhibition of Cathepsin S Induces Mitochondrial ROS That Sensitizes TRAIL-Mediated Apoptosis Through p53-Mediated Downregulation of Bcl-2 and c-FLIP. 2017 Aug 1 4
133 27976481 Irradiation with UV-C inhibits TNF-α-dependent activation of the NF-κB pathway in a mechanism potentially mediated by reactive oxygen species. 2017 Jan 1
134 28081741 Depletion of NFBD1/MDC1 Induces Apoptosis in Nasopharyngeal Carcinoma Cells Through the p53-ROS-Mitochondrial Pathway. 2017 Jan 2 3
135 28130753 Fluctuation of ROS regulates proliferation and mediates inhibition of migration by reducing the interaction between DLC1 and CAV-1 in breast cancer cells. 2017 Apr 2
136 28131902 CQ synergistically sensitizes human colorectal cancer cells to SN-38/CPT-11 through lysosomal and mitochondrial apoptotic pathway via p53-ROS cross-talk. 2017 Mar 3
137 28150492 Mesoporous Silica Nanoparticles as an Antitumoral-Angiogenesis Strategy. 2017 Mar 1 2
138 28258023 Importance of ROS-mediated autophagy in determining apoptotic cell death induced by physapubescin B. 2017 Aug 1
139 28272690 Licorice and its active compound glycyrrhizic acid ameliorates cisplatin-induced nephrotoxicity through inactivation of p53 by scavenging ROS and overexpression of p21 in human renal proximal tubular epithelial cells. 2017 Feb 4
140 28280421 The oncogenic effects of p53-inducible gene 3 (PIG3) in colon cancer cells. 2017 Mar 4
141 28346428 Autophagy is required for cell survival under L-asparaginase-induced metabolic stress in acute lymphoblastic leukemia cells. 2017 Jul 27 1
142 28356713 Artonin E induces p53-independent G1 cell cycle arrest and apoptosis through ROS-mediated mitochondrial pathway and livin suppression in MCF-7 cells. 2017 1
143 28425621 p53-competent cells and p53-deficient cells display different susceptibility to oxygen functionalized graphene cytotoxicity and genotoxicity. 2017 Nov 1
144 28502718 Mitochondrial ND5 mutation mediated elevated ROS regulates apoptotic pathway epigenetically in a P53 dependent manner for generating pro-cancerous phenotypes. 2017 Jul 3
145 28543759 Abrus agglutinin promotes irreparable DNA damage by triggering ROS generation followed by ATM-p73 mediated apoptosis in oral squamous cell carcinoma. 2017 Nov 1
146 28560439 Isoliquiritigenin inhibits the proliferation of human renal carcinoma Caki cells through the ROS-mediated regulation of the Jak2/STAT3 pathway. 2017 Jul 1
147 28574838 Histone modifications affect differential regulation of TGFβ- induced NADPH oxidase 4 (NOX4) by wild-type and mutant p53. 2017 Jul 4 9
148 28609685 Palmitate induces VSMC apoptosis via toll like receptor (TLR)4/ROS/p53 pathway. 2017 Aug 1
149 28653879 TP53 alteration determines the combinational cytotoxic effect of doxorubicin and an antioxidant NAC. 2017 Jun 3
150 28661480 Role of peroxiredoxin2 downregulation in recurrent miscarriage through regulation of trophoblast proliferation and apoptosis. 2017 Jun 29 2