Lysine

tumor protein p53 ; Homo sapiens







249 Article(s)
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201 14759370 Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation. 2004 Jan 30 3
202 14968111 Modulation of p53 transcription regulatory activity and post-translational modification by hepatitis C virus core protein. 2004 Apr 1 3
203 15302922 Evolution of p53 in hypoxia-stressed Spalax mimics human tumor mutation. 2004 Aug 17 1
204 15364927 Negative regulation of p53 functions by Daxx and the involvement of MDM2. 2004 Nov 26 4
205 15525938 Regulation of p53 activity through lysine methylation. 2004 Nov 18 2
206 12501250 Human immunodeficiency virus type-1 Tat/co-activator acetyltransferase interactions inhibit p53Lys-320 acetylation and p53-responsive transcription. 2003 Apr 4 2
207 12586367 Differences in the ubiquitination of p53 by Mdm2 and the HPV protein E6. 2003 Feb 11 1
208 12716906 The role of p53 deacetylation in p21Waf1 regulation by laminar flow. 2003 Jul 4 4
209 12724314 Identification and characterization of a novel p300-mediated p53 acetylation site, lysine 305. 2003 Jul 11 2
210 12726776 Hyper nuclear acetylation (HNA) in proliferation, differentiation and apoptosis. 2003 Jul 1
211 12750254 p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity. 2003 May 15 2
212 12844488 Association of the DNA repair gene XPD Asp312Asn polymorphism with p53 gene mutations in tobacco-related non-small cell lung cancer. 2003 Oct 1
213 14517211 A defect in the p53 response pathway induced by de novo purine synthesis inhibition. 2003 Dec 5 1
214 14522900 ING1 represses transcription by direct DNA binding and through effects on p53. 2003 Sep 15 1
215 14583461 Loss of p53 has site-specific effects on histone H3 modification, including serine 10 phosphorylation important for maintenance of ploidy. 2003 Oct 15 1
216 14661947 Molecular basis for Gcn5/PCAF histone acetyltransferase selectivity for histone and nonhistone substrates. 2003 Dec 16 2
217 14695212 Induction of PIG3 and NOXA through acetylation of p53 at 320 and 373 lysine residues as a mechanism for apoptotic cell death by histone deacetylase inhibitors. 2003 Dec 15 4
218 11740489 Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2. 2002 Jan 3
219 11875057 ATM mediates phosphorylation at multiple p53 sites, including Ser(46), in response to ionizing radiation. 2002 Apr 12 4
220 11960383 C-terminus of p53 is required for G(2) arrest. 2002 Mar 27 4
221 11971195 Multiple lysine mutations in the C-terminus of p53 make it resistant to degradation mediated by MDM2 but not by human papillomavirus E6 and induce growth inhibition in MDM2-overexpressing cells. 2002 Apr 11 4
222 12019170 Initiation of human astrocytoma by clonal evolution of cells with progressive loss of p53 functions in a patient with a 283H TP53 germ-line mutation: evidence for a precursor lesion. 2002 May 15 3
223 12391296 Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor. 2002 Oct 29 1
224 12421820 Acetylation of p53 inhibits its ubiquitination by Mdm2. 2002 Dec 27 2
225 12426395 MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation. 2002 Nov 15 5
226 11314025 p53 activation in response to microtubule disruption is mediated by integrin-Erk signaling. 2001 Feb 22 1
227 11481424 DNA damage-inducible gene p33ING2 negatively regulates cell proliferation through acetylation of p53. 2001 Aug 14 1
228 11495913 Osmotic shock induces G1 arrest through p53 phosphorylation at Ser33 by activated p38MAPK without phosphorylation at Ser15 and Ser20. 2001 Oct 19 2
229 11713288 Identification of p53 sequence elements that are required for MDM2-mediated nuclear export. 2001 Dec 7
230 10788439 c-Jun and p53 activity is modulated by SUMO-1 modification. 2000 May 5 1
231 10891493 Adenovirus E1B 55-kilodalton oncoprotein inhibits p53 acetylation by PCAF. 2000 Aug 1
232 10910364 PML regulates p53 acetylation and premature senescence induced by oncogenic Ras. 2000 Jul 13 1
233 11046142 Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome-mediated degradation. 2000 Nov 6
234 11094089 Multiple lysine mutations in the C-terminal domain of p53 interfere with MDM2-dependent protein degradation and ubiquitination. 2000 Dec 1
235 9891054 p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage. 1999 Feb 3
236 10207063 Reactivation of mutant p53 through interaction of a C-terminal peptide with the core domain. 1999 May 1
237 10321742 The nuclear import of p53 is determined by the presence of a basic domain and its relative position to the nuclear localization signal. 1999 Mar 25 2
238 10551826 A bipartite nuclear localization signal is required for p53 nuclear import regulated by a carboxyl-terminal domain. 1999 Nov 12 1
239 10562558 Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1. 1999 Nov 15 2
240 10600518 Hypernuclear acetylation in atherosclerotic lesions and activated vascular smooth muscle cells. 1999 Dec 20 1
241 12953991 P53 gene of chang-liver cells (Atcc-Ccl13) exposed to aflatoxin B1 (Afb): the effect of lysine on mutation at codon 249 of exon 7. 1999 Mar-Jun 2
242 9530523 A novel p53 mutation hotspot at codon 132 (AAG-->AGG) in human renal cancer. 1998 Feb 1
243 9677415 Cooperation of a single lysine mutation and a C-terminal domain in the cytoplasmic sequestration of the p53 protein. 1998 Jul 31 5
244 9744860 DNA damage activates p53 through a phosphorylation-acetylation cascade. 1998 Sep 15 3
245 8599213 Sensitivity of p53 lysine mutants to ubiquitin-directed degradation targeted by human papillomavirus E6. 1996 Mar 1 1
246 8649776 The 273rd codon mutants of p53 show growth modulation activities not correlated with p53-specific transactivation activity. 1996 Jun 6 1
247 8275497 The involvement of "tumor suppressor" p53 in normal and chronic myelogenous leukemia hemopoiesis. 1994 Jan 15 1
248 1406679 Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53. 1992 Nov 1
249 1450522 Preference of human cdc2 kinase for peptide substrate. 1992 Sep-Oct 1