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tumor protein p53 ; Homo sapiens







126 Article(s)
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51 27729002 miR-30 functions as an oncomiR in gastric cancer cells through regulation of P53-mediated mitochondrial apoptotic pathway. 2017 Jan 1
52 27913286 Cytotoxic activity of soy phytoestrogen coumestrol against human breast cancer MCF-7 cells: Insights into the molecular mechanism. 2017 Jan 2
53 28109089 Betulinic Acid Inhibits Cell Proliferation in Human Oral Squamous Cell Carcinoma via Modulating ROS-Regulated p53 Signaling. 2017 Aug 7 2
54 28110188 p53 dependent apoptosis and cell cycle delay induced by heteroleptic complexes in human cervical cancer cells. 2017 Apr 1
55 28294157 Alkaline ceramidase 2 is a novel direct target of p53 and induces autophagy and apoptosis through ROS generation. 2017 Mar 15 1
56 28571773 DATS sensitizes glioma cells to TRAIL-mediated apoptosis by up-regulation of death receptor 5 via ROS. 2017 Aug 1
57 28796811 Biphasic ROS production, p53 and BIK dictate the mode of cell death in response to DNA damage in colon cancer cells. 2017 1
58 28831795 Covalent Organic Framework Material Bearing Phloroglucinol Building Units as a Potent Anticancer Agent. 2017 Sep 20 1
59 28912678 IL-17A Enhances Microglial Response to OGD by Regulating p53 and PI3K/Akt Pathways with Involvement of ROS/HMGB1. 2017 2
60 28942112 Synthesis, structure-activity relationships and preliminary mechanism of action of novel water-soluble 4-quinolone-3-carboxamides as antiproliferative agents. 2017 Nov 10 1
61 29179721 Apigenin, by activating p53 and inhibiting STAT3, modulates the balance between pro-apoptotic and pro-survival pathways to induce PEL cell death. 2017 Nov 28 1
62 26152521 Carnosic acid inhibits STAT3 signaling and induces apoptosis through generation of ROS in human colon cancer HCT116 cells. 2016 Jun 1
63 26507802 Aquation Is a Crucial Activation Step for Anticancer Action of Ruthenium(II) Polypyridyl Complexes to Trigger Cancer Cell Apoptosis. 2016 Jan 1
64 26775629 Imiquimod activates p53-dependent apoptosis in a human basal cell carcinoma cell line. 2016 Mar 2
65 26884717 Cyclosporine A Suppressed Glucose Oxidase Induced P53 Mitochondrial Translocation and Hepatic Cell Apoptosis through Blocking Mitochondrial Permeability Transition. 2016 1
66 26942697 Repeated PM2.5 exposure inhibits BEAS-2B cell P53 expression through ROS-Akt-DNMT3B pathway-mediated promoter hypermethylation. 2016 Apr 12 2
67 27010918 Heat Killed Attenuated Leishmania Induces Apoptosis of HepG2 Cells Through ROS Mediated p53 Dependent Mitochondrial Pathway. 2016 3
68 27124102 Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways. 2016 Jun 2 2
69 27414741 ROS-mediated apoptosis of HAPI microglia through p53 signaling following PFOS exposure. 2016 Sep 3
70 27422544 p53 and mitochondrial dysfunction: novel insight of neurodegenerative diseases. 2016 Aug 1
71 27542250 Drp1-mediated mitochondrial fission promotes cell proliferation through crosstalk of p53 and NF-κB pathways in hepatocellular carcinoma. 2016 Oct 4 1
72 27568863 Subcellular mechanisms involved in apoptosis induced by aminoglycoside antibiotics: Insights on p53, proteasome and endoplasmic reticulum. 2016 Oct 15 1
73 27703600 Cholesterol Retards Senescence in Bone Marrow Mesenchymal Stem Cells by Modulating Autophagy and ROS/p53/p21Cip1/Waf1 Pathway. 2016 1
74 27711766 Cyclometallated iridium complexes inducing paraptotic cell death like natural products: synthesis, structure and mechanistic aspects. 2016 Sep 27 1
75 32263394 Cancer-targeted tri-block copolymer nanoparticles as payloads of metal complexes to achieve enhanced cancer theranosis. 2016 Jul 14 1
76 32263487 Tailored mesoporous silica nanosystem with enhanced permeability of the blood-brain barrier to antagonize glioblastoma. 2016 Sep 28 1
77 24986024 ROS and p53 in regulation of UVB-induced HDM2 alternative splicing. 2015 Jan-Feb 3
78 25359126 The Apoptotic Effect of Plant Based Nanosilver in Colon Cancer Cells is a p53 Dependent Process Involving ROS and JNK Cascade. 2015 Apr 2
79 25511708 Sigma 1 Receptor antagonist potentiates the anti-cancer effect of p53 by regulating ER stress, ROS production, Bax levels, and caspase-3 activation. 2015 Jan 9 1
80 25537301 Natural borneol enhances bisdemethoxycurcumin-induced cell cycle arrest in the G2/M phase through up-regulation of intracellular ROS in HepG2 cells. 2015 Mar 1
81 26073944 Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock. 2015 Jun 18 1
82 26107995 Functionalized Multiwalled Carbon Nanotubes as Carriers of Ruthenium Complexes to Antagonize Cancer Multidrug Resistance and Radioresistance. 2015 Jul 15 1
83 26180584 Protocatechuic Acid Prevents oxLDL-Induced Apoptosis by Activating JNK/Nrf2 Survival Signals in Macrophages. 2015 1
84 26202022 p53 family members - important messengers in cell death signaling in photodynamic therapy of cancer? 2015 Aug 1
85 26205253 Rational Design of Cancer-Targeted Benzoselenadiazole by RGD Peptide Functionalization for Cancer Theranostics. 2015 Sep 1
86 26368019 Gypenosides Synergistically Enhances the Anti-Tumor Effect of 5-Fluorouracil on Colorectal Cancer In Vitro and In Vivo: A Role for Oxidative Stress-Mediated DNA Damage and p53 Activation. 2015 2
87 26465677 A Novel Platinum-Maurocalcine Conjugate Induces Apoptosis of Human Glioblastoma Cells by Acting through the ROS-ERK/AKT-p53 Pathway. 2015 Dec 7 1
88 24269727 ROS and RNS induced apoptosis through p53 and iNOS mediated pathway by a dibasic hydroxamic acid molecule in leukemia cells. 2014 Feb 14 2
89 24366007 Nutlin-3 induces HO-1 expression by activating JNK in a transcription-independent manner of p53. 2014 Mar 3
90 24412988 p53 and mitochondrial function in neurons. 2014 Aug 1
91 24491546 Phenethyl isothiocyanate sensitizes glioma cells to TRAIL-induced apoptosis. 2014 Apr 18 1
92 24555485 Synergistic induction of apoptosis by methylseleninic acid and cisplatin, the role of ROS-ERK/AKT-p53 pathway. 2014 Apr 7 1
93 24787294 Tumor microenvironment in head and neck squamous cell carcinoma. 2014 Apr 1
94 24867259 Nutlin-3 induces BCL2A1 expression by activating ELK1 through the mitochondrial p53-ROS-ERK1/2 pathway. 2014 Aug 2
95 25087850 Mixed-ligand ruthenium polypyridyl complexes as apoptosis inducers in cancer cells, the cellular translocation and the important role of ROS-mediated signaling. 2014 Dec 7 1
96 25135223 Strategy to enhance the anticancer efficacy of X-ray radiotherapy in melanoma cells by platinum complexes, the role of ROS-mediated signaling pathways. 2014 Nov 1 1
97 25305377 Abrus precatorius agglutinin-derived peptides induce ROS-dependent mitochondrial apoptosis through JNK and Akt/P38/P53 pathways in HeLa cells. 2014 Oct 5 1
98 25350363 ROS-mediated cytotoxic effect of copper(II) hydrazone complexes against human glioma cells. 2014 Oct 27 1
99 26432589 Differential effects of p53 on bystander phenotypes induced by gamma ray and high LET heavy ion radiation. 2014 Apr 2
100 32261761 pH-responsive cancer-targeted selenium nanoparticles: a transformable drug carrier with enhanced theranostic effects. 2014 Sep 7 1