Palmitates

insulin ; Homo sapiens







252 Article(s)
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201 17219404 Fatty acid-induced defects in insulin signalling, in myotubes derived from children, are related to ceramide production from palmitate rather than the accumulation of intramyocellular lipid. 2007 Apr 2
202 17337731 Key role for ceramides in mediating insulin resistance in human muscle cells. 2007 Apr 27 2
203 17431009 Insulin protects liver cells from saturated fatty acid-induced apoptosis via inhibition of c-Jun NH2 terminal kinase activity. 2007 Jul 3
204 17434141 Fatty acid represses insulin receptor gene expression by impairing HMGA1 through protein kinase Cepsilon. 2007 Jun 1 2
205 17435330 Molecular mechanism of insulin resistance. 2007 Mar 3
206 17478729 Toll-like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity. 2007 Jun 8 2
207 17482433 Insulin resistance and the mitochondrial link. Lessons from cultured human myotubes. 2007 Jul 1
208 17550999 Two phases of palmitate-induced insulin resistance in skeletal muscle: impaired GLUT4 translocation is followed by a reduced GLUT4 intrinsic activity. 2007 Sep 8
209 17698034 Activation of mammalian target of rapamycin complex 1 and insulin resistance induced by palmitate in hepatocytes. 2007 Oct 12 2
210 18198644 [Molecular mechanism of berberine in improving insulin resistance induced by free fatty acid through inhibiting nuclear trascription factor-kappaB p65 in 3T3-L1 adipocytes]. 2007 Dec 2
211 24557677 Inhibition of protein kinase B by palmitate in the insulin signaling of HepG2 cells and the preventive effect of arachidonic acid on insulin resistance. 2007 May 5
212 16327015 Perfused hearts from Type 2 diabetic (db/db) mice show metabolic responsiveness to insulin. 2006 May 2
213 16442843 Triacylglycerol accumulation is not primarily affected in myotubes established from type 2 diabetic subjects. 2006 Jan 2
214 16487789 New insights into fatty acid modulation of pancreatic beta-cell function. 2006 1
215 16609702 Leptin biosynthetic pathway in white adipocytes. 2006 Apr 1
216 16815692 Long-chain Acyl-CoA is not primarily increased in myotubes established from type 2 diabetic subjects. 2006 Jul 1
217 16849630 Apoptosis in skeletal muscle myotubes is induced by ceramides and is positively related to insulin resistance. 2006 Dec 1
218 17097017 Effects of fatty acid regulation on visfatin gene expression in adipocytes. 2006 Oct 20 2
219 15627256 Cyclodextrin-polyethylenimine conjugates for targeted in vitro gene delivery. 2005 Feb 20 1
220 15654918 Lipid metabolism in human skeletal muscle cells: effects of palmitate and chronic hyperglycaemia. 2005 Jan 1
221 15894466 Reduced insulin-mediated citrate synthase activity in cultured skeletal muscle cells from patients with type 2 diabetes: evidence for an intrinsic oxidative enzyme defect. 2005 Jun 30 1
222 15972273 On the suppression of plasma nonesterified fatty acids by insulin during enhanced intravascular lipolysis in humans. 2005 Nov 1
223 16203862 PGC-1alpha gene expression is down-regulated by Akt- mediated phosphorylation and nuclear exclusion of FoxO1 in insulin-stimulated skeletal muscle. 2005 Dec 3
224 14988236 Reduced lipid oxidation in skeletal muscle from type 2 diabetic subjects may be of genetic origin: evidence from cultured myotubes. 2004 Mar 1
225 15105415 Increased beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation. 2004 Jun 25 1
226 15252018 Fatty acid-induced insulin resistance in L6 myotubes is prevented by inhibition of activation and nuclear localization of nuclear factor kappa B. 2004 Oct 1 2
227 15448091 Evidence against the involvement of oxidative stress in fatty acid inhibition of insulin secretion. 2004 Oct 1
228 15536603 Insulin regulation of free fatty acid kinetics in adult cystic fibrosis patients with impaired glucose tolerance. 2004 Nov 1
229 12447984 Pleiotropic effects of fatty acids on pancreatic beta-cells. 2003 Jan 1
230 14605989 Skeletal muscle cells from insulin-resistant (non-diabetic) individuals are susceptible to insulin desensitization by palmitate. 2003 Oct 4
231 11781146 Metabolic consequence of long-term exposure of pancreatic beta cells to free fatty acid with special reference to glucose insensitivity. 2002 Jan 2 1
232 11815454 Triggering of insulin release by a combination of cAMP signal and nutrients: an ATP-sensitive K+ channel-independent phenomenon. 2002 Feb 1
233 11833043 Thiazolidinediones enhance insulin-mediated suppression of fatty acid flux in type 2 diabetes mellitus. 2002 Feb 1
234 12688632 Insulin secretion induced by palmitate--a process fully dependent on glucose concentration. 2002 Dec 1
235 11319727 Effects of free fatty acids on beta-cell functions: a possible involvement of peroxisome proliferator-activated receptors alpha or pancreatic/duodenal homeobox. 2001 May 1
236 11350782 Systemic and regional free fatty acid metabolism in type 2 diabetes. 2001 Jun 1
237 11500316 Insulin increases FA uptake and esterification but reduces lipid utilization in isolated contracting muscle. 2001 Sep 4
238 10830281 Long-chain acyl CoA regulation of protein kinase C and fatty acid potentiation of glucose-stimulated insulin secretion in clonal beta-cells. 2000 Jun 1
239 10950823 Palmitate oxidation rate and action on glycogen synthase in myoblasts from insulin-resistant subjects. 2000 Sep 3
240 9892216 Insulin regulation of regional free fatty acid metabolism. 1999 Jan 1
241 10389846 Enhancing effects of long-term elevated glucose and palmitate on stored and secreted proinsulin-to-insulin ratios in human pancreatic islets. 1999 Jul 6
242 10542046 Cross-talk mechanisms in the development of insulin resistance of skeletal muscle cells palmitate rather than tumour necrosis factor inhibits insulin-dependent protein kinase B (PKB)/Akt stimulation and glucose uptake. 1999 Nov 2
243 9519739 Palmitate and myristate selectively mimic the effect of glucose in augmenting insulin release in the absence of extracellular Ca2+. 1998 Mar 1
244 9593779 Insulin therapy in burn patients does not contribute to hepatic triglyceride production. 1998 May 15 2
245 9267983 Fatty acid induced insulin resistance in rat-1 fibroblasts overexpressing human insulin receptors: impaired insulin-stimulated mitogen-activated protein kinase activity. 1997 Aug 1
246 9322948 Fatty acid-induced insulin resistance in adipocytes. 1997 Oct 2
247 7634752 Comparative effects of recombinant human insulin-like growth factor I and insulin on whole-body and forearm palmitate metabolism in man. 1995 Jun 4
248 7745004 Long term exposure to fatty acids and ketones inhibits B-cell functions in human pancreatic islets of Langerhans. 1995 May 1
249 16353347 Mechanism of free fatty acid effects on hepatocyte insulin receptor binding and processing. 1993 Jan 1
250 2514599 Norepinephrine inhibits islet lipid metabolism, 45Ca2+ uptake, and insulin secretion. 1989 Dec 1