Palmitates

insulin ; Homo sapiens







252 Article(s)
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51 31524229 GLP‑1 improves palmitate‑induced insulin resistance in human skeletal muscle via SIRT1 activity. 2019 Sep 2
52 31623832 The saturated fatty acid palmitate induces insulin resistance through Smad3-mediated down-regulation of FNDC5 in myotubes. 2019 Dec 10 1
53 32082162 Edgeworthia gardneri (Wall.) Meisn. Water Extract Ameliorates Palmitate Induced Insulin Resistance by Regulating IRS1/GSK3β/FoxO1 Signaling Pathway in Human HepG2 Hepatocytes. 2019 1
54 28842216 Egr2 enhances insulin resistance via JAK2/STAT3/SOCS-1 pathway in HepG2 cells treated with palmitate. 2018 May 1 3
55 29258820 P53 modulates hepatic insulin sensitivity through NF-κB and p38/ERK MAPK pathways. 2018 Jan 15 1
56 29277329 Human embryonic stem cell-derived cardiomyocytes as an in vitro model to study cardiac insulin resistance. 2018 May 2
57 29326365 Disruption of Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Integrity Contributes to Muscle Insulin Resistance in Mice and Humans. 2018 Apr 1
58 29410345 Decreased RNF41 expression leads to insulin resistance in skeletal muscle of obese women. 2018 Jun 1
59 29414761 Global Analyses of Selective Insulin Resistance in Hepatocytes Caused by Palmitate Lipotoxicity. 2018 May 3
60 29601913 Fasting serum amino acids concentration is associated with insulin resistance and pro-inflammatory cytokines. 2018 Jun 2
61 29608879 (-)-Epicatechin and its metabolites prevent palmitate-induced NADPH oxidase upregulation, oxidative stress and insulin resistance in HepG2 cells. 2018 May 15 1
62 29735266 Neuraminidase 1 activates insulin receptor and reverses insulin resistance in obese mice. 2018 Jun 2
63 29794037 Sphingolipid changes do not underlie fatty acid-evoked GLUT4 insulin resistance nor inflammation signals in muscle cells. 2018 Jul 2
64 29813102 Palmitate and insulin counteract glucose-induced thioredoxin interacting protein (TXNIP) expression in insulin secreting cells via distinct mechanisms. 2018 2
65 29976399 Resveratrol protects muscle cells against palmitate-induced cellular senescence and insulin resistance through ameliorating autophagic flux. 2018 Jul 2
66 30111834 The IRE1α-XBP1s pathway promotes insulin-stimulated glucose uptake in adipocytes by increasing PPARγ activity. 2018 Aug 15 1
67 30183308 Palmitate-Induced Insulin Hypersecretion and Later Secretory Decline Associated with Changes in Protein Expression Patterns in Human Pancreatic Islets. 2018 Nov 2 2
68 30307162 Mechanisms of beneficial effects of metformin on fatty acid-treated human islets 2018 Oct 1 2
69 30428550 Possible Prevention of Diabetes with a Gluten-Free Diet. 2018 Nov 13 1
70 30592185 Insulin-stimulated Rac1-GTP binding is not impaired by palmitate treatment in L6 myotubes. 2018 Dec 3
71 27566229 GLP-1 analogue recovers impaired insulin secretion from human islets treated with palmitate via down-regulation of SOCS2. 2017 Jan 5 1
72 28011403 Cyanidin-3-O-glucoside ameliorates palmitate-induced insulin resistance by modulating IRS-1 phosphorylation and release of endothelial derived vasoactive factors. 2017 Mar 1
73 28111233 CtBP2 ameliorates palmitate-induced insulin resistance in HepG2 cells through ROS mediated JNK pathway. 2017 Jun 1 2
74 28161417 Celastrol attenuates mitochondrial dysfunction and inflammation in palmitate-mediated insulin resistance in C3A hepatocytes. 2017 Mar 15 5
75 28302654 Palmitate-Induced Vacuolar-Type H+-ATPase Inhibition Feeds Forward Into Insulin Resistance and Contractile Dysfunction. 2017 Jun 2
76 28323973 How to Measure Adipose Tissue Insulin Sensitivity. 2017 Apr 1 2
77 28377722 Curcumin Improves Palmitate-Induced Insulin Resistance in Human Umbilical Vein Endothelial Cells by Maintaining Proteostasis in Endoplasmic Reticulum. 2017 3
78 28380411 Paeoniflorin suppresses lipid accumulation and alleviates insulin resistance by regulating the Rho kinase/IRS-1 pathway in palmitate-induced HepG2Cells. 2017 Jun 3
79 28483801 Intramyocellular Ceramides: Subcellular Concentrations and Fractional De Novo Synthesis in Postabsorptive Humans. 2017 Aug 2
80 28584168 Palmitate and oleate exert differential effects on insulin signalling and glucose uptake in human skeletal muscle cells. 2017 Jul 1
81 28680093 Basal hypersecretion of glucagon and insulin from palmitate-exposed human islets depends on FFAR1 but not decreased somatostatin secretion. 2017 Jul 5 5
82 28731188 Hispidin rescues palmitate‑induced insulin resistance in C2C12 myotubes. 2017 Oct 3
83 28742858 Reduction of endoplasmic reticulum- mitochondria interactions in beta cells from patients with type 2 diabetes. 2017 1
84 28802581 PKM2 aggravates palmitate-induced insulin resistance in HepG2 cells via STAT3 pathway. 2017 Oct 7 1
85 28835436 In vitro contraction protects against palmitate-induced insulin resistance in C2C12 myotubes. 2017 Nov 1 3
86 28914811 Leptolide Improves Insulin Resistance in Diet-Induced Obese Mice. 2017 Sep 15 2
87 28980863 Addition of exogenous sodium palmitate increases the IAPP/insulin mRNA ratio via GPR40 in human EndoC-βH1 cells. 2017 Aug 2
88 29093351 Effects of Ursodeoxycholic Acid and Insulin on Palmitate-Induced ROS Production and Down-Regulation of PI3K/Akt Signaling Activity. 2017 4
89 29362600 Palmitate-induced insulin resistance is attenuated by Pioglitazone and EGCG through reducing the gluconeogenic key enzymes expression in HepG2 cells. 2017 Oct-Dec 2
90 26337904 IRE1α and TRB3 do not contribute to the disruption of proximal insulin signaling caused by palmitate in C2C12 myotubes. 2016 Jan 1
91 26698173 Sustained Action of Ceramide on the Insulin Signaling Pathway in Muscle Cells: IMPLICATION OF THE DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASE. 2016 Feb 5 1
92 26983645 Anti-diabetic effect of 3-hydroxy-2-naphthoic acid, an endoplasmic reticulum stress-reducing chemical chaperone. 2016 May 15 4
93 27064244 Initial hyperinsulinemia and subsequent β-cell dysfunction is associated with elevated palmitate levels. 2016 Aug 4
94 27104558 Insulin Protects Hepatic Lipotoxicity by Regulating ER Stress through the PI3K/Akt/p53 Involved Pathway Independently of Autophagy Inhibition. 2016 Apr 19 1
95 27313850 Addition of a dairy fraction rich in milk fat globule membrane to a high-saturated fat meal reduces the postprandial insulinaemic and inflammatory response in overweight and obese adults. 2016 1
96 27423393 PINK1 alleviates palmitate induced insulin resistance in HepG2 cells by suppressing ROS mediated MAPK pathways. 2016 Sep 9 1
97 25342132 Acylcarnitines: potential implications for skeletal muscle insulin resistance. 2015 Jan 1
98 25445050 Free fatty acid induced impairment of insulin signaling is prevented by the diastereomeric mixture of calophyllic acid and isocalophyllic acid in skeletal muscle cells. 2015 Jan 5 2
99 25527164 Palmitate induces insulin resistance in human HepG2 hepatocytes by enhancing ubiquitination and proteasomal degradation of key insulin signaling molecules. 2015 Jan 15 14
100 25600807 TRAM1 protect HepG2 cells from palmitate induced insulin resistance through ER stress-JNK pathway. 2015 Feb 20 2