Zinc

insulin ; Homo sapiens







116 Article(s)
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51 22277170 Poor zinc status is associated with increased risk of insulin resistance in Spanish children. 2012 Feb 4
52 23023423 [Development research of new Zn complexes with anti-diabetic effect--structure-activity-related studies by displacement of coordination atom]. 2012 1
53 20927436 Novel use of fluorescent glucose analogues to identify a new class of triazine-based insulin mimetics possessing useful secondary effects. 2011 Feb 1
54 21171943 Metal induced conformational changes in human insulin: crystal structures of Sr2+, Ni2+ and Cu2+ complexes of human insulin. 2011 May 1
55 21626587 Controlled self-assembly of re-engineered insulin by Fe(II). 2011 Jun 20 1
56 20202736 Self-association of Zn-insulin at neutral pH: investigation by concentration gradient--static and dynamic light scattering. 2010 May 2
57 20632994 Zn(II) ions co-secreted with insulin suppress inherent amyloidogenic properties of monomeric insulin. 2010 Sep 15 10
58 21069160 Complexes of hydroxy(thio)pyrone and hydroxy(thio)pyridinone with Zn(II) and Mo(VI). Thermodynamic stability and insulin-mimetic activity. 2010 Mar 1
59 19127548 The proteolytic activity of insulin-degrading enzyme: a mass spectrometry study. 2009 May 1
60 19463741 Ability of GHTD-amide and analogs to enhance insulin activity through zinc chelation and dispersal of insulin oligomers. 2009 Jun 1
61 19770501 A neutron crystallographic analysis of T6 porcine insulin at 2.1 A resolution. 2009 Oct 1
62 20039004 A Molecular Level Understanding of Zinc Activation of C-peptide and its Effects on Cellular Communication in the Bloodstream. 2009 Fall 1
63 18725203 An abnormal pK(a) value of internal histidine of the insulin molecule revealed by neutron crystallographic analysis. 2008 Nov 7 3
64 17497728 Selective oxidation of Zn2+ -insulin catalyzed by Cu2+. 2007 Jul 3
65 19071568 Simultaneous determination of traces of heavy metals by solid-phase spectrophotometry. 2007 Mar 30 1
66 16446456 A fast response mechanism for insulin storage in crystals may involve kink generation by association of 2D clusters. 2006 Feb 7 3
67 16750816 Zinc influx and physiological consequences in the beta-insulinoma cell line, Min6. 2006 Jul 21 1
68 17205988 Selected zinc metabolism parameters in relation to insulin, renin-angiotensin-aldosterone system, and blood pressure in healthy subjects: gender differences. 2006 Winter 1
69 15635658 Insulins with built-in glucose sensors for glucose responsive insulin release. 2005 Jun 1
70 16029032 Albumin-insulin conjugate releasing insulin slowly under physiological conditions: a new concept for long-acting insulin. 2005 Jul-Aug 1
71 16158220 Zinc-ligand interactions modulate assembly and stability of the insulin hexamer -- a review. 2005 Aug 4
72 16158222 ZnT-8, a pancreatic beta-cell-specific zinc transporter. 2005 Aug 1
73 15129976 Optimum formulation for sustained-release insulin. 2004 Mar 1 2
74 15516700 Effect of chromium and zinc on insulin signaling in skeletal muscle cells. 2004 Oct 4
75 15597541 Simultaneous monitoring of Zn2+ secretion and intracellular Ca2+ from islets and islet cells by fluorescence microscopy. 2004 Dec 1
76 12906931 Antidiabetic and antimalarial biguanide drugs are metal-interactive antiproteolytic agents. 2003 Aug 15 1
77 14684753 Insulin clearance in obesity. 2003 Dec 1
78 11817952 Detection and imaging of zinc secretion from pancreatic beta-cells using a new fluorescent zinc indicator. 2002 Feb 6 1
79 11396782 Plasma status of selected minerals in hypertensive men with and without insulin resistance. 2001 Apr 1
80 11404220 Zinc stimulates the activity of the insulin- and nutrient-regulated protein kinase mTOR. 2001 Jul 1
81 10701254 Detection of secretion from single pancreatic beta-cells using extracellular fluorogenic reactions and confocal fluorescence microscopy. 2000 Feb 15 3
82 10725096 Synthesis and characterization of poly(ethylene glycol)-insulin conjugates. 2000 Mar-Apr 3
83 10920035 Characterization of the oligomeric states of insulin in self-assembly and amyloid fibril formation by mass spectrometry. 2000 Aug 1
84 11009601 Structural effects of protein lipidation as revealed by LysB29-myristoyl, des(B30) insulin. 2000 Oct 3 1
85 9949729 Characterization of allosteric insulin hexamers by electrospray ionization mass spectrometry. 1999 Jan 15 1
86 9987035 Zn2+ entry produces oxidative neuronal necrosis in cortical cell cultures. 1999 Jan 1
87 9546200 NMR triple-quantum filtered relaxation analysis of 17O-water in insulin solutions: an insight into the aggregation of insulin and the properties of its bound water. 1998 Mar 9 1
88 9550453 Zinc, insulin and diabetes. 1998 Apr 2
89 9153424 Mechanisms of stabilization of the insulin hexamer through allosteric ligand interactions. 1997 May 13 4
90 9245420 Carboxylate ions are strong allosteric ligands for the HisB10 sites of the R-state insulin hexamer. 1997 Aug 12 1
91 7654714 A spectroscopic investigation of the conformational dynamics of insulin in solution. 1995 Aug 22 1
92 8562282 Endocrine interaction between zinc and prolactin. An interpretative review. 1995 Aug-Sep 1
93 8102964 Some non-traditional aspects on the regulation of glucose assimilation in the small intestine. 1993 Aug 1
94 8441924 Immunoelectrophoretic characterization of insulin monomers and polymers. 1993 Mar 6
95 1438163 Altering the association properties of insulin by amino acid replacement. 1992 Sep 1
96 1671209 X-ray structure of an unusual Ca2+ site and the roles of Zn2+ and Ca2+ in the assembly, stability, and storage of the insulin hexamer. 1991 Jan 29 1
97 1827378 [Absorption of short-acting insulin mixed with different slow-release formulations]. 1991 Jan 31 2
98 1894879 Effect of mitogenic and hormonal stimulation on zinc transport in mixed lymphocyte cultures. 1991 Jun 1
99 2012830 The self-association of zinc-free human insulin and insulin analogue B13-glutamine. 1991 Jan 5
100 2488172 Application of scanning electron microscopy and energy-dispersive X-ray analysis to the solution behaviour of Zn-insulin: precipitation phenomena. 1989 6