| 1 |
32383521 | Biotin, coenzyme Q10, and their combination ameliorate aluminium chloride-induced Alzheimer's disease via attenuating neuroinflammation and improving brain insulin signaling. | 2020 May 8 |
1 |
| 2 |
26321373 | Insulin treatment promotes tyrosine phosphorylation of PKR and inhibits polyIC induced PKR threonine phosphorylation. | 2015 Nov 1 |
1 |
| 3 |
22974292 | 3D-QSAR studies on a series of 2,4-thiazolidinedione derivatives: a self- organizing molecular field analysis approach to design novel PTP 1B inhibitors. | 2013 Sep |
1 |
| 4 |
23274913 | Overexpression of TFAM protects 3T3-L1 adipocytes from NYGGF4 (PID1) overexpression-induced insulin resistance and mitochondrial dysfunction. | 2013 Jul |
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| 5 |
23325788 | Regulatory mode shift of Tbc1d1 is required for acquisition of insulin-responsive GLUT4-trafficking activity. | 2013 Mar |
1 |
| 6 |
23927930 | Pid1 induces insulin resistance in both human and mouse skeletal muscle during obesity. | 2013 Sep |
1 |
| 7 |
21454690 | AS160 phosphotyrosine-binding domain constructs inhibit insulin-stimulated GLUT4 vesicle fusion with the plasma membrane. | 2011 May 13 |
1 |
| 8 |
20101100 | Protein tyrosine phosphatase 1B gene polymorphisms and essential hypertension: a case-control study in Chinese population. | 2010 Jul-Aug |
1 |
| 9 |
19001411 | The phosphotyrosine interactome of the insulin receptor family and its substrates IRS-1 and IRS-2. | 2009 Mar |
1 |
| 10 |
19297450 | Inhibition of insulin-stimulated hydrogen peroxide production prevents stimulation of sodium transport in A6 cell monolayers. | 2009 Jun |
1 |
| 11 |
19427337 | Caveolin-2 regulation of STAT3 transcriptional activation in response to insulin. | 2009 Jul |
1 |
| 12 |
17940160 | Insulin resistance induced by tumor necrosis factor-alpha in myocytes and brown adipocytes. | 2008 Apr |
2 |
| 13 |
18268350 | Dissection of the insulin signaling pathway via quantitative phosphoproteomics. | 2008 Feb 19 |
1 |
| 14 |
18629684 | Insulin resistance associated to obesity: the link TNF-alpha. | 2008 Jul |
2 |
| 15 |
17370312 | PD98059 enhanced insulin, cytokine, and growth factor activation of xanthine oxidoreductase in epithelial cells involves STAT3 and the glucocorticoid receptor. | 2007 Aug 15 |
1 |
| 16 |
16602692 | Proteomic analysis reveals novel molecules involved in insulin signaling pathway. | 2006 Apr |
1 |
| 17 |
17019595 | Exercise training increases insulin-stimulated glucose disposal and GLUT4 (SLC2A4) protein content in patients with type 2 diabetes. | 2006 Dec |
1 |
| 18 |
15664450 | Distinct Grb10 domain requirements for effects on glucose uptake and insulin signaling. | 2005 Jan 31 |
2 |
| 19 |
15919813 | Association testing of the protein tyrosine phosphatase 1B gene (PTPN1) with type 2 diabetes in 7,883 people. | 2005 Jun |
2 |
| 20 |
15504985 | Association of protein tyrosine phosphatase 1B gene polymorphisms with measures of glucose homeostasis in Hispanic Americans: the insulin resistance atherosclerosis study (IRAS) family study. | 2004 Nov |
1 |
| 21 |
12663464 | Defective signaling through Akt-2 and -3 but not Akt-1 in insulin-resistant human skeletal muscle: potential role in insulin resistance. | 2003 Apr |
1 |
| 22 |
11606564 | Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action. | 2002 Jan 11 |
1 |
| 23 |
11818508 | The effects of intracellular calcium depletion on insulin signaling in 3T3-L1 adipocytes. | 2002 Feb |
3 |
| 24 |
12384996 | Insulin stimulates spreading of skeletal muscle cells involving the activation of focal adhesion kinase, phosphatidylinositol 3-kinase and extracellular signal regulated kinases. | 2002 Nov |
1 |
| 25 |
11246877 | Insulin resistance with enhanced insulin signaling in high-salt diet-fed rats. | 2001 Mar |
1 |
| 26 |
11408264 | Insulin and IGF-I inhibit calcium-dependent chloride secretion by T84 human colonic epithelial cells. | 2001 Jul |
1 |
| 27 |
11526109 | Insulin receptor substrate-1 pleckstrin homology and phosphotyrosine-binding domains are both involved in plasma membrane targeting. | 2001 Nov 2 |
1 |
| 28 |
11723060 | Insulin signal transduction in skeletal muscle from glucose-intolerant relatives of type 2 diabetic patients [corrected]. | 2001 Dec |
2 |
| 29 |
10768093 | Natural variants of human p85 alpha phosphoinositide 3-kinase in severe insulin resistance: a novel variant with impaired insulin-stimulated lipid kinase activity. | 2000 Mar |
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| 30 |
10868945 | Characterization of signal transduction and glucose transport in skeletal muscle from type 2 diabetic patients. | 2000 Feb |
2 |
| 31 |
10037694 | Phosphotyrosine binding domains of Shc and insulin receptor substrate 1 recognize the NPXpY motif in a thermodynamically distinct manner. | 1999 Mar 5 |
1 |
| 32 |
10066387 | Insulin-inducible changes in the relative ratio of PTP1B splice variants. | 1999 Mar |
1 |
| 33 |
10356365 | The SH3 and BH domains of the p85alpha adapter subunit play a critical role in regulating class Ia phosphoinositide 3-kinase function. | 1999 May |
1 |
| 34 |
10497255 | Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function. | 1999 Oct 1 |
1 |
| 35 |
10525667 | Search for variants of the gene-promoter and the potential phosphotyrosine encoding sequence of the insulin receptor substrate-2 gene: evaluation of their relation with alterations in insulin secretion and insulin sensitivity. | 1999 Oct |
1 |
| 36 |
9421434 | Ligand-independent GLUT4 translocation induced by guanosine 5'-O-(3-thiotriphosphate) involves tyrosine phosphorylation. | 1998 Jan |
1 |
| 37 |
9514773 | Development of an assay for bioactive insulin. | 1998 Mar 15 |
1 |
| 38 |
9582374 | Guanosine 5'-O-(3-thiotriphosphate) (GTPgammaS) stimulation of GLUT4 translocation is tyrosine kinase-dependent. | 1998 May 22 |
1 |
| 39 |
9651339 | Evidence that IRS-2 phosphorylation is required for insulin action in hepatocytes. | 1998 Jul 10 |
1 |
| 40 |
9833943 | Regional difference in insulin inhibition of non-esterified fatty acid release from human adipocytes: relation to insulin receptor phosphorylation and intracellular signalling through the insulin receptor substrate-1 pathway. | 1998 Nov |
1 |
| 41 |
8999839 | Protein-tyrosine phosphatase 1B complexes with the insulin receptor in vivo and is tyrosine-phosphorylated in the presence of insulin. | 1997 Jan 17 |
1 |
| 42 |
9261155 | A novel 160-kDa phosphotyrosine protein in insulin-treated embryonic kidney cells is a new member of the insulin receptor substrate family. | 1997 Aug 22 |
1 |
| 43 |
9280070 | Phosphoinositide 3-kinase is required for insulin-induced but not for growth hormone- or hyperosmolarity-induced glucose uptake in 3T3-L1 adipocytes. | 1997 Sep |
1 |
| 44 |
9341192 | Osmotic shock stimulates GLUT4 translocation in 3T3L1 adipocytes by a novel tyrosine kinase pathway. | 1997 Oct 24 |
1 |
| 45 |
8557631 | The beta-adrenergic receptor is a substrate for the insulin receptor tyrosine kinase. | 1996 Jan 12 |
1 |
| 46 |
8615821 | Activation of phosphatidylinositol 3-kinase by concanavalin A through dual signaling pathways, G-protein-coupled and phosphotyrosine-related, and an essential role of the G-protein-coupled signals for the lectin-induced respiratory burst in human monocytic THP-1 cells. | 1996 Apr 15 |
2 |
| 47 |
8713074 | Synergistic activation of PtdIns 3-kinase by tyrosine-phosphorylated peptide and beta gamma-subunits of GTP-binding proteins. | 1996 Jul 15 |
2 |
| 48 |
8824262 | Functional roles of the Shc phosphotyrosine binding and Src homology 2 domains in insulin and epidermal growth factor signaling. | 1996 Oct 18 |
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| 49 |
7531337 | Protein-tyrosine-phosphatase SHPTP2 is a required positive effector for insulin downstream signaling. | 1995 Jan 31 |
1 |
| 50 |
7537758 | Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects. | 1995 May |
3 |